Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

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HIV Treatment Websites

 
  1. Clinical Guidelines and Drug Information
  2. Antiretroviral Drug Prescribing Information
  3. Educational and CME Sites
  4. Biomedical Journals
  5. HIV-Related Scientific Meetings and Conferences
  6. HIV/AIDS Research Databases
  7. Clinical Trials
  8. Telephone Consultation Services
 

Last updated: 10/12/09

Clinical Guidelines and Drug Information
Site/URL Description
DHHS: AIDSinfo Clinical GuidelinesGuidelines from the Department of Health and Human Services, including:
    *Adult/adolescent
    *Pediatric
    *Perinatal
    *Post-exposure prophylaxis
    *Opportunistic infections
    *Testing
AIDSinfo Drug Database Choose an FDA-approved or investigational anti-HIV drug and find links to guideline tables and drug records.
CDC Guidelines Includes CDC guidelines for community planning, counseling and testing, evaluation, occupational and non-occupational post-exposure prophylaxis, patient care, prevention, surveillance, and treatment.
CDC recommendations for HIV testing2006 recommendations for testing of adults, adolescents, and pregnant women.
WHO HIV/AIDS Guidelines World Health Organization guidelines including post-exposure prophylaxis, prevention of mother-to-child transmission, surveillance and public health recommendations, TB-HIV co-management, and the UNAIDS/WHO AIDS Epidemic Update 2007.
IAPAC Drug Guide 2007 Clear, concise summaries of all FDA-approved drugs, including visuals.
HIV Drug Interactions Check for drug interactions and pharmacology resources. Developed and maintained by the University of Liverpool.
PDR.net Comprehensive drug information including the full text of package inserts. Downloadable drug interactions to PDA available. Registration required (free).
HIV Drug Resistance Program National Cancer Institute-funded program on HIV drug resistance
BHIVA Guidelines British HIV Association guidelines including management of HIV infection in pregnant women, immunization and treatment, HIV associated malignancies, and HBV-HIV, HCV-HIV, and TB-HIV co-infection.
Medical Management of HIV Infection Manual of diagnosis and treatment by Drs. John G. Bartlett and Joel E. Gallant, Johns Hopkins University. Requires log-in (free).
IDSA Practice Guidelines for the Treatment of Tuberculosis Infectious Disease Society of America guidelines, published 2003.

Drug Prescribing Information
Drug Name(s) Trade Name(s) and Package Inserts* Additional names Manufacturer**
Nucleoside Reverse Transcriptase Inhibitors (NRTIs)
abacavir Ziagen® ABC GSK
didanosine Videx® ddI BMS
emtricitabine Emtriva® FTC Gilead
lamivudine Epivir® 3TC GSK
stavudine Zerit® d4T BMS
tenofovir Viread® TDF, PMPA Gilead
zalcitabine HIVID® ddC Roche
zidovudine Retrovir® AZT, ZDV GSK
Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs)
delavirdine Rescriptor® DLV Pfizer
efavirenz Sustiva® EFV BMS
etravirine Intelence® ETV Tibotec
nevirapine Viramune® NVP Boehringer Ingelheim
Protease Inhibitors (PIs)
amprenavir (discontinued) Agenerase® GSK
atazanavir Reyataz® ATV BMS
darunavir Prezista® DRV Tibotec
lopinavir and ritonavir Kaletra® LPV/r Abbott
fosamprenavir Lexiva® FPV GSK
indinavir Crixivan® IDV Merck
nelfinavir Viracept® NFV Pfizer
ritonavir Norvir® RTV Abbott
saquinavir Invirase® SQV Roche
tipranavir Aptivus® TPV Boehringer Ingelheim
Fusion Inhibitors
enfurvirtide Fuzeon® T-20, ENF Roche
Entry Inhibitors
maraviroc Selzentry® MVC Pfizer
Integrase Inhibitors (INIs)
raltegravir Isentress® RAL Merck
Fixed Dose Combinations
abacavir and lamivudine Epzicom® ABC/3TC GSK
zidovudine and lamivudine Combivir® AZT/3TC GSK
abacavir, lamivudine, and zidovudine Trizivir® ABC/3TC/AZT GSK
tenofovir and emtricitabine Truvada® TDF/FTC Gilead
tenofovir, emtricitabine, and efavirenz Atripla® TDF/FTC/EFV Gilead, BMS
Generic Fixed Dose Combinations
lamivudine and zidovudine Duovir 3TC/ZDV Cipla
nevirapine, lamivudine, and zidovudine Duovir-N NVP/3TC/ZDV Cipla
nevirapine, lamivudine, and stavudine Triomune NVP/3TC/d4T Cipla
* See Drugs@FDA to search approval/label history and related documents by brand name.
** GSK = GlaxoSmithKline; BMS = Bristol-Myers Squibb.

