Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Pillay (2002)
Title HIV-1 subtype C reverse transcriptase sequences from drug-naive pregnant women in South Africa.
Citation ARHR
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 37
NumPts 37
Subtype C

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
00ZA_AC1 00ZA_AC1 None None   V35T, E36A, T39E, S48T, V118I, K122E, D123S, T165I, K166R, P176T, T200A, Q207E, F214L, V245L, A272P, Q278H, T286A, A288T, E291D, V292I, I293V  
00ZA_AC10 00ZA_AC10 None None   V35T, T39E, S48T, K122E, D123G, A158S, K173A, D177G, T200E, Q207K, R211K, V245L, E291D, V292I, I293V  
00ZA_AC11 00ZA_AC11 None None   E28K, E29R, I31ILV, V35T, E36A, T39E, I47X, S48T, K122E, D123N, T165I, K173A, Q174R, D177E, V179I, T200A, Q207E, F214L, V245Q, D250E, A272P, K277R, Q278H, K281R, R284K, T286A, E291D, V292I, I293V  
00ZA_AC12 00ZA_AC12 None None   K11R, K20R, V35T, E36A, T39E, S48T, K122E, D123S, K173A, D177E, T200A, Q207E, V245Q, K275Q, E291D, V292I, I293V V148A, C280G 
00ZA_AC13 00ZA_AC13 None None   V35T, E36A, T39E, S48T, V60I, K122E, D123G, A158S, K173A, Q174R, D177E, I178L, T200A, Q207D, R211K, P243T, V245Q, A272P, T286A, E291D, V292I, I293V  
00ZA_AC14 00ZA_AC14 None None   V35T, E36A, T39E, S48T, E53D, K122E, D123N, K173A, Q174K, D177E, T200A, Q207E, V245Q, A272Q, T286A, E291S, V292I, I293V, E297K  
00ZA_AC15 00ZA_AC15 None None   V35T, E36A, T39E, S48T, E53D, K122E, D123N, K173A, Q174K, D177E, T200A, Q207E, V245Q, A272Q, T286A, E291S, V292I, I293V, E297K  
00ZA_AC16 00ZA_AC16 None None   V35K, T39E, S48T, D121A, K122E, K173A, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, E291D, V292I  
00ZA_AC17 00ZA_AC17 None None   V35T, T39E, S48T, V60I, K122E, D123N, K166R, K173A, Q174K, D177E, T200A, Q207E, R211K, F214L, V245Q, A272P, K277R, T286A, E291D, V292I, I293V  
00ZA_AC19 00ZA_AC19 None None   V35T, E36A, T39E, S48T, K122E, K173A, D177E, I178V, T200A, Q207D, F214L, V245Q, E248D, A272P, K275R, Q278H, T286A, A288S, E291D, V292I, I293V, P294T, L295M  
00ZA_AC2 00ZA_AC2 None None   V35T, E36A, T39E, E40D, S48T, K122E, D123N, K173A, D177E, T200A, Q207E, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, K311R  
00ZA_AC20 00ZA_AC20 None None   V35M, E36A, T39E, S48T, D121C, K122E, S162C, K173A, D177E, T200A, E204D, R211K, V245K, A272P, T286V, E291D, V292I, I293V, E297K  
00ZA_AC24 00ZA_AC24 None None   K20R, V35T, E36A, T39E, S48T, K122E, D123N, K173A, Q174K, D177E, G196M, T200A, I202V, Q207E, R211K, V245K, D250E, A272P, L279M, T286A, E291D, V292I, I293V, E312Q  
00ZA_AC25 00ZA_AC25 None None   K20R, V35T, E36A, T39E, S48T, V60I, K122E, D123G, K173A, Q174K, D177E, I178L, T200A, Q207D, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, E312Q  
00ZA_AC26 00ZA_AC26 None None   V21I, V35T, E36A, T39E, S48T, V60I, K122E, D123G, I135V, T165I, K173A, Q174K, D177E, T200A, Q207A, R211K, V245Q, A272P, K277R, T286A, E291D, V292I  
00ZA_AC27 00ZA_AC27 None None   V35M, E36A, T39E, S48T, K122E, D123G, K173T, D177E, Q207G, V245Q, V254I, L260I, A272P, K277R, T286A, E291D, V292I, I293V  
00ZA_AC28 00ZA_AC28 None None   V10L, V35T, E36A, T39E, S48T, K122E, D123N, I135R, K173T, Q174R, I195T, T200A, Q207E, R211K, F214L, V245Q, S251N, A272P, I274V, Q278H, T286A, E291D, V292I, I293V  
