Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Hoelscher (2001)
Title High proportion of unrelated HIV-1 intersubtype recombinants in the Mbeya region of southwest Tanzania.
Citation AIDS
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 9
NumPts 9
Subtype C, A

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
97TZ01 97TZ01 None None   V35T, E36A, T39E, S48T, K122E, I135T, S162C, K173A, D177E, G196R, T200A, I202V, Q207E, R211K, V245Q, A272K, K277R, T286A, E291D, V292I, I293V, Q334H, G335D, R356K, G359T, T377L, K390R, E404D, V435A, N447S, V466I, S468T, D471E, H483Q, L491S, S519N, A534S, A554S  
97TZ02 97TZ02 None None   V35T, V60I, K122E, I135T, K173L, Q174K, D177E, V179I, Q207A, R211S, V245E, D250E, K281R, T286A, E291A, V292I, I293V, P294T, E312N, G335D, M357K, G359S, T369A, A371V, I375V, A376V, A400T, T403M, E404D, E413D, E432D, S468P, D471E, Q480H, H483Y, L491S, Q507H, K512R, S519N, Q524K, K527E, E529D, A534S, A554S  
97TZ03 97TZ03 None None   V35T, V60I, K122E, D123S, I135T, T139L, L149P, K173A, Q174K, D177E, T200A, Q207A, R211S, D250E, A272P, T286A, E291D, V292I, I293V, P294T, E312D, Y318*, D320G, G335D, M357K, G359S, T369A, A371V, I375V, A376V, T377L, A400T, T403M, E404D, E432D, E449K, D471E, Q480H, H483Y, L491P, K512R, S515A, S519N, Q524K, K527G, E529D, L533P, A534S, A554S  
97TZ04 97TZ04 None None   V35T, E36A, T39E, S48T, K122E, I135T, K154E, S162C, R172G, K173A, Q174R, D177E, Q197K, T200A, I202V, Q207E, P243T, V245Q, A272P, K275R, T286A, E291D, V292I, I293V, P294T, Q334H, G335D, R356K, G359T, T377M, K390R, A400T, E404D, E413D, L452V, V466I, S468T, T470A, D471E, H483Q, L491S, S519N, A534S, A554S P387S 
97TZ05 97TZ05 None None   E6EK, K20R, T39E, S48T, K102R, K122E, D123N, I135T, S162C, K173A, D177E, T200V, Q207D, R211K, V245Q, E248D, A272P, K277R, E291D, V292I, I293V, R307K, K311R, D324E, Q334H, G335D, R356K, G359T, T377M, K390R, A400T, E404D, L452I, V466I, D471E, H483Q, L491S, S519N, K527N, K530R, A534S, V548I, A554S  
97TZ06 97TZ06 None None   V35T, E36A, T39E, S48T, D121H, K122E, D123S, S162C, I178L, T200A, Q207G, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, E297K, E308K, Q334D, G335D, R356K, G359T, T377M, I382V, K390R, E396D, A400T, E404D, V435M, K465R, V466I, V467I, D471E, H483Q, L491P, S519N, K530R, A534S, A554S  
97TZ07 97TZ07 None None   V35T, E36A, T39D, S48T, V90I, K104R, K122E, D123S, A158S, K173A, D177E, T200A, Q207E, V245L, D250E, A272P, K275R, Q278Y, T286A, E291D, V292I, I293V, P294T, Q334H, G335D, R356K, G359T, A371T, T377M, T386I, K390R, A400T, E404D, E432D, V435A, L452I, D471E, H483Q, L491S, L517I, S519N, K530R, A534S, A554S  
97TZ08 97TZ08 None None   L34I, V35T, K49R, V60I, K122E, I142L, K173A, T200A, Q207E, V245Q, E248D, D250E, A272S, K277R, T286A, E291D, V292I, I293V, V317A, G335D, F346H, R356K, R358K, G359T, A376S, T377H, S379C, K390R, A400T, E404D, E432D, V435I, L469I, T470S, Q480H, H483Y, L491S, S519N, I526V, K530R, A534S, A554S  
97TZ09 97TZ09 None None   E6K, V35T, E36A, T39E, S48T, K122E, D123S, I135T, S162C, K173A, D177E, T200A, Q207A, R211K, V245Q, A272P, I274V, T286A, E291D, V292I, I293V, Q334H, G335D, K353R, R356K, G359S, T377I, K390R, A400T, E404D, V435A, N447S, L452I, V466I, S468T, D471E, H483Q, L491S, A502T, S519N, A534S, A554S S134I