Educational and CME Sites
Site/URL Description
Clinical Care Options for HIV HIV treatment updates, conference coverage, slide sets, and tools. Registration required (free).
National AIDS Treatment Advocacy Project (NATAP) Comprehensive coverage of publications and news on HIV treatment.
HIVandHepatitis.com Up to date news coverage and conference highlights.
Medscape HIV/AIDS Extensive resource centers, journals, and news on a number of conditions. Registration required (free).
IAS-USAInternational AIDS Society-USA resources, including CME course offerings, online case-based CME modules, full-text electronic versions of Topics in HIV Medicine issues, and other resources
Johns Hopkins AIDS Service POC-IT HIV Guide. Registration required (free).
AIDS Education Global Information System (AEGIS) Patient newsletters, physician-oriented review journals
The Body News, conference coverage, patient education, "Ask the Experts"
Physicians Research Network Registration required (free).
International Association of Physicians in AIDS Care (IAPAC) Comprehensive listing for both IAPAC members and non-IAPAC conferences.
Aidsmap Community-based organization in the UK.
Project Inform Patient education, Hotline, Outreach programs

Biomedical Journals Publishing Clinical and Scientific HIV Studies
Journal/URL Archives Access Policy
AIDS Full text since 1988 Open access 1 year after publication, to articles back to 1997. Other access requires subscription.
AIDS Research and Human Retroviruses Full text since 1999 Full text requires a subscription or single-paper purchase.
AIDS Reviews Full text since 1999 Open access to all but the two most recent issues, which require a subscription.
Annals of Internal Medicine Full text since 1993 Free access to full text 6 months after publication, as well as to select new articles. Access to most newly published articles requires a subscription.
Antimicrobial Agents and Chemotherapy Full text since 1998, pdf since 1972 Free access to full text 4 months after publication. Access to newly published articles requires a subscription.
Antiviral Therapy Full text since 1999 Subscription needed for full access.
British Medical Journal (BMJ) Full text since 1994 Articles since 1994 can be accessed for free 1 year after publication from the website; back-issues to 1963 are available from PubMed Central. Access to newly published articles requires a subscription.
Clinical Infectious Diseases Full text since 1997 Full issues cannot be downloaded; subscription necessary to view full text or to order back-issues.
HIV Clinical Trials Full text since 2000 Subscription needed for full access.
HIV Medicine Full text since 1999 Full text requires a subscription.
Journal of Acquired Immune Deficiency Syndromes (JAIDS) Full text since 1996 Free access to full text 1 year after publication. Access to newly published articles requires a subscription.
Journal of Clinical Microbiology Full text since 1998, pdf since 1975 Free access to full text 4 months after publication. Access to newly published articles requires a subscription.
Journal of Infectious Dieases Selected full text since 1997 Full issues cannot be downloaded; subscription necessary to view full text or to order back-issues.
Journal of the American Medical Association (JAMA) Full text since 1998, selected pdfs since 1992 Most full text requires one-time access purchase or a subscription.
Journal of Virology Full text since 1998, pdf since 1967 Free access to full text 4 months after publication. Access to newly published articles requires a subscription.
Lancet Full text since 1996 Access to all abstracts and selected full text with free registration. Subscription needed for full access.
MMWR Reports on HIV/AIDS Full text since 1981 Open access.
Nature Full text since 1869 A personal subscription will give you access to the archive dating back to January 1997. Access via a site license includes a minimum of four years; institutions can add additional archived content to their license at any time. Articles can also be published individually.
Nature Medicine Full text since 1995 Some content is freely available without restrictions; some is free but requires registration. Full access requires a subscription.
New England Journal of Medicine (NEJM) Full text since 1993 Subscription needed to view full text.
Proceedings of the National Academy of Sciences (PNAS) Full text since 1915 Open access.
Public Library of Science (PLOS)
*PLOS Biology
*PLOS Medicine
*PLOS Pathogens
Full text since 2003
Full text since 2004
Full text since 2005		 Open access.
Retrovirology Full text since 2004 Open access.
Science Full text since 1997, pdf since 1880 Full text since 1997, 1 year after publication with free registration.
Topics in HIV Medicine Full text since 2000 Open access.

