Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Clinical Trial Datasets

ACTG 5257 clinical trial
Lennox JL, Landovitz RJ, Ribaudo HJ, Ofotokun I, Na LH, Godfrey C, Kuritzkes DR, Sagar M, Brown TT, Cohn SE, McComsey GA, Aweeka F, Fichtenbaum CJ, Presti RM, Koletar SL, Haas DW, Patterson KB, Benson CA, Baugh BP, Leavitt RY, Rooney JF, Seekins D, Currier JS; ACTG A5257 Team. Efficacy and tolerability of 3 nonnucleoside reverse transcriptase inhibitor-sparing antiretroviral regimens for treatment-naive volunteers infected with HIV-1: a randomized, controlled equivalence trial. Ann Intern Med. 2014 Oct 7;161(7):461-71
PR Data in HIVDB
RT Data in HIVDB
IN Data in HIVDB
Nucleotide sequences in fasta format
ACTG5257_PR_fasta.txt,   ACTG5257_RT_fasta.txt,   ACTG5257_IN_fasta.txt
Composite alignment (of sequences at baseline)
ACTG5257_PR_composite.html,   ACTG5257_RT_composite.html,   ACTG5257_IN_composite.html
List of sequences with stop codon, ambiguity codon and unusual residues
ACTG5257_PR_QA.txt,   ACTG5257_RT_QA.txt,   ACTG5257_IN_QA.txt

Method: Direct PCR, Dideoxy terminator sequencing
Sample: Plasma
Timing: Multiple timepoints

Integrated view of ARV, genotypes, RNA and CD4 on 415 patients
Downloadable data files