1040 References 72881 Individuals 80670 Time points
148737 Isolates
- 147538 Clinical Isolates, 1199 Lab Isolates
- 148230 HIV-1 Isolates, 279 HIV-2/SIVsm,maq Isolates, 228 NHPL (Non-Human Primate Lentivirus)
158373 Sequences
- 76450 RT Sequences, 75236 Protease Sequences, 6687 Integrase Sequences
- 134884 Sequences from GenBank, 23489 Sequences not in GenBank
2291805 Mutations
- 1435695 RT Mutations, 749261 Protease Mutations, 106849 Integrase Mutations
46071 Phenotype results
- 14402 NRTI, 7966 NNRTI,22818 PI, 885 INI Phenotype results
| Continent | Regions |
|---|
Africa (n = 30405) | South Africa (7634), Uganda (4145), Cameroon (3714), Nigeria (1422), Kenya (1313), Zambia (1272), Zimbabwe (895), Cote d'Ivoire (873), Tanzania (869), Botswana (809), Mali (744), Malawi (603), Ghana (565), Burkina Faso (490), Senegal (476), DRC (464), Angola (430), Mozambique (358), Ethiopia (275), Gabon (263), Benin (257), Algeria (252), Burundi (246), Central African Republic (234), CAR (185), Equatorial Guinea (165), Morocco (165), Togo (162), Rwanda (160), Chad (154), Niger (105), Africa (100), Swaziland (94), Guinea (91), Seychelles (84), Libya (68), Sudan (60), Madagascar (60), Zaire (31), Primate Center (31), Guinea-Bissau (19), Liberia (19), Gambia (18), Congo-Brazzaville (12), Dijibouti (7), Somalia (6), Sierra Leone (3), West Africa (3) | Asia (n = 17465) | China (2664), Taiwan (2616), Vietnam (2251), India (2214), Thailand (2209), Japan (1620), Cambodia (868), Israel (617), Singapore (536), Korea (468), Malaysia (459), Uzbekistan (295), Kazakhstan (189), Iran (104), Republic Of Georgia (91), Saudi Arabia (72), Afghanistan (45), Yemen (44), Myanmar (27), Lebanon (26), Indonesia (24), Turkey (14), Nepal (12) | Europe (n = 28260) | Spain (4540), Italy (3648), France (3401), Germany (2542), Portugal (2237), Sweden (1557), U.K. (1494), Denmark (1115), Russia (1070), Belgium (937), Greece (613), Estonia (556), Switzerland (537), Romania (396), Luxembourg (391), Ukraine (364), Cyprus (311), Netherlands (306), Slovenia (252), Poland (242), Republic of Latvia (234), Austria (201), Norway (194), Bulgaria (160), Greenland (150), Serbia (136), Albania (132), Finland (122), Europe (110), Ireland (88), Azerbaijan (82), Hungary (59), Yugoslavia (33), Slovakia (20), Belarus (18), Moldova (12) | North America (n = 59451) | U.S. (52797), Canada (4412), Cuba (1123), Honduras (672), Mexico (265), Trinidad (66), Puerto Rico (31), Barbados (27), Antigua (16), Saint Vincent (12), Saint Lucia (10), Grenada (8), Dominica (6), North America (3), Montserrat (2), Panama (1) | Oceania (n = 807) | Australia (807) | South America (n = 11687) | Brazil (7412), Argentina (2518), Peru (749), Venezuela (521), Chile (327), Colombia (82), Uruguay (38), Ecuador (12), Guyana (12), Suriname (10), Bolivia (6) |
| NRTI component | NNRTI component | PI component | NRTI + PI or NNRTI regimen |
|---|
AZT (2035) DDI (765) D4T (739) 3TC (263) ABC (222) DDC (219) TDF (32)
AZT/3TC (4271) D4T/3TC (3950) DDI/D4T (1663) AZT/DDI (1557) AZT/DDC (801) DDI/3TC (233) 3TC/TDF (194) D4T/ABC (179) 3TC/ABC (161) DDI/ABC (127) AZT/D4T (85) DDC/D4T (75) DDI/TDF (71) AZT/ABC (60) DDC/3TC (60) FTC/TDF (54) D4T/TDF (30)
AZT/3TC/ABC (535) AZT/DDI/3TC (226) D4T/3TC/ABC (125) DDI/D4T/3TC (102) DDI/D4T/ABC (89) 3TC/ABC/TDF (86) AZT/DDC/3TC (72) AZT/D4T/3TC (57) DDI/3TC/TDF (45) AZT/3TC/TDF (38) D4T/3TC/TDF (31) AZT/DDI/DDC (29) DDI/3TC/ABC (24)
AZT/DDI/D4T/3TC (31) AZT/3TC/ABC/TDF (31)
| NVP (4078) EFV (2853) DLV (191) ETR (10) | NFV (2335) IDV (2212) SQV (934) SQVr (744) LPVr (646) RTV (574) IDVr (369) APV (213) APVr (121) ATV (66) ATVr (55) DRVr (43)
NFV/SQV (212) APV/LPVr (53) IDV/SQV (51) NFV/IDV (45) NFV/RTV (27)
| D4T/3TC/NVP (1337) AZT/3TC/IDV (949) AZT/3TC/EFV (776) D4T/3TC/EFV (699) D4T/3TC/IDV (693) AZT/3TC/NVP (661) AZT/3TC/NFV (620) D4T/3TC/NFV (618) AZT/3TC/SQV (347) DDI/D4T/NFV (341) DDI/D4T/EFV (288) DDI/D4T/NVP (219) D4T/3TC/SQV (199) AZT/3TC/RTV (190) D4T/3TC/SQVr (168) D4T/3TC/RTV (150) DDI/D4T/IDV (139) AZT/3TC/SQVr (122) DDI/D4T/SQVr (120) AZT/DDC/SQV (112) D4T/NFV/NVP (104) AZT/3TC/ABC/EFV (101) AZT/3TC/LPVr (98) AZT/3TC/IDVr (95) D4T/3TC/LPVr (78) D4T/3TC/IDVr (72) DDI/D4T/NFV/EFV (69) D4T/3TC/NFV/NVP (68) AZT/DDI/NVP (68) 3TC/TDF/EFV (59) AZT/DDI/NFV (58) AZT/DDI/IDV (56) AZT/DDI/SQV (53) DDI/D4T/SQV (52) 3TC/TDF/NVP (52) |
| Subtype | protease | RT | integrase |
|---|
| PI-naive | PI-treated | RTI-naive | RTI-treated | INI-naive | INI-treated |
|---|
| B | 16671 | 8202 | 13755 | 19825 | 2224 | 106 | | A | 3109 | 184 | 2516 | 720 | 193 | 1 | | C | 7043 | 446 | 6366 | 3337 | 812 | 1 | | D | 1275 | 125 | 1007 | 444 | 132 | | | F | 831 | 617 | 452 | 483 | 182 | | | G | 1131 | 254 | 958 | 1065 | 104 | | | CRF01_AE | 2845 | 108 | 2453 | 1853 | 369 | | | CRF02_AG | 3302 | 145 | 2400 | 788 | 471 | 2 | | Other | 705 | 109 | 1101 | 544 | 83 | |
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