Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Detailed Integrase Inhibitor/Mutation Query

     # of INI       INI Received    
0
1
2
3
4
5
1 - 5
0 - 5
RAL
EVG
DTG
BIC
CAB
Mutation
 CodonAmino Acid
1st
2nd
3rd
4th
5th
6th
7th
 
With No Other Major Mutations
Subtype
Additional Output Options
Complete Rx History
Complete Mutation List
Subtype Data
 
Do not Filter
 
Reset


Enter the number and the specific drugs of interest and/or mutations. If drugs and one or more mutation is selected, then only those mutations occurring in persons receiving the selected drugs will be shown. It is also possible to limit the retrieved sequences to those belonging to a specific species, group, or subtype. Data meeting the criteria will be displayed in a table listing major and minor mutations found in isolates with treatment histories and original literature references. Complete mutation lists, treatment histories and subtype information may be retrieved by selecting the appropriate box under 'Additional Output Options'. The queried dataset will be available for download. Individual and composite alignments will also be available.

To retrieve integrase sequences from persons receiving a selected antiretroviral therapy:

  • Enter # of intergrase inhibitors (INIs) received.
  • Enter specific INIs received.
To retrieve integrase sequences of isolates containing selected mutations:
  • Enter up to seven codons and amino acids of interest.
  • Specify whether the retrieved sequences need to exactly match the entered mutations at major drug resistance mutations. Leaving this box unchecked will retrieve sequences that may include additional major mutations.
To limit the retrieved data to specific species, groups, or subtypes:
  • Enter the species: HIV1 or HIV2
  • Enter the group for HIV1: Main, CPZs or O
  • Enter the subtype for HIV1, Main: All subtypes, B, non-B, or a specific non-B subtype
Optional modifications to the type of data that are returned: Abbreviations:
  • RAL = raltegravir;  EVG = elvitegravir;  DTG = dolutegravir;  BIC = bictegravir; CAB = Cabotegravir

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