<!--#set var="title" value="Database Statistics" --> <!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Database Statistics

As of 2026-02-26

Genotype-Treatment
Number of individuals according to subtype and drug-class experienced1
Subtype 2proteaseRTintegrasecapsid
PI-NaivePI-TreatedRTI-NaiveRTI-TreatedINI-NaiveINI-TreatedCAI-NaiveCAI-Treated
B75,46625,54568,48946,29816,3892,5956,0162
A13,3192,14312,0138,7513,5856813,2900
C30,7436,00721,07628,7717,0227484,9490
D3,9795933,1742,6281,1962791,9390
F2,6871,8862,5091,871750873190
G4,1684141,9573,346440452710
CRF01_AE29,14779526,9867,4463,874343,3780
CRF02_AG10,8024617,5296,4262,1402431,0720
Other20,3922,52621,7578,3711,4892474,44541
Total190,70340,370165,490113,90836,8854,95925,67943
1 Well-characterized treatment history is available for 287,064 individuals from whom 242,992 protease, 257,186 RT, 43,416 integrase and 27,253 capsid isolates have been sequenced and published; "Mutation Prevalence According to Subtype and Treatment" page analyzes sequences obtained from the individuals for each subtype and summarizes the frequency of each mutation from treated individuals in comparison to the frequency of that mutation from untreated individuals.
2 "Other" subtypes include CRFs other than "CRF01_AE" and "CRF02_AG". Appendix II lists the CRFs available in HIVdb and how each CRF was mapped to a subtype for each gene for analysis.

Number of individuals according to regimen received
NRTI componentNNRTI component PI componentNRTI + PI or NNRTI regimen
AZT (2,217)
DDI (817)
D4T (815)
3TC (354)
ABC (264)
DDC (228)
TDF (206)
FTC (14)

AZT/3TC (8,412)
D4T/3TC (7,520)
3TC/TDF (4,838)
FTC/TDF (3,439)
AZT/DDI (1,931)
DDI/D4T (1,831)
3TC/ABC (1,304)
AZT/DDC (835)
DDI/3TC (352)
D4T/ABC (238)
DDI/ABC (186)
DDI/TDF (156)
DDI/FTC (104)
AZT/ABC (104)
AZT/D4T (89)
DDC/D4T (79)
D4T/TDF (70)
ABC/TDF (66)
DDC/3TC (66)
AZT/TDF (59)
3TC/FTC (13)
DDC/ABC (12)
DDI/DDC (12)
D4T/FTC (6)
ABC/FTC (5)
DDC/TDF (5)
AZT/FTC (2)


AZT/3TC/ABC (725)
AZT/3TC/TDF (473)
AZT/DDI/3TC (337)
3TC/ABC/TDF (216)
AZT/D4T/3TC (171)
D4T/3TC/ABC (160)
DDI/D4T/3TC (130)
D4T/3TC/TDF (104)
DDI/3TC/TDF (102)
DDI/D4T/ABC (99)
AZT/DDC/3TC (76)
DDI/FTC/TDF (57)
AZT/FTC/TDF (52)
ABC/FTC/TDF (40)
DDI/3TC/ABC (40)
3TC/FTC/TDF (34)
AZT/DDI/DDC (31)
D4T/FTC/TDF (27)
DDI/D4T/TDF (23)
DDI/ABC/TDF (22)
AZT/DDI/D4T (22)
AZT/DDI/ABC (11)
D4T/ABC/TDF (10)
DDC/D4T/3TC (9)
AZT/DDC/D4T (6)
AZT/ABC/TDF (5)
3TC/ABC/FTC (5)
AZT/DDI/TDF (4)
AZT/DDC/ABC (3)
DDI/DDC/3TC (3)
DDC/D4T/ABC (2)
DDI/DDC/D4T (2)


AZT/3TC/ABC/TDF (95)
AZT/DDI/D4T/3TC (43)
DDI/3TC/ABC/TDF (23)
AZT/DDI/3TC/ABC (15)
DDI/D4T/3TC/ABC (14)
AZT/D4T/3TC/TDF (12)
AZT/DDI/3TC/TDF (11)
AZT/D4T/3TC/ABC (9)
DDI/D4T/3TC/TDF (8)
D4T/3TC/ABC/TDF (8)
AZT/DDC/D4T/3TC (6)
AZT/ABC/FTC/TDF (5)
AZT/DDI/DDC/3TC (4)
3TC/ABC/FTC/TDF (3)
AZT/DDC/3TC/ABC (2)
AZT/3TC/FTC/TDF (2)


