Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Ziermann (2000)
Title A mutation in human immunodeficiency virus type 1 protease, N88S, that causes in vitro hypersensitivity to amprenavir.
Citation J Virol
SelectedGene PR
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 20
NumPts 20
Subtype B

 

Clinical PR Isolates


SubjectIsolatePIsWksPIMajorPIMinorCommonUnusual
RZ1 RZ1 Unknown  N88S K20T K14R, I15V, E35D, M36I, R41K, I62V, L63Q  
RZ10 RZ10 Unknown  M46I, N88S  L10I, E35D, N37S, L63P, A71T, V77I  
RZ11 RZ11 Unknown  N88NS  R41K, I62V, L63P, V77I, I93L  
RZ12 RZ12 Unknown  M46MI, V82AT L10LF M36ML, L63S, I64V, I72T, V77I  
RZ13 RZ13 Unknown  I54V, V82A  K20R, M36I, R41K, I64V, H69Y  
RZ14 RZ14 Unknown  N88S, L90M K20T I15V, R41K, K45R, R57K, L63P, A71V, I72M  
RZ15 RZ15 Unknown  N88NDS  I13V, I15V, K20KM, E35D, N37D, L63P, A71AT  
RZ16 RZ16 Unknown  I54IV, V82VA  E35D, M36I, I62V, L63P, H69Q, A71AV  
RZ17 RZ17 Unknown  N88NS  K14R, I15V, M36MI, N37S, R41K, I62V, L63Q, V77VI  
RZ18 RZ18 Unknown  D30N  I13V, E35D, M36I, N37D, R57K, I62V, L63H, I64V, A71V, I93L  
RZ19 RZ19 Unknown  D30DN  E35D, M36V, N37S, I64V  
RZ2 RZ2 Unknown  M46L, N88S  I13V, E35D, L63P, I64V, I72V  
RZ20 RZ20 Unknown  D30N N88D T12A, I13V, L33I, M36MI, R57K, L63P, I93L  
RZ3 RZ3 Unknown  N88S  I62V, L63P, V77I  
RZ4 RZ4 Unknown  N88S  I13V, E35D, M36I, I62V, L63P, A71AT  
RZ5 RZ5 Unknown  M46I, N88S  I13V, K20M, M36V, N37A, I62V, L63P, I93L  
RZ6 RZ6 Unknown  M46I, N88S  L63P, V77I, I93L  
RZ7 RZ7 Unknown  M46I, N88S  I13V, K14R, N37D, L63P, I93L  
RZ8 RZ8 Unknown  M46I, N88S  I13V, R41K, L63P, V77I, I93L  
RZ9 RZ9 Unknown  I54V, L90LM N83D L10I, I13V, K20KR, M36I, I62V, L63H, I64V, I72V