Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Crystallographic Structures of RT, Protease & Integrase

 
  1. Reverse Transcriptase
  2. Protease
  3. Integrase
 
The Protein Data Bank (PDB), which is maintained by the Research Collaboratory for Structural Bioinformatics, contains approximately 380 protease, 120 reverse transcriptase (RT), and 20 integrase crystallographic structures. These structures have been pivotal to antiretroviral drug design and understanding HIV drug resistance. They have helped clinicians seeking to understand the structural significance of the many HIV-1 drug resistance mutations.