Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Dunne (2001)
Title Comparison of genotyping and phenotyping methods for determining susceptibility of HIV-1 to antiretroviral drugs.
Citation AIDS
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 17
NumPts 17
Subtype B

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
ALD-pt1 ALD-pt1 NRTI NNRTI M41L, D67E, T69S_SG, K70R, V75M, T215Y E138A, G190Q K122KE, I135T, P157PA, S162CY, P170PL, H208Y, R211K, A272P, K277R, V317A  
ALD-pt10 ALD-pt10 NRTI NNRTI M184MV  K20R, A98S, K122E, R211G, V245E, S251Q K287KE 
ALD-pt11 ALD-pt11 NRTI NNRTI M41L, M184V, L210LW, T215Y  K122KE, K173Q, R211K, K238R, V245T, A272P, K277R, T286A, E297K  
ALD-pt12 ALD-pt12 NRTI NNRTI   K104KR, K122Q, D123N, I135L, S162C, V179I, R211RK, V245I, A272S, A288S, I293V  
ALD-pt13 ALD-pt13 NRTI NNRTI L210W, T215Y  K20R, R83K, V118VI, I135V, G196E, E203K, Q207E, R211K, A272P, K277R, I293IV, E297K  
ALD-pt14 ALD-pt14 NRTI NNRTI M41L, A62AV, M184V, T215Y  E44D, D123E, K166R, D177E, Q207A, R211S, A272P, K277R, A288S, I293V, E297K  
ALD-pt15 ALD-pt15 NRTI NNRTI M41L, M184V, T215Y  S68G, K122P, I135L, K166R, D177E, I178L, V179I, T200A, R211K, K277R, T286A, A288S, E297EA  
ALD-pt16 ALD-pt16 NRTI NNRTI M41L, D67N, M184V, L210W, T215Y  V35VI, A98S, K122KE, I135T, E203K, Q207E, R211RK, V245T, A272P, K277R, I293V, E297K  
ALD-pt17 ALD-pt17 NRTI NNRTI M41L, D67N, V75M, L210W, T215Y K103N, Y181C, H221Y V21I, E28K, K32E, T39K, K43E, E44D, V60I, V111I, V118I, I142V, S162C, I178L, V179I, G196E, E203D, E204Q, H208Y, R211K, V245T, A288S, I293V, E297K, E312EQ  
ALD-pt18 ALD-pt18 NRTI NNRTI M41L, D67N, L74LI, V75VA, M184V, L210W, T215Y G190GA, H221HY T39A, K43E, E44D, R83K, K102Q, K103X, V118I, K122E, S162Y, D177E, E203D, H208Y, R211K, V245E, T286A, E297K  
ALD-pt2 ALD-pt2 NRTI NNRTI   Q197K, Q207E, R211K, L283I, I293V, E297K, E312A  
ALD-pt3 ALD-pt3 NRTI NNRTI T215Y K103N D123E, I135V, Q197E, Q207A, R211K, V245KN, L283I, A288AP, I293V, P294A, E297K  
ALD-pt5 ALD-pt5 NRTI NNRTI  K103N R83K, D177E, I178LM, T200TA, Q207E, R211K, V245K, K249Q, I293IV, V317A  
ALD-pt6 ALD-pt6 NRTI NNRTI M41L, M184V, L210W, T215Y  V35T, T200A, R206RK, R211RK, K277R, T286TA, I293V, E297K  
ALD-pt7 ALD-pt7 NRTI NNRTI M41L, D67N, K70R, T215F, K219Q Y188L V35T, T39K, K43E, V60I, T69N, K102Q, L109LI, K122E, D123N, Q151X, K166R, G196E, I202V, L210F, A272P, K277R, E297K  
ALD-pt8 ALD-pt8 NRTI NNRTI M41L, D67N, K70R, V75M, M184V, T215Y G190A S3C, E6K, K43E, E44A, N54NI, K122E, S162C, E169D, A272P, K277R, V317A  
ALD-pt9 ALD-pt9 NRTI NNRTI M41L, D67N, K70R, L74I, V75S, M184V, T215F, K219Q  V35I, T39A, T69E, V118I, K122E, D123DN, I135T, S162D, V179VI, I202IV, F214L, K223Q, L228H, Q278H, I293V