Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Clinical Trial Datasets

ACTG A5142 clinical trial
Riddler SA, Haubrich R, DiRienzo AG, Peeples L, Powderly WG, Klingman KL, Garren KW, George T, Rooney JF, Brizz B, Lalloo UG, Murphy RL, Swindells S, Havlir D, Mellors JW; AIDS Clinical Trials Group Study A5142 Team. Class-sparing regimens for initial treatment of HIV-1 infection. N Engl J Med. 2008 May 15;358(20):2095-106.
PR Data in HIVDB
RT Data in HIVDB
Nucleotide sequences in fasta format
ACTGA5142_PR_fasta.txt,   ACTGA5142_RT_fasta.txt
Composite alignment (of sequences at baseline)
ACTGA5142_PR_composite.html,   ACTGA5142_RT_composite.html
List of sequences with stop codon, ambiguity codon and unusual residues
ACTGA5142_PR_QA.txt,   ACTGA5142_RT_QA.txt

Method: Direct PCR, Dideoxy terminator sequencing
Sample: Plasma
Timing: Multiple timepoints

Integrated view of ARV, genotypes, RNA and CD4 on 190 patients
Downloadable data files
Note on Dataset
Sixteen patients without RNA level provided where excluded from the data set. Changes are described in detail in ACTGA5142Dataset.txt.