Genotype-Phenotype Correlations
![]() Drug susceptibility results (PhenoSense assay) defined as fold-decreased susceptibility
compared to wildtype of viruses containing a mutation at the user-selected position. Results are aggregated
by the pattern of accompanying nonpolymorphic established drug-resistance mutations. Sequences containing
electrophoretic mixtures at a drug-resistance position are excluded from the results. Median, Interquartile
Range, and No. of tests per pattern are shown. The pages with aggregate results contain links to each individual result.
![]() Drug susceptibility results (fold-decreased susceptibility) of viruses
containing one or more user-specfied mutations. Users can retrieve all results on isolates
containing the specified mutations or only those results with exact matches
(at nonpolymorphic established drug-resistance positions) to the specified mutations.
Users can specify the type of assay (PhenoSense, Antivirogram, Other) and whether or
not results on isolates with mixtures will be returned. Queries will return both
graphical and tablular results. Drug susceptibility results defined
as fold-decreased susceptibility.
![]() Drug susceptibility results (PhenoSense assay) of viruses containing
the most common patterns of mutations in the database. Results are aggregated by the pattern
of accompanying nonpolymorphic established drug-resistance mutations. Sequences containing
electrophoretic mixtures at a drug-resistance position are excluded from the results.
Median, Interquartile Range, and No. of tests per pattern are shown.
![]() High quality filtered genotype-phenotype correlation datasets as well as complete unfiltered datasets are provided for download. A R script is also provided for running least squares regression on the high quality filtered datasets.
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