Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Ariyoshi (2003)
Title Patterns of point mutations associated with antiretroviral drug treatment failure in CRF01_AE (subtype E) infection differ from subtype B infection.
Citation JAIDS
SelectedGene PR
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 57
NumPts 43
Subtype CRF01_AE, A

 

Clinical PR Isolates


SubjectIsolatePIsWksPIMajorPIMinorCommonUnusual
JPN1 JPN1 None    I13V, E35D, M36I, R41K, H69K, L89M  
JPN10 JPN10 None    I13V, E35D, M36I, R41K, L63P, H69K, L89M, F99FL  
JPN11 JPN11 IDV 75   I13V, K20KR, E35D, M36I, R41K, R57K, H69K, L89M  
JPN12 JPN12A SQV 77  Q58E I13V, K20I, E35D, M36I, R41K, H69K, V82I, L89M  
  JPN12B SQV 92  Q58E I13V, K20I, E35D, M36I, R41K, H69K, V82I, L89M  
JPN13 JPN13A None    I13V, M36I, R41K, H69K, L89M  
  JPN13B None    I13V, M36I, R41K, H69K, L89M  
JPN14 JPN14 NFV   K20R, E35D, M36I, R41K, K45R, H69X, L89M, I93L  
JPN15 JPN15 NFV, IDV 113 I54V, L90M L10F I13V, K20R, L33I, E35D, M36I, R41K, I64V, H69K, L89M  
JPN16 JPN16 None    L10LI, I13IV, E35D, M36I, R41K, R57RK, I62IV, H69K, V82VI, L89M  
JPN17 JPN17A IDV 68   I13V, E35D, M36I, R41K, H69K, L89M  
  JPN17B IDV 80   I13V, E35D, M36I, R41K, H69K, L89M W42WL, K45KE 
JPN18 JPN18 Unknown    I13V, G17E, K20R, E35D, M36I, R41RK, H69K, I72V, L89M  
JPN19 JPN19A NFV 59 N88S L10F, K20IT G16E, E35D, M36I, R41K, L63T, I64V, H69K, L89M, I93L  
  JPN19B NFV 77 N88S L10F G16E, K20I, E35D, M36I, R41K, L63T, I64V, H69K, L89M, I93L  
JPN20 JPN20 None    I13V, E35D, M36I, R41K, K45R, H69K, L89M  
JPN21 JPN21A IDV, NFV 124 M46I, N88S L10F, T74TP, L89V K20I, M36I, L63LP, H69K, I85V, I93L  
  JPN21B IDV, NFV 132 M46I, N88S L10F, L89V K20I, M36I, H69K, I85V, I93L  
JPN22 JPN22 NFV   I13V, E35D, M36I, R41K, H69K, L89M  
JPN23 JPN23 None    I13V, E35D, M36I, R41K, H69K, L89M Y59YC 
JPN24 JPN24 None   L33F T12S, I13V, M36I, N37D, R41K, H69K, K70R, L89M, I93L K45KE 
JPN25 JPN25 NFV 73 M46I, N88S L10F, K20T, Q58QE, L89V I13V, L33I, E35D, M36I, R41K, I62IV, H69K  
JPN26 JPN26 NFV, IDV 51   L10LI, K20R, E35D, M36I, R41K, H69K, L89M, I93L  
JPN27 JPN27A None    I13V, G17E, K20R, E35D, M36I, R41K, R57RK, I62IV, H69K, L89M  
  JPN27B None    I13V, G17E, K20R, E35D, M36I, R41K, I62V, H69K, L89M  
JPN28 JPN28 NFV 80 M46MI, N88S, L90LM L10LF, K20T, L89IMT I13V, E35D, M36I, R41K, H69K, K70R, A71AT  
JPN29 JPN29 None    E35D, M36I, N37NS, R41K, H69K, L89M  
JPN3 JPN3 IDV 56 V82VF  L10I, I13V, I15V, E35D, M36I, R41K, R57K, H69K, L89M  
JPN30 JPN30 NFV 71 L90M K20T L10V, I13V, E35D, M36I, R41K, H69K, K70R, T74S, L89I  
