Kantor R, Smeaton L, Vardhanabhuti S, Hudelson SE, Wallis CL, Tripathy S, Morgado MG, Saravanan S, Balakrishnan P, Reitsma M, Hart S, Mellors JW, Halvas E, Grinsztejn B, Hosseinipour MC, Kumwenda J, La Rosa A, Lalloo UG, Lama JR, Rassool M, Santos BR, Supparatpinyo K, Hakim J, Flanigan T, Kumarasamy N, Campbell TB, Eshleman SH; AIDS Clinical Trials Group (ACTG) A5175 Study Team. Pretreatment HIV Drug Resistance and HIV-1 Subtype C Are Independently Associated With Virologic Failure: Results From the Multinational PEARLS (ACTG A5175) Clinical Trial. Clin Infect Dis. 2015 May 15;60(10):1541-9

PR Data in HIVDB
RT Data in HIVDB

Nucleotide sequences in fasta format
ACTG5175_PR_fasta.txt,   ACTG5175_RT_fasta.txt,   Composite alignment (of sequences at baseline)
ACTG5175_PR_composite.html,   ACTG5175_RT_composite.html,   List of sequences with stop codon, ambiguity codon and unusual residues
ACTG5175_PR_QA.txt,   ACTG5175_RT_QA.txt,   Method: Direct PCR, Dideoxy terminator sequencing
Sample: Plasma
Timing: Multiple timepoints

Integrated view of ARV, genotypes, RNA and CD4 on 415 patients

Downloadable data files

• Treatment history: ACTG5175_RX.html (excel-frendly version ACTG5175_RX.txt)
• Sequences :
  • ACTG5175_PR.html (excel-frendly version ACTG5175_PR.txt)
  • ACTG5175_RT.html (excel-frendly version ACTG5175_RT.txt)
  • ACTG5175_IN.html (excel-frendly version ACTG5175_IN.txt)
• Outcomes:
  • ACTG5175_RNA.html (excel-frendly version ACTG5175_RNA.txt)
    
  • ACTG5175_CD4.html (excel-frendly version ACTG5175_CD4.txt)