00ZA_AC29 00ZA_AC29 None None   V35T, E36A, T39D, S48T, V60I, K122E, D123N, I135V, S162C, K173T, Q174K, D177E, T200A, I202V, Q207E, R211K, F214L, V245Q, D250E, A272P, T286A, E291D, V292I, I293V, E297A  
00ZA_AC3 00ZA_AC3 None None   V35T, E36A, T39E, E40D, S48T, K122E, D123N, K173A, D177E, T200A, Q207E, V245Q, A272P, K277R, T286A, E291D, V292I, I293V  
00ZA_AC31 00ZA_AC31 None None   V35T, E36A, T39E, E40D, S48T, K122E, K173A, D177E, T200A, Q207E, V245Q, D250N, A272P, K277R, L279I, T286A, E291D, V292I, I293V, K311R R125RS 
00ZA_AC34 00ZA_AC34 None None   V35T, E36A, T39E, S48T, K122E, D123G, K166R, K173A, D177E, T200A, Q207D, V245Q, K275Q, K277R, T286A, E291D, V292I, I293V  
00ZA_AC35 00ZA_AC35 None None   V35T, E36A, T39E, S48T, I135V, S162C, K173T, D177E, T200A, Q207E, V245Q, T286A, E291D, V292I, I293V  
00ZA_AC37 00ZA_AC37 None None   V35T, T39E, S48T, K122E, D123N, I135R, T165I, K173T, Q174R, T200A, Q207X, R211K, F214L, A272P, K277R, T286A, E291D, V292I, I293V  
00ZA_AC39 00ZA_AC39 None None   V35T, E36A, T39D, S48T, K122E, D123G, S162A, K173T, T200A, Q207G, R211K, V245M, D250E, A272P, K277R, T286A, E291D, V292I, I293V  
00ZA_AC4 00ZA_AC4 None None   V35T, E36A, T39E, S48T, V118I, K122E, D123N, T165I, K166R, K173T, Q174R, D177E, T200A, E203D, Q207E, R211K, F214L, V245L, A272P, K275Q, K277R, T286A, E291D, V292I, I293V, P294Q  
00ZA_AC44 00ZA_AC44 None None   V35T, T39K, E40D, S48T, K122E, D123G, S162C, K173A, Q174K, D177E, T200A, Q207E, V245Q, K277R, T286A, E291D, V292I, I293V A272N 
00ZA_AC45 00ZA_AC45 None None   V21I, V35T, E36A, T39E, S48T, V60I, A98S, K122A, I135V, K173A, Q174K, D177E, T200A, Q207A, P243S, V245Q, A272P, T286A, E291D, V292I, I293V  
00ZA_AC46 00ZA_AC46 None None   V35T, E36A, T39E, S48T, V60I, K122E, K173A, Q174K, D177E, I178M, T200A, Q207E, V245H, A272P, K277R, T286A, E291D, V292I, I293V  
00ZA_AC47 00ZA_AC47 None None   V35T, E36A, T39E, S48T, V60I, V118I, K122E, D123S, I135T, K173A, Q174K, D177E, T200A, Q207E, R211K, F214L, V245K, A272P, I274V, K277R, T286A, E291D, V292I, I293V  
00ZA_AC48 00ZA_AC48 None None   V35T, E36A, T39E, S48T, V60I, K122E, D123G, I135T, T165I, K173A, Q174K, D177E, I178L, T200A, Q207A, V245Q, A272S, K277R, T286A, E291D, E297K  
00ZA_AC49 00ZA_AC49 None None   V35T, E36A, T39E, E40D, S48T, V60I, K122E, D123G, K173A, D177E, V179I, T200A, Q207E, D218E, V245K, A272P, T286A, E291D, V292I, I293V  
00ZA_AC5 00ZA_AC5 None None   V35T, T39E, S48T, K122E, D123S, K173T, T200A, Q207K, V245H, D250E, A272K, T286A, E291D, V292I, I293V  
00ZA_AC52 00ZA_AC52 None None   V35T, T39E, S48T, V60I, K122E, D123G, I135V, K166R, K173A, Q174K, D177E, I195L, T200A, Q207A, R211K, F214L, V245Q, A272P, K277R, T286A, E291D, V292I, I293V  
00ZA_AC6 00ZA_AC6 None None   V35T, E36A, T39E, S48T, V60I, K122E, D123G, I135V, K173A, T200A, Q207E, V245K, A272P, K277R, T286A, E291D, V292I, I293V  
00ZA_AC7 00ZA_AC7 None None   V35T, E36A, T39E, S48T, V60I, K122E, D123G, K173A, Q174K, D177E, I178M, T200A, Q207D, V245K, A272P, K277R, T286A, E291D, V292I, I293V, E297K, A304E  
00ZA_AC8 00ZA_AC8 None None   V35T, E36A, T39E, S48T, V60I, D121Y, K122E, T139A, K173A, Q174K, D177E, T200A, Q207A, V245Q, A272P, T286A, E291D, V292I  
00ZA_AC9 00ZA_AC9 None None   V35T, E36A, T39E, S48T, K122E, D123S, S162A, K173A, D177E, T200A, E204Q, Q207D, R211K, P243T, V245Q, A272P, K275Q, K277R, T286A, E291D, V292I, I293V