Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Lee EJ (2005)
Title Breast-milk shedding of drug-resistant HIV-1 subtype C in women exposed to single-dose nevirapine.
Citation J Infect Dis
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 47
NumPts 47
Subtype C

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
SA19_8w SA19_8w None NVP   V35T, E36A, T39E, S48T, S162C, K173A, D177E, T200A, E204K, Q207E, R211K, V245Q, A272S, K277R, E291D, V292I, T296TA, E302X  
SA22_8w SA22_8w None NVP   I135T, K166R, K173A, Q174K, D177E, S191ST, T200A, I202IV, Q207E, R211K, F214L, V245Q Q182K 
SA23_8w SA23_8w None NVP  K101KE K122E, D123NS, A158S, S162A, K173AV, Q174K, D177E, T200A, Q207K  
SA28_8w SA28_8w None NVP   V35T, E36A, T39E, S48T, K122E, D123N, T200A, Q207E, R211K, V245Q  
SA31_8w SA31_8w None NVP  V106VA V35T, E36A, T39E, E40D, S48T, V60I, K122KE, I135V, T165I, K173A, Q174K, D177E, T200A, Q207E, F214L, V245Q, A272P, K275Q, T286A, E291D  
SA32_8w SA32_8w None NVP   T39E, S48T, V60I, K122E, D123GS, T139TA, A158S, K173T, D177E, T200A, Q207E, V245K H96HN 
SA34_8w SA34_8w None NVP   T39KR, S48T, V60I, K122E, I135T, K173T, D177E, T200A, Q207E D123V 
SA36_8w SA36_8w None NVP   T39E, S48T, K122E, D123N, I142T, T200A, Q207E, R211K, V245Q S105S*, S117S* 
SA38_8w SA38_8w None NVP   T39E, S48T, V60I, K122E, D123G, I135V, K173A, Q174K, D177E, G196E, T200A, E204KQ, Q207E, R211RK, F214L, V245Q  
SA41_8w SA41_8w None NVP   T39E, S48T, S68SG, K122E, D123N, K166R, K173AT, Q174K, T200A, Q207E, R211K, F214L, I244IK, V245EQ H235HL 
SA42_8w SA42_8w None NVP   T39E, S48T, K122E, D123G, K166KR, K173T, D177E, I195L, T200A, Q207E, V245Q  
SA46_8w SA46_8w None NVP  K103KN T39E, S48T, V60I, K122KE, D123X, I135R, S162SN, S163ST, T165TI, K173A, Q174QR, D177E, I178IL, T200A, Q207E, R211RK, V245K  
SA51_8w SA51_8w None NVP   T39DE, S48T, K122E, D123G, S162C, K173A, Q174KT, D177DE, T200A, Q207E, R211RK, V245Q  
SA52_8w SA52_8w None NVP  K103KN T39E, S48T, V60I, K122E, D123G, K173A, D177E, I178M, T200A, Q207E, V245Q  
SA55_8w SA55_8w None NVP  Y188YC T39E, E40D, S48T, V60I, K122E, D123G, I135IV, S162A, K173A, D177E, T200A, Q207E, R211K, V245Q  
Zim11_8w Zim11_8w None NVP  K103KN, Y181YC T39E, S48T, K122E, D123G, S162CY, S163ST, T165TI, K173T, D177E, T200A, Q207E, R211RK, V245Q  
Zim14_8w Zim14_8w None NVP   T39E, S48T, K122E, D123N, I135IV, S162SC, K166R, K173A, D177E, E204EK, Q207AE, V245Q  
Zim15_8w Zim15_8w None NVP   T39DE, S48T, V60I, K122E, D123N, I135T, K173A, D177E, I178IM, T200A, Q207A, V245Q E42E* 
Zim16_8w Zim16_8w None NVP  V106VA, G190GA S48T, V60I, T69TS, W88WL, K101KN, K102X, K122E, D123G, P140PT, K173A, D177E, T200A, Q207E, V245K T39*E, E53EV, N81NY, H96HN, A98AT, G99GRS, L100L*S, R125RS, Q145QK, Q151Q* 
Zim17_8w Zim17_8w None NVP  E138A T39E, S48T, V118I, K122E, D123N, T139A, R172K, K173S, Q174K, T200A, Q207E, F214L, V245Q, E248D  
Zim19_8w Zim19_8w None NVP   T39E, S48T, K122E, D123G, K173T, Q174K, T200A, Q207E, R211K, V245Q  
Zim20_8w Zim20_8w None NVP  K103KN, V106VIM T39E, S48T, K122E, D123N, I135V, S162C, K173T, Q174K, D177E, I178L, T200A, E203X, Q207D, R211K, V245Q  