AZT/DDI/D4T/3TC/ABC (7)
AZT/DDI/DDC/D4T/3TC (7)
DDI/D4T/3TC/ABC/TDF (4)
AZT/DDI/3TC/ABC/TDF (4)

EFV (10,614)
NVP (8,262)
ETR (260)
DLV (209)
RPV (202)		LPVr (3,477)
NFV (2,643)
IDV (2,521)
ATVr (1,091)
SQV (999)
SQVr (853)
RTV (702)
DRVr (661)
IDVr (428)
ATV (334)
APV (270)
APVr (261)
DRV (75)
TPVr (64)

NFV/SQV (217)
APV/LPVr (87)
NFV/IDV (54)
IDV/SQV (54)
LPVr/SQV (47)
IDV/LPVr (38)
LPVr/ATV (37)
NFV/RTV (32)
NFV/LPVr (29)
NFV/APV (16)
APV/SQV (13)
APV/IDV (7)
NFV/ATV (6)
IDV/ATV (4)
LPVr/DRV (2)
SQV/ATV (2)
LPVr/TPV (2)
ATV/DRV (2)


RTV/LPVr/ATV (36)
RTV/APV/SQV (27)
NFV/RTV/SQV (20)
RTV/APV/ATV (17)
RTV/LPVr/SQV (16)
RTV/IDV/SQV (14)
NFV/RTV/IDV (12)
IDV/LPVr/ATV (11)
RTV/APV/LPVr (10)
NFV/LPVr/SQV (9)
RTV/IDV/ATV (9)
NFV/IDV/LPVr (9)
RTV/IDV/LPVr (9)
IDV/LPVr/SQV (6)
RTV/SQV/ATV (6)
NFV/IDV/SQV (5)
NFV/LPVr/ATV (5)
NFV/RTV/ATV (5)
RTV/ATV/DRV (5)
RTV/APV/IDV (3)
RTV/APV/DRV (2)


NFV/RTV/LPVr/ATV (15)
RTV/IDV/LPVr/ATV (9)
NFV/RTV/IDV/SQV (6)
RTV/APV/LPVr/SQV (4)
NFV/IDV/LPVr/SQV (4)
NFV/IDV/LPVr/ATV (3)
NFV/RTV/IDV/ATV (3)
RTV/IDV/LPVr/SQV (3)
RTV/APV/LPVr/ATV (2)
RTV/IDV/LPVr/DRV (2)