JPN31 JPN31 SQV, NFV 132  K20KT, N83D, L89IV L10LI, I13V, A22AV, L33LI, E35D, M36I, R41K, I62V, H69K  
JPN32 JPN32 NFV 116   L10LI, I13V, E35D, M36I, R41K, R57K, H69K, L89M  
JPN33 JPN33 NFV   I15IV, E35D, M36I, R41K, H69K, L89M, I93L  
JPN34 JPN34 IDV, SQV 76 G48V, I54IV L33LF, N83ND L10LI, I13V, I15V, E35D, M36I, R41K, L63P, H69K, L89M  
JPN35 JPN35 IDV, NFV 140 M46I, L90M K20T L10V, I13V, E35D, M36I, R41K, Q61H, L63P, I64V, H69K, K70R, T74S, L89M, I93L R87RKQ 
JPN36 JPN36 None    I13V, I15IV, E35D, M36I, R41K, L63PS, H69K, L89M  
JPN37 JPN37A IDV 45   I13V, E35D, M36I, R41K, H69K, L89M  
  JPN37B IDV, SQV, RTV 128   I13V, E35D, M36I, R41K, H69K, I72IV, L89M  
JPN38 JPN38 IDV, NFV 129 I54V, V82F  L10I, I13V, G16E, K20I, E35D, M36I, R41K, K45V, L63LH, H69K, K70R, L89M, F99FL  
JPN39 JPN39 NFV 200 M46I, N88S L10F I13V, K20I, E35D, M36I, R41RK, I64V, H69K, T74S, V77VI, L89M, I93L  
JPN4 JPN4 None    I13V, E35ED, M36I, R41K, H69K, L89M  
JPN40 JPN40A IDV, SQV, NFV 179  L10F T12A, I13V, I15V, E35D, M36I, R41K, R57K, I64V, H69K, L89M  
  JPN40B IDV, SQV, NFV 218  L10LF T12A, I13V, I15IV, E35D, M36I, R41K, R57K, I64IV, H69K, L89M  
JPN41 JPN41A IDV, SQV, NFV 125 G48ST, I54V, V82F, L90M  L10I, I13V, G16E, K20I, E35D, M36I, P39Q, R41K, K45V, I62V, L63P, H69K, L89M  
  JPN41B IDV, SQV, NFV, APV 195 I54V, V82F, L90LM  L10I, I13V, G16E, K20I, E35DN, M36I, P39Q, R41K, K45V, G48X, I62V, L63P, H69K, L89M  
JPN42 JPN42A SQV 104 I54V, V82F, L90M L33F L10V, I13V, I15IV, G16E, K20I, E35D, M36I, N37ND, R41K, H69K, T74S, L89I, Q92K I84L 
  JPN42B SQV, RTV, APV 164 I54IV, V82VF, L90LM  L10LV, I13V, G16E, K20KI, L33I, E35D, M36I, N37ND, R41K, H69K, T74TS, L89IM, Q92K I84IL 
JPN43 JPN43A None    I13V, I15V, E35D, M36I, R41K, H69KQ, L89M  
  JPN43B NFV 67 M46MI, L90LM L10LF, K20T, L89IMV I13V, I15V, E35D, M36I, R41K, H69K, A71AT, T74TS, I93IL  
JPN44 JPN44A IDV, SQV, RTV 88   K20R, E35D, M36I, N37D, L63P, H69K, L89M, I93L  
  JPN44B IDV, SQV, RTV, LPV 204   K20R, E35D, M36I, N37D, L63P, H69K, L89M, I93L  
JPN45 JPN45A IDV 64 N88S L10F, K20T, L89V I13V, L33LI, E35D, M36I, R41K, I62IV, L63P, H69K, A71AT, T74TS  
  JPN45B IDV, APV, LPV 68 N88S L10F, K20T, L89V I13V, E35D, M36I, P39PS, R41K, L63P, H69K, A71T  
JPN5 JPN5 None    I13V, E35D, M36I, R41K, H69K, L89M  
JPN6 JPN6 NFV  L24LI I13V, I15V, E35D, M36I, R41K, H69K, L89M  
JPN7 JPN7 NFV   L10I, I13V, E35D, M36I, G40GR, R41K, H69K, I72V, L89M  
JPN9 JPN9A None    K20IR, D25DH, E35D, M36I, R41K, I62MT, L63P, H69K, L89M G16G* 
  JPN9B None  M46ML  K20R, E35D, M36I, R41K, I62MT, L63P, H69K, L89M K45KE