Zim21_8w Zim21_8w None NVP   T39E, S48T, D123N, K173V, D177E, G196R, T200A, Q207E, R211K, V245Q  
Zim22_8w Zim22_8w None NVP   T39E, S48T, K49KR, K122E, D123G, K173T, Q174K, D177E, T200A, Q207E, R211K, V245Q  
Zim23_8w Zim23_8w None NVP   T39E, S48T, K122E, D123G, I135IV, K173A, D177E, G196R, T200A, Q207E, V245Q  
Zim24_8w Zim24_8w None NVP  K103KN T39DE, E40ED, S48T, K122E, D123N, K173A, D177E, T200A, Q207E, R211K, V245Q, D250E  
Zim25_8w Zim25_8w None NVP   T39E, S48T, K122E, D123GS, K173A, D177E, T200A, Q207D, R211K, V245Q  
Zim26_8w Zim26_8w None NVP   T39E, S48T, K122E, D123N, I135IV, K173A, D177E, T200A, Q207E, R211K, V245Q  
Zim27_8w Zim27_8w None NVP  K103KN T39E, S48T, K122E, D123N, K173T, D177E, T200A, Q207E, V245M  
Zim28_8w Zim28_8w None NVP   T39E, S48ST, K122E, D123G, S162SC, K173A, D177E, I178IL, T200A, Q207E, R211RK, V245Q  
Zim30_8w Zim30_8w None NVP   T39E, E44K, I47IF, A62P, K122E, D123S, A129X, T139A, I142V, A158S, K166R, K173T, D177E, T200A, Q207E, R211T, V245K, D250E S117S*, F124FI 
Zim31_8w Zim31_8w None NVP  E138A T39E, S48T, E53ED, K122E, D123N, I142T, K173IM, Q174K, I178L, T200A, I202V, Q207E, R211K, F214FL, P243T, V245Q, E248D  
Zim33_8w Zim33_8w None NVP  Y181YC T39E, S48T, I135IMT, S162N, K173T, T200A, Q207E, R211K, V245C, D250E  
Zim34_8w Zim34_8w None NVP  K103KN V35T, E36A, T39E, S48T, V60I, K122E, D123S, I135V, S162C, K173T, Q174KR, D177E, T200A, Q207K, R211K, V245Q  
Zim35_8w Zim35_8w None NVP  K103KN S48T, K122E, D123G, I135R, K173T, D177E, T200A, Q207E, V245Q  
Zim37_8w Zim37_8w None NVP   V35T, E36A, T39E, S48T, V60VI, V90VI, K122E, D123S, I142IT, A158S, K173A, Q174R, D177E, I178IM, T200A, Q207EK, V245Q  
Zim38_8w Zim38_8w None NVP  K103KN, Y188YC T39E, S48T, E53ED, K122E, D123G, S162X, K173A, Q174K, D177E, I178L, T200A, Q207E, V245Q  
Zim39_8w Zim39_8w None NVP   V35T, T39EK, S48T, K122E, S162C, K173A, Q174R, D177E, T200A, Q207E, R211K, V245E, D250E  
Zim40_8w Zim40_8w None NVP   V35T, E36ED, T39K, S48T, A98AS, K122E, D123G, K173T, D177E, V189VI, Q197K, T200E, Q207A, V245Q  
Zim43_8w Zim43_8w None NVP   V35T, E36A, T39E, S48T, K122E, K173A, D177E, T200A, Q207G, R211K, V245Q  
Zim44_8w Zim44_8w None NVP   V35R, T39E, S48T, K122E, D123N, I135T, S162C, K173A, Q174K, D177E, T200A, Q207D, V245Q  
Zim45_8w Zim45_8w None NVP  K103KN, G190GA V35T, E36A, T39E, E40D, S48T, V60I, K64KR, K122E, D123S, K173A, D177E, T200A, Q207E, R211RK, V245Q  
Zim46_8w Zim46_8w None NVP  K103N T39E, S48T, K122E, D123DG, S162C, K173A, D177E, I178L, T200A, Q207E, R211K, V245Q  
Zim47_8w Zim47_8w None NVP   V35T, E36A, T39E, S48T, N57NK, K64KR, V90I, K122E, K173AT, D177E, I178M, T200A, Q207E, R211K, V245Q  
Zim48_8w Zim48_8w None NVP   V35T, E36A, T39E, S48T, K49R, N57NK, K102KR, D121Y, K122E, D123G, I135R, S162C, K173T, D177E, D192E, T200A, Q207E, R211K, V245Q L193L* 
Zim49_8w Zim49_8w None NVP   V35T, E36A, T39E, S48T, K173A, G196D, T200A, E204K, Q207E, F214FL, P243T, V245Q  
Zim50_8w Zim50_8w None NVP   V35T, E36A, T39E, S48T, K122E, K173A, Q174QR, D177E, I178IM, T200A, Q207E, V245Q