NFV/RTV/IDV/LPVr/ATV (6)
RTV/IDV/LPVr/SQV/ATV (2)
3TC/TDF/EFV (2,869)
D4T/3TC/EFV (2,603)
D4T/3TC/NVP (2,422)
AZT/3TC/NVP (2,340)
AZT/3TC/EFV (1,844)
FTC/TDF/EFV (1,535)
AZT/3TC/IDV (1,127)
3TC/TDF/NVP (788)
D4T/3TC/IDV (778)
AZT/3TC/LPVr (750)
AZT/3TC/NFV (738)
D4T/3TC/NFV (701)
3TC/ABC/EFV (494)
D4T/3TC/LPVr (490)
FTC/TDF/ATVr (462)
DDI/D4T/NFV (367)
AZT/3TC/SQV (361)
3TC/TDF/LPVr (361)
DDI/D4T/EFV (320)
3TC/ABC/LPVr (312)
FTC/TDF/DRVr (312)
FTC/TDF/NVP (306)
FTC/TDF/LPVr (294)
DDI/D4T/NVP (242)
D4T/3TC/SQV (227)
AZT/DDI/LPVr (223)
AZT/3TC/RTV (204)
D4T/3TC/SQVr (192)
D4T/3TC/RTV (188)
3TC/TDF/ATVr (158)
DDI/D4T/IDV (148)
AZT/DDI/NVP (139)
FTC/TDF/RPV (139)
3TC/ABC/ATVr (134)
AZT/3TC/SQVr (133)
DDI/D4T/SQVr (127)
AZT/3TC/TDF/LPVr (118)
AZT/3TC/ABC/EFV (118)
AZT/DDC/SQV (117)
AZT/3TC/IDVr (113)
D4T/NFV/NVP (110)
DDI/FTC/ATV (97)
D4T/3TC/IDVr (83)
DDI/D4T/LPVr (79)
3TC/ABC/NVP (79)
AZT/D4T/3TC/NVP/EFV (78)
DDI/3TC/EFV (77)
D4T/3TC/NFV/NVP (75)
DDI/D4T/NFV/EFV (70)
AZT/DDI/EFV (68)
AZT/3TC/ATVr (68)
AZT/DDI/NFV (65)
FTC/TDF/DRVr/ETR (62)
AZT/3TC/ABC/LPVr (62)
AZT/3TC/ATV (60)
AZT/DDI/3TC/LPVr (60)
AZT/DDI/IDV (60)
DDI/D4T/SQV (56)
AZT/DDI/SQV (55)
DDI/TDF/EFV (54)
D4T/SQVr (54)
DDI/D4T/NFV/NVP (51)
AZT/3TC/NFV/EFV (50)
DDI/3TC/IDV (50)
AZT/DDC/IDV (49)
DDI/D4T/RTV (48)
D4T/ABC/EFV (48)
DDI/ABC/LPVr (46)
DDI/D4T/IDVr (45)
DDI/3TC/LPVr (43)
3TC/ABC/TDF/ATVr (43)
AZT/3TC/NFV/NVP (42)
D4T/IDV (42)
AZT/DDI/RTV (40)
AZT/3TC/ABC/NVP (40)
AZT/3TC/TDF/NVP/EFV (40)
DDI/TDF/LPVr (40)
DDI/3TC/NFV (38)
DDI/NFV/NVP (37)
DDI/TDF/ATVr (36)
AZT/3TC/ABC/NFV (36)
3TC/ABC/TDF/LPVr (35)
DDI/3TC/NVP (35)
D4T/3TC/NFV/SQV (35)
D4T/NFV (34)
AZT/3TC/APV (34)
DDI/SQVr (33)
FTC/TDF/APVr (33)
AZT/SQV (33)
3TC/ABC/NFV (32)
3TC/TDF/DRVr (32)
AZT/3TC/TDF/EFV (32)
D4T/RTV/NVP (31)
DDC/SQV (31)
D4T/NFV/EFV (31)
Genotype-Phenotype
Number of isolates according to phenotype method and drug resistance mutation1
Method2NRTINNRTIPIINI
WTMTTotalWTMTTotalWTMTTotalWTMTTotal
PhenoSense5172,1002,6179671,8002,7679761,7272,7036505151,165
Antivirogram1661,0111,1774711,2161,6872951,1391,43412483207
Others5754660311357668986279365208626834
1 Phenotypic resistance test results are available for 16,248 isolates including 13,429 clinical isolates and 2,819 lab isolates; for each ARV drug class, the number of isolates are shown in WT (wildtype) and MT (mutants) isolates; WT genotypes are defined as lacking any of major drug resistance mutations (DRMs) listed here: PI-associated DRMs for PI, NRTI-associated for NRTI, NNRTI-associated for NNRTI and INI-associated DRMs for INI.
2 PhenoSense - Monogram, South San Francisco; Antivirogram - Virco, Belgium;
Appendixes: HIV-1 Group M virus
Number of virus samples according to geographical region and subtype
ContinentRegionsSubtypes
Africa
