Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Colonno (2004)
Title Identification of I50L as the signature atazanavir (ATV)-resistance mutation in treatment-naive HIV-1-infected patients receiving ATV-containing regimens.
Citation J Infect Dis
SelectedGene PR
SelectedSpecies HIV1
SelectedGroup M
SelectedType Lab
NumIsolates 12
Lab Parent Strain NL43, RF, Bru

 

Lab PR Isolates : Susceptibility Data


IsolatePIMajorDRMsPIMinorDRMsMethodDrugFold Res.
50L,71V-12 I50L  PhenoSense ATV 6.0 
     PhenoSense FPV 0.3 
     PhenoSense IDV 0.1 
     PhenoSense NFV 0.2 
     PhenoSense RTV 0.2 
50L-10 I50L  PhenoSense ATV 3.0 
     PhenoSense FPV 0.3 
     PhenoSense IDV 0.1 
     PhenoSense NFV 0.1 
     PhenoSense RTV 0.3 
71V-11   PhenoSense ATV 0.9 
    PhenoSense FPV 0.6 
    PhenoSense IDV 1.2 
    PhenoSense NFV 1.4 
    PhenoSense RTV 2.0 
  PhenoSense ATV 1.0 
    PhenoSense FPV 1.0 
    PhenoSense IDV 1.0 
    PhenoSense NFV 1.0 
    PhenoSense RTV 1.0 
A71V-7   PhenoSense ATV 2.0 
    PhenoSense FPV 0.3 
    PhenoSense IDV 1.0 
    PhenoSense NFV 1.3 
    PhenoSense RTV 0.7 
A71V-8 I50L  PhenoSense ATV 6.0 
     PhenoSense FPV 0.2 
     PhenoSense IDV 0.3 
     PhenoSense NFV 0.3 
     PhenoSense RTV 0.2 
Bru-1   PhenoSense ATV 1.0 
    PhenoSense FPV 1.0 
    PhenoSense IDV 1.0 
    PhenoSense NFV 1.0 
    PhenoSense RTV 1.0 
Bru-A71V-3   PhenoSense ATV 2.4 
    PhenoSense FPV 0.7 
    PhenoSense IDV 0.6 
    PhenoSense NFV 1.1 
    PhenoSense RTV 0.5 
Bru-I50L-2 I50L  PhenoSense ATV 5.4 
     PhenoSense FPV 0.2 
     PhenoSense IDV 0.1 
     PhenoSense NFV 0.2 
     PhenoSense RTV 0.1 
BruA71V-4 I50L  PhenoSense ATV 10 
     PhenoSense FPV 0.2 
     PhenoSense IDV 0.3 
     PhenoSense NFV 0.3 
     PhenoSense RTV 0.2 
I50L-6 I50L  PhenoSense ATV 2.0 
     PhenoSense FPV 0.1 
     PhenoSense IDV 0.1 
     PhenoSense NFV 0.1 
     PhenoSense RTV 0.1 
NL43-5   PhenoSense ATV 1.0 
    PhenoSense FPV 1.0 
    PhenoSense IDV 1.0 
    PhenoSense NFV 1.0 
    PhenoSense RTV 1.0