Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Maguire (2002)
Title Emergence of resistance to protease inhibitor amprenavir in human immunodeficiency virus type 1-infected patients: Selection of four alternative viral protease genotypes and influence of viral susceptibility to coadministered reverse transcriptase nucleoside inhibitors.
Citation AAC
SelectedGene PR
SelectedSpecies HIV1
SelectedGroup M
SelectedType Lab
NumIsolates 28
Lab Parent Strain HXB2

 

Lab PR Isolates : Susceptibility Data


IsolatePIMajorDRMsPIMinorDRMsMethodDrugFold Res.
MM-L1 I54V, V82A  Antivirogram FPV 0.5 
MM-L10   Antivirogram FPV 1.4 
MM-L11 I84V  Antivirogram FPV 1.7 
MM-L12 I47V  Antivirogram FPV 1.9 
MM-L13   Antivirogram FPV 1.9 
MM-L14 I47V  Antivirogram FPV 2.2 
MM-L15 I54L L33F Antivirogram FPV 2.4 
MM-L16 I84V  Antivirogram FPV 2.4 
MM-L17 M46L, I50V  Antivirogram FPV 2.5 
MM-L18 M46L  Antivirogram FPV 2.6 
MM-L19 V32I  Antivirogram FPV 2.8 
MM-L2 I54V  Antivirogram FPV 0.7 
MM-L20 I54L  Antivirogram FPV 3.4 
MM-L21 I50V  Antivirogram FPV 3.5 
MM-L22 I54L L33F Antivirogram FPV 4.4 
MM-L23 I50V L33F Antivirogram FPV 4.4 
MM-L24 V32I, I47V  Antivirogram FPV 4.7 
MM-L25 I54M  Antivirogram FPV 5.4 
MM-L26 V32I, I47V  Antivirogram FPV 5.8 
MM-L27 I54M L33F Antivirogram FPV 6.5 
MM-L28 M46I, I50V  Antivirogram FPV 12 
MM-L3   Antivirogram FPV 0.8 
MM-L4 I54V L33F Antivirogram FPV 0.8 
MM-L5  L33F Antivirogram FPV 0.9 
MM-L6 I54V L33F Antivirogram FPV 0.9 
MM-L7 L90M  Antivirogram FPV 1.1 
MM-L8 V82A  Antivirogram FPV 1.1 
MM-L9  L33F Antivirogram FPV 1.4