(n = 74,080)		South Africa (20,505), Uganda (12,157), Kenya (6,860), Cameroon (5,909), Ethiopia (2,825), Nigeria (2,801), Tanzania (2,727), Botswana (1,889), Zambia (1,674), Zimbabwe (1,556), Malawi (1,201), Togo (1,035), Senegal (1,027), Mozambique (969), DRC (879), Cote d'Ivoire (804), Morocco (791), Mali (756), Ghana (696), Burkina Faso (645), Angola (641), Gabon (620), Benin (554), Rwanda (488), Africa (470), Algeria (450), Burundi (417), Central African Republic (348), Congo-Brazzaville (304), Madagascar (261), Guinea-Bissau (223), Liberia (216), Chad (212), Niger (209), Tunisia (196), Guinea (191), Cape Verde (129), Equatorial Guinea (94), Swaziland (68), Mauritania (67), Sudan (60), Gambia (48), Seychelles (42), Libya (36), Zaire (20), Dijibouti (6), Somalia (4)C (33,179), A (13,311), CRF02_AG (10,363), D (6,496), G (2,532), B (2,274), A1 (959), CRF06_cpx (555), CRF01_AE (555), F (459), HIV-2 Group A (373), CRF45_cpx (329), J (264), Unknown (247), CRF18_cpx (224), CRF11_cpx (207), CRF35_AD (205), CRF09_cpx (184), H (154), A + G (93), A1D (92), CRF05_DF (87), HIV-2 Group B (80), CRF10_CD (78), CRF13_cpx (71), A1C (61), G + J (40), K (36), A + D (29), A3 (27), Group A (25), U (24), CRF49_cpx (22), A + J (22), CRF37_cpx (19), C + D (19), CRF25_cpx (16), A1G (15), CRF22_01A1 (15), CD (15), BD (14), HIV-2 CRF01_AB (14), A2D (13), CRF69_01B (13), CRF11A1 (13), AG (12), B + F (11), G + Unknown (11), CRF04_cpx (9), CRF43_02G (8), A1CD (8), A1 + G (8), A8 (7), A + CRF02_AG (7), A1 + D (7), CRF36_cpx (7), G + CRF02_AG (6), CRF26_AU (6), A6 (6), CRF03_AB (5), B + C (5), CRF12_BF (5), CRF02A3 (4), CRF07_BC (4), CRF63_02A1 (4), CRF21_A2D (4), CRF09U (3), CRF27_cpx (3), A1 + J (3), CRF44_BF (3), AD (3), CRF56_cpx (3), G + H + J (3), CG (3), CRF02A1 (3), B + CRF01_AE (3), CU (3), CRF34_01B (3), CRF37A (3), FK (2), A1DG (2), CRF0206 (2), A7 (2), CRF01A1 (2), CRF02U (2), CRF68_01B (2), CRF29_BF (2), A2CD (2), DU (2), A4 (2), A2G (2), CRF0209 (2), CRF06G (2), A1A2D (2), CRF01G (2), CRF09A1 (2), CRF09A1D (1), CRF0102 (1), HIV-2 Group H (1), CRF02G (1), HIV-2 Group I (1), CRF02D (1), CF1U (1), AU (1), A/D (1), CRF01F2 (1), CRF0109 (1), CRF78_cpx (1), A1B (1), ACFG (1), A2U (1), CRF20_BG (1), CRF08_BC (1), B + C + CRF01_AE (1), HIV-2 Group D (1), A1F1 (1), AJ (1), Group B (1), CRF26C (1), GU (1), CRF0102A1 (1), A1U (1), CRF01U (1), AGU (1), A1BD (1), AGHU (1), CRF47_BF (1), FKU (1), B + CRF02_AG (1), DG (1), F2K (1), HIV-2 Group G (1), CRF14_BG (1), GH (1), BC (1), A1A2G (1)
Asia
(n = 93,966)		China (51,298), Japan (10,882), India (6,532), Thailand (6,123), Vietnam (4,442), Israel (2,353), Taiwan (1,724), Cambodia (1,325), Korea (1,111), Malaysia (1,029), Pakistan (956), Indonesia (871), Uzbekistan (777), Hong Kong (609), Philippines (551), Republic Of Georgia (523), Iran (487), Singapore (388), Armenia (365), Kazakhstan (268), Myanmar (191), Tajikistan (174), Kuwait (152), Kyrgyzstan (137), Nepal (126), Mongolia (123), Saudi Arabia (120), Bangladesh (120), Sri Lanka (86), Laos (61), Lebanon (26), Yemen (19), Afghanistan (15), Turkey (2)CRF01_AE (35,565), B (24,763), C (11,133), CRF07_BC (5,818), B + C (5,208), A (2,996), CRF08_BC (1,477), CRF55_01B (1,446), CRF02_AG (1,216), A1 (742), B + CRF01_AE (482), BC (472), Unknown (465), CRF35_AD (436), CRF63_02A1 (224), D (224), CRF33_01B (189), G (171), A + CRF02_AG (146), CRF85_BC (93), CRF68_01B (84), CRF67_01B (68), F (44), HIV-2 Group A (40), CRF74_01B (31), CRF59_01B (29), CRF06_cpx (28), A2 + D (26), CRF03_AB (23), CRF12_BF (23), CRF52_01B (18), CRF45_cpx (18), A1 + G (16), A6 (16), CRF69_01B (16), CRF35_A1D (13), CRF62_BC (12), CRF10_CD (12), CRF83_cpx (12), CRF82_cpx (10), A + B (8), CRF56_cpx (8), CRF01C (8), A1 + D (7), B + F (7), B + C + CRF01_AE (7), CRF34_01B (6), CRF36_cpx (6), CRF64_BC (6), CRF05_DF (6), CRF24_BG (5), CRF09_cpx (5), CRF01B (5), CRF01BC (4), CRF65_cpx (4), G + CRF02_AG (4), A + D (4), H (3), CRF11_cpx (3), CRF18_cpx (3), HIV-2 CRF01_AB (3), B + G (3), CRF25_cpx (3), CRF43_02G (3), CRF78_cpx (3), B + CRF02_AG (2), CRF57_BC (2), HIV-2 Group B (2), A1C (2), CRF58_01B (2), BF1 (2), G + J (2), CRF61_BC (2), A1 + J (2), CRF96_cpx (1), CRF79_0107 (1), K (1), CRF16_A2D (1), G + Unknown (1), CRF48_01B (1), J (1), CRF22_01A1 (1), CRF0107 (1), CRF53_01B (1), CRF29_BF (1), CRF44_BF (1), CRF20_BG (1), CRF13_cpx (1), CRF28_BF (1), CRF0708 (1), A1G (1), A6 + B (1), A3 (1)
Central America
(n = 8,306)		Mexico (2,305), Puerto Rico (1,994), Cuba (1,514), Honduras (658), Panama (631), Dominican Republic (277), El Salvador (230), Haiti (229), Jamaica (220), Barbados (80), Guatemala (66), Trinidad (63), Belize (11), Antigua (8), Saint Vincent (6), Saint Lucia (5), Grenada (4), Dominica (3), Martinique (1), Montserrat (1)B (7,272), D (403), G (229), CRF18_cpx (118), C (79), CRF19_cpx (62), CRF20_BG (28), Unknown (17), H (16), CRF02_AG (15), A (14), F (13), CRF45_cpx (8), CRF24_BG (7), CRF01_AE (6), CRF12_BF (4), B + F (3), J (2), CRF23_BG (2), CRF05_DF (1), B + G (1), CRF04_cpx (1), CRF35_AD (1), CRF06_cpx (1), K (1), A + G (1), HIV-2 Group A (1)
Europe
(n = 70,656)		Italy (10,037), Spain (9,419), Germany (8,729), U.K. (7,281), France (6,082), Russia (5,403), Portugal (3,054), Belgium (2,823), Greece (2,665), Denmark (1,698), Poland (1,475), Sweden (1,265), Romania (1,241), Ukraine (1,229), Switzerland (1,041), Ireland (927), Estonia (910), Croatia (809), Cyprus (636), Slovenia (466), Luxembourg (441), Austria (436), Bulgaria (388), Europe (324), Netherlands (280), Hungary (198), Czech Republic (193), Serbia (187), Belarus (167), Azerbaijan (136), Norway (134), Finland (117), Republic of Latvia (117), Greenland (75), Latvia (72), Albania (66), Lithuania (38), Yugoslavia (33), Montenegro (32), Slovakia (26), Moldova (6)B (43,585), A (7,986), CRF02_AG (4,495), C (3,550), G (2,832), F (2,357), CRF01_AE (1,173), CRF06_cpx (774), HIV-2 Group A (574), A6 (541), D (533), CRF12_BF (227), A1 (206), CRF63_02A1 (141), A6 + B (138), Group A (102), CRF45_cpx (96), B + F (87), CRF11_cpx (84), CRF09_cpx (71), CRF18_cpx (66), CRF19_cpx (64), Unknown (59), H (53), HIV-2 Group B (53), J (53), CRF05_DF (49), CRF35_AD (48), CRF03_A6B (45), A + CRF02_AG (40), B + G (33), B + CRF02_AG (33), A6 + CRF02_AG (31), CRF04_cpx (29), B + C (28), CRF63_02A6 (28), CRF47_BF (26), CRF60_BC (24), CRF20_BG (23), CRF49_cpx (19), CRF13_cpx (18), A3 (18), A + G (18), CRF25_cpx (18), CRF03_AB (16), A + B (15), A1B (14), CRF24_BG (13), U (12), CRF50_A1D (10), G + J (9), K (8), A + J (8), CRF69_01B (7), CRF56_cpx (6), CRF43_02G (6), A1D (6), HIV-2 CRF01_AB (6), BD (5), CRF07_BC (5), CRF29_BF (5), CRF38_BF (4), A7 (4), A1 + J (4), CRF36_cpx (4), BC (4), CRF17_BF (4), CRF22_01A1 (4), CRF44_BF (3), CRF27_cpx (3), CRF37_cpx (3), G + Unknown (3), B + CRF01_AE (3), Group B (3), CRF10_CD (2), A + D (2), G + CRF02_AG (2), A1G (2), HIV-2 Group H (2), A1 + D (2), D/B (1), CRF0622 (1), CRF28_BF (1), CRF08_BC (1), A8 (1), CRF06A6 (1), CRF74_01B (1), F2G (1), CRF82_cpx (1), CRF42_BF (1), CRF14_BG (1), CRF55_01B (1), ABD (1), A1 + G (1), CRF52_01B (1), CRF31_BC (1), G + H + J (1), Group H (1), A + G (1)
Latin America
(n = 2)		Latin America (2)B (2)
North America
(n = 57,279)		U.S. (50,530), Canada (6,749)B (54,233), C (1,147), CRF02_AG (474), A (461), CRF01_AE (276), D (198), G (131), Unknown (129), F (54), CRF05_DF (21), CRF12_BF (21), CRF45_cpx (18), CRF06_cpx (15), H (12), J (10), CRF18_cpx (10), B + F (8), CRF24_BG (7), A1 (7), G + J (6), CRF07_BC (5), CRF09_cpx (5), U (4), A + D (3), CRF20_BG (3), G + CRF02_AG (2), CRF28_BF (2), B + C (2), CRF35_AD (2), CRF13_cpx (2), CRF11_cpx (1), CRF03_AB (1), CRF44_BF (1), CRF52_01B (1), B + G (1), CRF25_cpx (1), CRF74_01B (1), HIV-2 CRF01_AB (1), A2C (1), A1C (1), HIV-2 Group E (1)
Oceania
(n = 12,613)		Australia (12,122), Papua New Guinea (438), Fiji (53)B (8,665), C (1,660), CRF01_AE (1,532), CRF02_AG (184), Unknown (133), A (132), D (54), A1 (51), G (46), CRF07_BC (28), B + C (24), B + F (17), B + CRF01_AE (15), F (14), CRF12_BF (13), CRF06_cpx (5), A6 (5), CRF35_AD (5), CRF50_A1D (4), CRF59_01B (3), CRF33_01B (3), CRF60_BC (2), CRF24_BG (2), CRF18_cpx (2), CRF51_01B (2), CRF08_BC (2), CRF55_01B (1), B + CRF02_AG (1), B + G (1), CRF05_DF (1), CRF74_01B (1), A6C (1), CRF45_cpx (1), CRF77_cpx (1), CRF35_A1D (1), B + C + CRF01_AE (1)
South America
(n = 30,425)		Brazil (23,374), Argentina (4,286), Peru (1,698), French Guiana (304), Venezuela (281), Chile (210), Suriname (105), Colombia (85), Ecuador (58), Uruguay (13), Guyana (6), Bolivia (3), Paraguay (2)B (21,605), F (3,109), C (2,486), CRF12_BF (1,780), B + F (636), D (155), BF1 (82), A (76), CRF29_BF (70), CRF02_AG (66), B + C (54), CRF01_AE (48), CRF31_BC (40), CRF05_DF (36), CRF45_cpx (27), CRF28_BF (24), CRF38_BF (19), CRF44_BF (16), CRF17_BF (14), CRF40_BF (10), K (8), CRF69_01B (8), G (7), Unknown (6), CRF19_cpx (4), CRF42_BF (4), CRF47_BF (4), CRF06_cpx (3), CRF07_BC (3), CRF39_BF (3), J (3), CRF09_cpx (2), CRF35_AD (2), CRF60_BC (2), CRF11_cpx (2), CRF20_BG (1), BC (1), HIV-2 Group A (1), A2D (1), H (1), B + CRF02_AG (1), CRF71_BF (1), CRF89_BF1 (1), CF1 (1), CRF18_cpx (1), CRF04_cpx (1)

