Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Integrase inhibitors (INIs) associated Drug Resistance Mutations (DRMs)

PositionMajorDRMMinorDRM
49 G
51 Y
66AIK 
74 MF
75 A
92GVQ 
95 K
97 A
118R 
121CY 
122 N
128 T
138KAT 
140RSAC 
142 T
143CRHKGSA 
145S 
146PRL 
147G 
148HKRN 
149 A
151AL 
153 YFA
155HST 
157 Q
163 RK
230 R
232 N
263K 

The table was updated on 2025-8-4.
All capital letters are one-letter amino acid code; # indicates an insertion; ~ indicates a deletion.