HIV Drug Resistance Database

The HIV Drug Resistance Database Mirror in Southern Africa

Maintained in collaboration between Stanford HIVdb, the Africa Centre for Health and Population Studies (UKZN) and the Biomedical Informatics Research Unit (South African MRC). » Go To Mirror; » More info

HBVseq & HBVrt DB

Like HIVseq, HBVseq accepts HBV RT sequences, determines their genotypes, and compares them to a genotype consensus reference sequence. The differences between the submitted sequence and the consensus reference sequence are used as query parameters for interrogating HBVrt DB to retrieve the prevalence of each mutation according to genotype and treatment. » HBVseq; » HBV Site ReleaseNotes

Retrieve sequences (and/or mutations) from persons receiving selected HIV drugs
Retrieve sequences and treatments from viruses with specific mutations

Summaries of genotype-clinical outcome studies
Genotype-clinical outcome datasets (download)

Retrieve drug susceptibility data for isolates with selected mutations
Download genotype-phenotype research datasets

Published drug resistance studies in HIVRT&PrDB
Published studies by Stanford database group

Ayouba, et al. Drug resistance in recent infections in the ANRS12134 study
Wittkop, et al. Emergence of raltegravir resistance mutations in the Aquitane Cohort
Gatanaga, et al. Transmitted resistance in Japan
Sato, et al. Soltegravir resistance profile
Azijn, et al. Rilpivirine (TMC278) Resistance Profile
Wallis, et al. Drug resistance at ARV failure , South Africa

World Health Organization 2009 Mutation List
Calibrated Population Resistance (CPR) Version 4.1 beta
Mutation Prevalence
Surveillance Drug Resistance Mutation (SDRM) Worksheet

REGA HIV-1 Subtyping Tool Version 2.0

This program interprets user-entered mutations to infer the level of resistance to NRTIs, NNRTIs, PIs. Web Service is available.

HBVseq Program

Provides HBV RT mutation frequencies by genotype and treatment. » Go To Program

ART-AiDE

Antiretroviral Therapy - Acquisition & Display Engine
» Go To Program

MARVEL

MARVEL (Mutation ARV Evidence Listing) » Go To Program

HIVseq Program

Provides mutation frequencies by subtype and treatment. » Go To Program

HIValg Program

Compare HIVdb, ANRS, Rega, or create your own algorithm. » Go To Program

Drug Resistance Summaries

PIs
NRTIs
NNRTIs
FIs
IIs

PDF handouts

» Resistance Mutations

Team

Resources