Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Perez (2001)
Title Human immunodeficiency virus type 1 protease genotype predicts immune and viral responses to combination therapy with protease inhibitors (PIs) in PI-naive patients.
Citation J Infect Dis
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 19
NumPts 19
Subtype B

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
EP-1329 EP-1329 NRTI None T215Y  V60I, I135V, I142F, A158AS, S162A, Q207E, R211K, V245K W239L, T240E 
EP-1470 EP-1470 NRTI None K70R, K219KE  R211K, V245M  
EP-1738 EP-1738 NRTI None D67N, T69D, K70R, T215F, K219Q  K43Q, V60I, K103R, K122E, Q207E, R211K, L228H, V245K  
EP-1838 EP-1838 NRTI None D67H, L210W, T215Y  K64R, L100*, D123E, Y144F, K173N, Q174K, D177E, R211K, V245M  
EP-1875 EP-1875 NRTI None   V60I, I135T, K173X, T200A, Q207E, L210F, P243S Y144G 
EP-1877 EP-1877 NRTI None D67N, K70R, M184V, K219Q  E53D, K64H, T69N, V90I, K122E, F214L, V245E  
EP-1916 EP-1916 NRTI None M41L, L210W, T215Y  K43N, I63*, K64R, D121Y, K122E, F171L, K173R, D177E, I178L, H208Y, R211K R172E 
EP-1934 EP-1934 NRTI None M41L, D67N, T69D, M184V, L210W, T215Y V106I V118I, S162C, E169D, K173N, Q174K, I178L, Q207E, H208F, R211K  
EP-1937 EP-1937 NRTI None M41L, L210W, T215Y  V60I, I63*, R83K, D123E, Y144F, K173N, Q174K, I178L, R211K P59S 
EP-1989 EP-1989 NRTI None   D123E, I135IM, Y144F, K173N, Q174K, Q207E, L210*, R211K  
EP-2000 EP-2000 NRTI None A62V, L210W, T215Y  I63*, K64R, T69S, D121Y, K122E, A158S, S162D, F171L, K173N, Q174K, I178L, Q207E, R211K R172E 
EP-2041 EP-2041 NRTI None  V106VI K122E, D123S, F214L  
EP-2141 EP-2141 NRTI None M41L, D67N, T69D, L210W, T215Y V106I K43E, I63*, K64R, V118I, S162D, R211K, V245VM  
EP-2154 EP-2154 NRTI None M41L, D67N, L74I, L210W, T215Y  I63*, K64R, R83K, K104E, V118I, Q174H, I178M, G196E, Q207E, R211K, V245E  
EP-2208 EP-2208 NRTI None   K122E  
EP-2272 EP-2272 NRTI None M41L, D67DN, K70R, T215Y  D123E, I135T, I142V, S162A, D177E, I178V, G196E, T200A, Q207E A98E 
EP-2546 EP-2546 NRTI None M184V  A158S, E169D, R211K, V245E  
EP-2550 EP-2550 NRTI None M41L, M184V  D177E, T200A, R211K  
EP-2612 EP-2612 NRTI None D67N, K70R, M184V  K122E, V179I, V245E  

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