Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Rodenburg (2001)
Title Near full-length clones and reference sequences for subtype C isolates of HIV type 1 from three different continents.
Citation ARHR
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 13
NumPts 13
Subtype C, CRF07_BC, CRF08_BC

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
97CN001 97CN001 Unknown Unknown   V35T, E36A, T39D, S48T, V60I, V118I, D121Y, K122E, I135R, V245Q, Y271H, A272P, K277R, T286A, E291D, V292I, I293V, I326V, G335E, R356K, G359T, T377M, K390R, A400T, E404D, E432D, A437V, L452I, Q464K, V466I, D471E, H483C, L484I, L491S, S519N, K530R, A534S, A554S  
98BR004 98BR004 Unknown Unknown D67N, K70R  V35T, T39D, K43R, S48T, K122E, D123G, K173A, D177E, T200A, E203K, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, G335D, R356K, G359T, K366R, T377L, V381I, K390R, E404D, I411T, V435A, L452M, V458I, V466I, D471E, H483Q, L491S, S519N, K530R, A534S, A554K  
CR_94IN476 CR_94IN476 Unknown Unknown K65R  V35T, T39K, S48T, K122E, D123G, R125G, K173A, Q174R, D177K, Q197H, T200A, Q207A, R211K, V245K, A272P, K277R, T286A, E291D, V292I, I293V, Q334H, G335D, R356K, G359T, T377I, G384X, K390R, A400T, E404D, E413D, L452V, V466I, D471E, H483Q, L491T, S519N, K527N, K530R, A534S, K550R, A554S  
CR_96ZM651 CR_96ZM651 Unknown Unknown   V35T, E36A, T39E, S48T, K122E, D123S, I135T, K173A, T200A, Q207E, R211K, V245Q, P247A, K277R, T286A, E291D, V292I, I293V, R307K, Q334H, G335D, R356K, G359T, T377L, T386I, K390R, A400T, E404D, P421L, V458I, V466I, S468T, D471E, H483Y, L491S, Q509H, S519N, K530R, A534S, A554K  
CR_96ZM751 CR_96ZM751 Unknown Unknown   K20R, V35T, E36A, T39E, S48T, K122E, D123G, A158S, T165I, K173T, D177E, T200A, Q207E, V245K, D250E, A267X, K277R, T286A, E291D, V292I, I293V, N306S, Q334H, G335D, I341V, R356K, G359T, T377M, T386I, K390R, A400T, E404D, V435A, F440Y, L452I, V466I, S468T, D471E, H483Q, L491S, S519N, K530R, A534S, A554S  
CR_97ZA012 CR_97ZA012 Unknown Unknown   V35T, T39E, S48T, K122E, D123S, K173A, Q174K, D177E, T200A, E204D, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, E300K, I326V, Q334D, G335D, R356K, G359T, T377L, K390R, E399D, A400I, E404D, V435A, G436E, E449D, L452K, V466I, T470N, D471E, T477A, H483Q, S519N, E523G, K530R, V531I, A534S, A554S  
CR_98CN006 CR_98CN006 Unknown Unknown M184V  V35T, E36A, T39D, S48T, E53D, V60I, I135V, S162C, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, V317A, D324E, K331R, G335D, R356K, G359T, T377M, T386I, K390R, A400T, W401R, E404D, E432D, V435A, L452I, Q464K, V466I, D471E, H483Y, L484I, L491S, S519N, K530R, V531I, A534S, A554S  
CR_98CN009 CR_98CN009 Unknown Unknown   V35T, E36A, T39D, S48T, V60I, K102R, D121Y, K122E, I135T, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, V317I, G335D, R356K, G359T, T377M, K390R, A400I, E404D, E432D, A437V, L452I, Q464K, D471E, Q480H, H483C, L484I, L491S, S519N, K530R, A534S, A554S  
CR_98IN012 CR_98IN012 Unknown Unknown   V35T, E36A, T39D, S48T, V60I, K122E, D123S, K126R, I135R, K173A, D177E, T200A, Q207E, V245Q, D250E, A272P, K277R, K281R, T286A, E291D, V292I, I293V, Q334H, G335D, R356K, G359T, Q367R, T377L, T386I, F389L, K390R, A400T, E404D, V435I, A437V, L452I, V466I, D471E, H483Y, L491S, E516G, S519N, K530R, A534S, A554S, K558R  
CR_98IN022 CR_98IN022 Unknown Unknown   V35T, T39E, S48T, V60I, D121Y, K122E, A158S, S162A, K173T, D177E, T200A, Q207E, R211K, V245Q, A272P, K277R, E291D, I293V, D324E, Q334E, G335D, R356K, G359T, T377M, K390R, A400I, E404D, E432D, V435A, A437V, V466I, D471E, Q480H, H483Y, L491S, S519N, K527N, K530R, A534S, A554S  
CR_98IS002 CR_98IS002 Unknown Unknown   E6K, V35M, T39E, E40G, A98S, K122E, D123S, A158S, K173A, D177E, Q197K, T200A, E203D, Q207E, R211K, V245Q, A272P, K277R, E291D, V292I, I293V, A327V, Q334H, G335D, R356K, G359T, T377M, K390R, E404D, V435A, V466I, D471E, H483Q, L491S, L517I, S519N, K530R, A534S, A554S V111M 
CR_98TZ013 CR_98TZ013 Unknown Unknown   V35T, E36A, T39E, S48T, K122E, D123G, I135T, K173I, D177G, T200A, I202V, Q207E, R211K, V245Q, Y271H, A272S, V276I, K277R, T286A, E291D, V292I, I293V, E297K, A304E, G335D, R356K, G359S, V372I, T377M, K390R, A400T, E404D, V435A, F440Y, T450S, L452I, V458I, V466I, V467I, S468T, T470A, D471E, T477A, H483Q, L491S, E492K, V496A, K527G, K530R, A534S, A554S  
CR_98TZ017 CR_98TZ017 Unknown Unknown   K20R, V35T, E36A, T39E, S48T, I135T, T165I, K173T, D177E, T200A, Q207E, F214L, V245Q, A272P, T286A, E291D, V292I, I293V, D324E, Q334H, G335D, R356K, G359T, T377Q, I380V, K390R, A400T, T403A, E404D, E413D, V435A, A437V, K451R, L452I, V466I, S468T, D471E, T477S, H483Q, L491S, V493I, S519N, A534T, A554S Y127H, L295P