Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Perez-Alvarez (2001)
Title HIV-1 subtype G and BG recombinant viruses in Spanish natives: Evidence of characteristic mutations in reverse transcriptase and protease.
Citation AIDS
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 16
NumPts 16
Subtype G, B

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
MT-X254 MT-X254 None None   V35T, K43R, V60I, A98S, T165I, D177E, Q207A  
MT-X279 MT-X279 None None L74V  V35T, K43R, V60I, A98S, D123S, I135T, K173I, Q174K, D177E, T200A, Q207K, R211S K73N 
MT-X397 MT-X397 3TC, D4T, AZT NVP M184V K103N E28K, V35T, E36D, K43R, V60I, A98S, K122E, D123S, I135T, S162A, K173R, Q174K, D177E, T200A, Q207K, R211S  
MT-X415 MT-X415.3 None None   T39A, R83K, D123E, I135T, K166R, D177E, I202V, R211K, F214L, Q242H  
MT-X421 MT-X421 None None   V21G, V35T, E36D, K43R, V60I, A98S, K122E, D123S, I135T, T165I, K173R, Q174K, D177E, T200A, Q207K, R211S  
MT-X461 MT-X461 None None   V35T, K43R, K49R, V60I, K64R, A98S, K122E, D123S, K173I, Q174K, D177E, Q207A  
MT-X475 MT-X475 None None   V35T, K43R, V60I, A98S, K122E, D123S, I135T, K173I, Q174K, D177E, T200A, Q207K, R211S  
MT-X477 MT-X477 None None   V35T, K43R, V60I, A98S, K122E, D123N, K173I, Q174K, D177E, T200A, Q207K, R211S  
X254 X254 Unknown Unknown   V35T, K43R, V60I, A98S, D177E, Q207A, R211RK, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, I329L, R356K, A376S, K390R, A400T, E404D, K431T, V435A, F440Y, R461K, R463K, V466I, V467I, S468T, D471E, T477A, H483Q, L484I, L491S, K512R, S519N, A534S, A554N  
X397 X397 Unknown Unknown M184V K103N, N348I V35T, E36D, K43R, V60I, A98S, K122E, D123S, I135T, S162A, K173R, Q174K, D177E, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D320E, D324E, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, A371V, Q394R, A400V, E413D, Q428R, K431T, V435A, F440Y, R461K, R463K, V466I, V467I, S468T, D471E, T477A, H483Q, L484I, L491S, K512R, L517V, S519N, A534S, A554S  
X421 X421 Unknown Unknown   V35T, E36D, K43R, V60I, A98S, K122E, D123S, I135T, K173R, Q174K, D177E, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D320E, D324E, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, A371V, Q394R, A400V, E413D, Q428R, K431T, V435A, F440Y, R461K, R463K, V466I, V467I, S468T, D471E, T477A, H483Q, L484I, L491S, K512R, L517V, S519N, A534S, A554N  
X475 X475 Unknown Unknown   V35T, K43R, V60I, A98S, K122E, D123S, I135T, K173I, Q174K, D177E, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D320E, D324E, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, A371V, Q394R, A400V, E413D, K431T, V435A, F440Y, R461K, R463K, V466I, V467I, S468T, D471E, T477A, H483Q, L484I, L491S, K512R, L517V, S519N, A534S, A554S  
X477 X477 Unknown Unknown   V35T, K43R, V60I, A98S, K122E, D123N, K173I, Q174K, D177E, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D324E, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, A371V, Q394R, A400V, E413D, K431T, V435A, F440Y, R461K, R463K, V467I, S468T, D471E, T477A, H483Q, L484I, L491S, K512R, L517V, S519N, A534S, A554S  
X558 X558 None None   V35T, V60I, A98S, K122E, D123S, I135T, K173I, Q174K, D177E, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D320E, D324E, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, A371V, V381I, Q394R, A400V, E413D, Q428R, K431T, V435A, F440Y, R461K, R463K, V466I, V467I, S468T, D471E, T477A, Q480K, I482V, H483Q, L491S, K512R, S519N, A534S, A554S  
X605 X605 None None   V35T, K43R, V60I, A98S, K122E, D123S, I135IT, K173T, Q174K, D177E, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D320E, D324E, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, A371V, Q394R, A400V, E413D, Q428R, K431T, V435A, F440Y, R461K, R463K, V466I, V467I, S468T, D471E, T477A, H483Q, L484I, L491S, K512R, L517V, S519N, A534S, A554S  
X623 X623 AZT, D4T, DDI NVP   V35T, E36D, K43R, V60I, A98S, K122E, D123N, I135T, K173I, Q174K, D177E, T200A, I202V, Q207G, R211S, V245Q, E248N, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D320E, D324E, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, V365I, E370D, A371L, Q394R, A400V, E413D, Q428R, K431T, V435A, F440Y, R461K, R463K, V466I, V467I, S468T, D471E, T477A, H483Q, L484I, L491S, K512R, S519N, A534S, A554S  

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