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Genotype-Rx
Genotype-Pheno
Genotype-Clinical
hiv
db
program
»
Analyze sequence sets for proportions with Surveillance Drug Resistance Mutations (SDRMs)
»
Interactive map
displaying HIV-1 drug resistance in ARV-naive populations
»
XML Suite of Treatment-Change Episodes
ART-AiDE
AR
V
T
herapy -
A
cqu
i
sition &
D
isplay
E
ngine
Database Mirror
Collaboration with Africa Centre for Health and Population Studies and South African MRC
HBVseq Program
Provides
HBV RT
mutation frequencies by genotype and treatment.
»
HBVseq
; »
ReleaseNotes
Interactive map displaying HIV-1 drug resistance in ARV-naive population
Studies of ARV-naive population by region, year and subtype. »
Interactive map
GENOTYPE-TREATMENT CORRELATIONS
Retrieve sequences (and/or mutations) from persons receiving selected HIV drugs
Retrieve sequences and treatments from viruses with specific mutations
ESSENTIAL DATA ON DRMS
Prevalence of DRMs in ARV-naive and -treated patients and their contributions to reduced drug susceptibility:
NRTI
,
NNRTI
,
PI
&
INI
GENOTYPE-PHENOTYPE CORRELATIONS
Retrieve drug susceptibility data for isolates with selected mutations
Download genotype-phenotype research datasets
SURVEILLANCE MUTATIONS
World Health Organization 2009 Mutation List
Geographic Information System
Surveillance Drug Resistance Mutation (SDRM) Worksheet
GENOTYPE-CLINICAL CORRELATIONS
Summaries of genotype-clinical outcome studies
Genotype-clinical outcome datasets (download)
REFERENCES
Published drug resistance studies in HIVDB
Published studies by Stanford database group
ADDITIONAL RESOURCES
Panels of multi-drug resistant recombinant infectious molecular clones, donated to the NIH AIDS Reagent Program:
NRTI, NNRTI, PI & RAL
REGA HIV-1 Subtyping Tool
Version 3.0
HIV-1 drug reistance mutations for
Point-Of-Care (POC) genotypic resistance tests
HIV-1 genetic variability program for
POC genotypic drug resistance hybridization assays
NEW SUBMISSIONS
Steegen et al.
Sequences from Ugandan children initiating 1-st line ART.
Hachiya et al.
Integrase sequences from ARV-naïve individuals in Germany, 1986 - 2006.
Chaplin et al.
Interprets user-entered mutations to infer the level of resistance to NRTIs, NNRTIs, PIs and INSTIs.
Drug Resistance Summaries (
pdf
)
PIs
NRTIs
NNRTIs
INSTIs
MARVEL
»
M
utation
ARV
E
vidence
L
isting
HIVseq Program
»
Provides mutation frequencies by subtype and treatment
HIValg Program
»
Compare HIVdb, ANRS, Rega, or create your own algorithm