Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Bacheler (2001)
Title Genotypic correlates of phenotypic resistance to efavirenz in virus isolates from patients failing nonnucleoside reverse transcriptase inhibitor therapy.
Citation J Virol
SelectedGene PR
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 66
NumPts 34
Subtype B

 

Clinical PR Isolates


SubjectIsolatePIsWksPIMajorPIMinorCommonUnusual
DMP003-01 03-01000 None    L10I, E35D, M36I, I62V, L63P, V77I, I93L  
  03-01126 IDV 18   E35D, N37NST, L63P, V77VI  
DMP003-03 03-03000A None    L10V, K14KR, E35D, N37S, L63P, V77I, I93L  
  03-03134 IDV 19   L10V, K14R, E35D, N37S, L63P, V77I, I93L  
  03-03273 IDV 39   L10V, K14R, E35D, N37S, L63P, V77I, I93L  
DMP003-04 03-04186 IDV 27   L63S, I72V  
DMP003-07 03-07000 None    R41K, I93L  
  03-07502 IDV 72   R41K, I93L  
DMP003-20 03-20000 None    R57K, L63P, V77I, I93L  
  03-20206 IDV 29   R57K, L63P, I93L  
DMP003-21 03-21000 None    Q61DE, L63S  
  03-21503 IDV 72 M46L, V82A L24I L10I, I15V, L63T, I72V  
DMP003-24 03-24328 IDV 47   I93X  
DMP003-26 03-26000 None    I15IV, E35D, N37D  
  03-26014 IDV   I15IV, E35D, N37DE, L63LP  
  03-26125 IDV 18 V32I, V82A  E35D, N37D, L63P, A71V  
DMP003-28 03-28000 None    R41K, D60E, L63P, V77I, I93L  
  03-28321A IDV 46 I54V, V82A  L10I, R41K, D60E, L63P, V77I, I93L  
  03-28419 IDV 60   R41K, D60E, L63P, V77I, I93L  
DMP003-32 03-32000 None    I13V, K14KR, E35ED, N37S, R41K, L63P, I72V  
  03-32490 IDV 70 V82VA  I13V, K14R, E35D, N37S, R41K, I62IV, L63P, I72V, I93IL  
DMP003-44 03-44000B None    L63S, I64M, I72V  
  03-44259B IDV 37   L63S, I64M, E65D  
DMP003-47 03-47000 None    I13IV, L63LP  
  03-47497 IDV 71 V32VI, M46MI, V82VA, L90M G73GS L10I, I13V, L63P, A71IV, I72IL  
DMP003-50 03-50139 IDV 20 L76LV  L10I, I13V, M36I, D60E, Q61E, I62MV, L63P, I64M, A71V, I72T, I93L  
  03-50182 IDV 26 L76V  L10I, I13V, T31P, M36I, D60E, Q61E, I62V, L63P, I64M, A71V, I72T, I93L  
DMP003-55 03-55000 None    I13V, N37T, L63P, V77I  
  03-55126 IDV 18   I13V, N37T, L63P, V77I  
  03-55504 IDV 72   I13V, N37T, L63P, V77I  
DMP003-57 03-57000 None    K20R, N37D, L63S, A71V, I93L  
DMP003-63 03-63000 None    E35D, N37S, L63P  
DMP003-69 03-69000A None    E35D, R57K, L63P, K70R  
  03-69183C IDV 26   L10LR, E35D, R57K, L63P, K70R  
DMP003-70 03-70290B None    R41K, L63P, I93L  
  03-70290A IDV 41 I54V, V82A L33LF L10I, R41K, L63P, I93L  
DMP003-72 03-72183 IDV 26 I54V, V82A  L10I, R41K, L63P, I93L  
DMP003-73 03-73000 IDV 41 L90M  I62V, L63P, V77I, I93L  
DMP003-77 03-77000 None    R41K, K43R, I62V, L63P, V77IM, I93L  
DMP003-89 03-89000 IDV   L63P, K70KT  
  03-89503 IDV 72   T12S, I62V, L63T, V77I, I93L  
DMP003-94 03-94242B None    E35D, M36I, I62V, L63P, I72V, I93L  
  03-94000B IDV 35 V82A  E35D, M36I, I62V, L63P, I72V, I93L  
DMP003-99 03-99114 None    K14KR, L63P, K70Q  
  03-99000B IDV 16   K14R, I62V, L63H, K70Q  
DMP004-100 04-100000B None    L63A, V77I  
  04-100139B None    L63A  
DMP004-107 04-107230A None    I64V D25DA 
  04-107230B None    I64V  
DMP004-121 04-121000A None    L63P, V77I, I93L  
  04-121167 None    L63P, C67CW, V77I, I93L  
  04-121251 None    L63P, V77I, Q92R, I93L  
DMP004-126 04-126112 None    I13V, L63P  
DMP004-132 04-132000 None    L10I, T12I, I13V, G16E, M36I, I62V, L63A  
  04-132162 None    L10I, T12IK, I13V, G16E, M36I, I62V, L63A  
  04-132041 None    L10I, T12I, I13V, G16E, M36I, I62V, L63A  
DMP004-135 04-135000 None    R41K, I64V, K70R  
  04-135055 None    R41K, I64V, K70R  
DMP004-141 04-141000C None    T12S, I15V, L63P  
  04-141041 None    T12TS, K14KR, I15IV, L63P  
  04-141116B None    T12S, I15V, K43R, L63P  
DMP004-143 04-143000B None    E35D, L63P, I93L  
  04-143113 None    T31P, E35D, N37H, R41K, L63P, I93L R57RS 
DMP004-146 04-146000 None    R41RK, L63P, I64IV, K70R  
  04-146043 None    R41RK, L63P, I64IV, K70KR  
DMP004-147 04-147295 None    I15IV, E35D, N37S, L63C