HIV-Related Scientific Meetings and Conferences
Meeting/URL Description
Conference on Retroviruses and Opportunistic
Infections (CROI)		 Sponsored by the Foundation of Retroviral and Human Health, NIAID and CDC. Abstracts (1997 - 2008), Posters (1999 - 2008), and selected presentations (1999 - 2008) are online.
IAS Conferences International AIDS Conferences in Mexico City, 2008 and Cape Town, 2009 sponsored by the International AIDS Society (IAS).
International HIV Drug Resistance Workshop Sponsored by Informed Horizons. See also www.informedhorizons.com for past and future conferences.
Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) American Society for Microbiology. Site contains resources from ICAAC 2002-2009.
Infectious Diseases Society of America (IDSA) Abstracts and videotapes can be ordered online.
International Workshop of HIV Dynamics and Evolution Sponsored by the University of California, San Diego. Submit abstracts and register online.
HIV Drug Resistance Program Symposium:
Antiviral Drug Resistance		 Sponsored by the HIV Drug Resistance Program, National Cancer Institute. Abstracts available online.
European AIDS Conference Sponsored by the European AIDS Clinical Society (EACS). Information on previous conferences can be found here.
European HIV Drug Resistance Workshop Abstracts and presentations from 2008 and 2007 available online.
HIV Pathogenesis Keystone Symposia.
Frontiers in Drug Development for Antiretroviral
Therapies (HIV DART)		 Sponsored by Informed Horizons. See also www.informedhorizons.com for past or future conferences.
Virology Education Large number of medical workshops, conferences, and courses.
South African HIV Drug resistance and bioinformatics workshopsHIV-1 drug resistance and bioinformatics workshops organized in South Africa. It organizes the 4th South African HIV Drug Resistance and Treatment Monitoring Workshop in 2009

HIV/AIDS Research Databases
Database Description
HIV Drug Resistance Database Maintained at Stanford University. Annotated collection of reverse transcriptase and protease sequences linked to drug treatment histories and drug susceptibility test results
Los Alamos National Laboratories Maintained by the Theoretical Biology Group at LANL.
NIAID sites
NCBI Sites
HIV Structural Database Structural database maintained at the NCI devoted to HIV and SIV protease and RT
BioAfrica (Bioinformatics for HIV Research in Africa) Contains information on HIV proteomics, subtype C distribution, and the REGA HIV-1 subtype tool

Clinical Trials
Institution/URL Description
AIDS Treatment Data Network Guide for health-care personnel and patients. Information on AIDS Drug Assistance Programs (ADAP).
AIDSinfo DHHS. Browse and search through clinical trials. Summary of completed and ongoing trials.
ClinicalTrials.gov NIH database of ongoing clinical research trials. Search engine.
The Adult AIDS Clinical Trials Group (ACTG) Password required for ACTG protocols, technical documents (e.g. ACTG Virology Manual), member directory. Public site; www.aactg.org
Centers for AIDS Research (CFAR) Links to each of the CFAR sites.
Bulletin of Experimental Treatments for AIDS (BETA) Bulletin of clinical trials and other resources.

Telephone Consultation Services
Title/URL Description
National Clinicians' Post-Exposure
Prophylaxis Hotline		 24-Hour advice on managing occupational exposures to HIV, hepatitis, and other blood borne pathogens. "PEPline" (888-HIV-4911)
National HIV Telephone Consultation Service Case consultation for physicians, nurses, and other health-care givers. "Warmline" (800-933-3413)
National Perinatal HIV Consultation and
Referral Service		 24-Hour advice on treating infected pregnant women and infants (888-448-8765)

The Team

The Data