Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Brindeiro (1999)
Title Sequence diversity of the reverse transcriptase of human immunodeficiency virus type 1 from untreated Brazilian individuals.
Citation AAC
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 18
NumPts 18
Subtype B, F, D, C, B + C

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
Brp004 Brp004 None None D67N, K70R, T215F, K219Q E138A E36K, K102R, I135T, T200A, R211K P140Q, F160S, S191P, T216S, H221R 
Brp011 Brp011 None None   K49R, D123E, I135T, E169D  
Brp019 Brp019 None None   E36K, V60L, D121Y, K122E, D123N, I135T  
Brp026 Brp026 None None  E138A D76N, D113N, D121N, D123E, I135T, I202V K46T, I167T, H221P 
Brp030 Brp030 None None   K46Q, S48T, D76N, S117SP, D121N, I135T, R143K, Q145H, F214I K126N, S134I, T216A, H221R 
Brp034 Brp034 None None   T39M, D76N, K122KE, S162C, E169D, K173T, Q174K, Q207E, R211K K46T, S134V, F160S, I167T, N175K, I180NS 
Brp035 Brp035 None None   T39L, D76N, I135T, S162Y, K173T, Q174K, D177DE, Q207G, R211K K46T, Q182QP 
Brp044 Brp044 None None   E36K, I135T, Q145H, R211RG  
Brp063 Brp063 None None M41L  E36K, K43R, V75VL, D76N, T200E, Q207E, R211K, F214L G213R 
Brp066 Brp066 None None   E36K, D76N, V118I, D121N, D123E, I135T, R211K, F214L K126N, T216S, H221R 
Brp069 Brp069 None None M41L  E36K, N57Y, D76DN, K122A, I135V, S162C, D177E, T200A  
Brp072 Brp072 None None   E40D, K49R, I50V, V60I, D76N, R172K, Q174L, D177E, I178V, R199K, Q207E H208R, T216A, H221R 
Brp089 Brp089 None None   T69TA, D121N, D123N, I135T, Y144F, V189I, Q207R, R211K T216S 
Brp093 Brp093 None None   T39A, D76N, K102Q, S162C, T216P H221P 
Brp127 Brp127 None None   K49R, D76N, D121N, D123E, S162C, E169D, K173A, Q174K, T200A, Q207A, R211K K46T 
Brp130 Brp130 None None   E36K, D76N, D121H, K122E, I135T, I202V, F214L, H221L V90F 
Brp134 Brp134 None None K70N  T39D, K43R, S48T, D123N, I135T, E169K, D177E, R211K, F214L V90F, S134I 
Brp136 Brp136 None None K70N  T39E, K46Q, S48T, D76N, D86N, V106L, V111L, D121N, D123N, I135M, R143K, Y144F, A158S, S163I, E169K, K173A, D177E, T200A, Q207G, R211K, F214L A62S, V90F, T128P, S134I, V148L, H221R