Mapping CRF subtypes from viruses to each genes
CRFsNo. virusesMapped subtype
proteaseRTintegrase
CRF01_AE14,277CRF01_AE (11,171)CRF01_AE (13,103)CRF01_AE (995)
CRF02_AG7,172CRF02_AG (5,883)CRF02_AG (5,653)CRF02_AG (690)
CRF03_AB16A (15)B (15)B (3)
CRF04_cpx25CRF04_cpx (15)CRF04_cpx (16)CRF04_cpx (5)
CRF05_DF23CRF05_DF (23)CRF05_DF (21)CRF05_DF (3)
CRF06_cpx821CRF06_cpx (647)CRF06_cpx (585)CRF06_cpx (115)
CRF07_BC1,146B (1,138)CRF07_BC (1,146)C (49)
CRF08_BC411C (408)CRF08_BC (411)C (21)
CRF09_cpx74CRF09_cpx (59)CRF09_cpx (59)CRF09_cpx (11)
CRF10_CD88D (55)CRF10_CD (87)CRF10_CD (5)
CRF11_cpx212CRF11_cpx (191)CRF11_cpx (169)CRF11_cpx (24)
CRF12_BF506F (487)CRF12_BF (484)F (32)
CRF13_cpx61CRF13_cpx (56)CRF13_cpx (50)CRF13_cpx (10)
CRF14_BG25G (22)G (24)G (5)
CRF16_A2D5A (5)A (5)A (1)
CRF17_BF16CRF17_BF (16)CRF17_BF (16)F (7)
CRF18_cpx67CRF18_cpx (63)CRF18_cpx (59)CRF18_cpx (6)
CRF19_cpx84D (83)D (83)CRF19_cpx (4)
CRF20_BG27CRF20_BG (27)CRF20_BG (27)G (4)
CRF21_A2D3D (3)CRF21_A2D (3)A (3)
CRF22_01A125A (18)A (17)A (14)
CRF23_BG11CRF23_BG (11)CRF23_BG (11)G (2)
CRF24_BG25CRF24_BG (25)CRF24_BG (25)G (5)
CRF25_cpx9F (7)B (7)B (8)
CRF26_AU10F (10)CRF29_BF (10)F (4)
CRF27_cpx5CRF27_cpx (4)CRF27_cpx (5)CRF27_cpx (3)
CRF28_BF14F (14)B (14)B (2)
CRF29_BF11F (11)CRF29_BF (11)F (4)
CRF30_02061CRF30_0206 (1)CRF30_0206 (0)CRF30_0206 (0)
CRF31_BC39C (38)CRF31_BC (39)C (5)
CRF33_01B76CRF33_01B (75)CRF33_01B (74)CRF01_AE (3)
CRF34_01B8B (8)CRF01_AE (8)CRF01_AE (4)
CRF35_AD53CRF35_AD (52)CRF35_AD (44)A (13)
CRF36_cpx2CRF36_cpx (2)CRF36_cpx (2)CRF36_cpx (2)
CRF37_cpx16G (14)CRF37_cpx (5)CRF37_cpx (4)
CRF38_BF14CRF38_BF1 (4)CRF38_BF1 (4)CRF38_BF1 (4)
CRF42_BF17CRF42_BF (17)CRF42_BF (17)CRF42_BF (17)
CRF43_02G20CRF43_02G (19)CRF43_02G (18)CRF43_02G (5)
CRF44_BF1CRF44_BF (1)CRF44_BF (1)CRF44_BF (1)
CRF45_cpx20CRF45_cpx (19)CRF45_cpx (18)CRF45_cpx (9)
CRF47_BF8CRF47_BF (8)CRF47_BF (8)CRF47_BF (5)
CRF49_cpx7CRF49_cpx (5)CRF49_cpx (5)CRF49_cpx (4)
CRF50_A1D1D (1)A (0)A (0)
CRF52_01B1CRF01_AE (1)CRF01_AE/B (1)CRF01_AE (0)
CRF54_01B10B (10)CRF53_01B (10)B (0)
CRF55_01B75CRF01_AE (74)CRF01_AE/B (75)CRF01_AE/B (1)
CRF56_cpx5CRF01_AE (5)CRF02_AG/B (5)CRF02_AG/B (1)
CRF58_01B4CRF01_AE (2)CRF01_AE/B (4)CRF01_AE/B (1)
CRF59_01B5CRF01_AE (5)CRF01_AE/B (5)CRF01_AE (1)
CRF60_BC1C (1)B/C (1)C (0)
CRF61_BC1C (1)B/C (1)C (1)
CRF62_BC1C (1)B/C (1)C (0)
CRF63_02A141CRF02_AG (41)CRF02_AG/A (41)CRF02_AG/A (37)
CRF64_BC1B/C (1)B/C (1)C (0)

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