The World Health Organization 2009 List of Mutations
for Surveillance of Transmitted Drug Resistant HIV Strains
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NRTI |
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NNRTI |
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PI |
|
M41 | L |
K65 | R |
D67 | N, G, E |
T69 | D, Ins |
K70 | R, E |
L74 | V, I |
V75 | M, T, A, S |
F77 | L |
Y115 | F |
F116 | Y |
Q151 | M |
M184 | V, I |
L210 | W |
T215 | Y, F, I, S, C, D, V, E |
K219 | Q, E, N, R |
|
|
L100 | I |
K101 | E, P |
K103 | N, S |
V106 | M, A |
V179 | F |
Y181 | C, I, V |
Y188 | L, H, C |
G190 | A, S, E |
P225 | H |
M230 | L |
|
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L23 | I |
L24 | I |
D30 | N |
V32 | I |
M46 | I, L |
I47 | V, A
| G48 | V, M |
I50 | V, L |
F53 | L, Y |
I54 | V, L, M, A, T, S |
G73 | S, T, C, A |
L76 | V |
V82 | A, T, F, S, C, M, L |
N83 | D |
I84 | V, A, C |
85 | V |
N88 | D, S |
L90 | M |
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New mutations are in bold
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from Drug Resistance Mutations for Surveillance of Transmitted HIV-1 Drug-Resistance: 2009 Update,
Authors:
Diane E. Bennett1,
Ricardo J. Camacho2,
Dan Otelea3,
Daniel R. Kuritzkes4,
Hervé Fleury5,
Mark Kiuchi6,
Walid Heneine7,
Rami Kantor8,
Michael R. Jordan9,
Jonathan M. Schapiro6,
Anne-Mieke Vandamme10,
Paul Sandstrom11,
Charles A.B. Boucher12,13
David van de Vijver11,
Soo-Yon Rhee6,
Tommy F Liu6,
Deenan Pillay14,
Robert W. Shafer6
1World Health Organization, Geneva, Switzerland;
2Molecular Biology Laboratory, Centro Hospitalar de Lisboa Ocidental, Lisbon, Portugal;
3Molecular Diagnostics, "Prof. Dr. Matei Bals" Institute for Infectious Diseases, Bucharest, Romania;
4Brigham and Women's Hospital Harvard Medical School, Boston MA, USA;
5Laboratoire de Virologie EA 2968, Université de Bordeaux, France;
6Division of Infectious Diseases, Stanford University, Stanford, CA;
7Centers for Disease Control and Prevention, Atlanta, GA, USA;
8Division of Infectious Diseases, Brown University, RI, USA;
9Tufts University School of Medicine, Boston, MA, USA;
10Rega Institute for Medical Research, Katholieke Universiteit Leuven, Belgium,
11Centre for Infectious Disease Prevention and Control, Public Health Agency of Canada, Ottowa, Ontario, Canada;
12Department of Virology, Erasmus MC, University Medical Center Rotterdam, The Netherlands;
13Department of Medical Microbiology. University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands
14Centre for Virology, Division of Infection and Immunity, University College London and Centre for Infections, Health Protection Agency, London UK.
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