Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Becker-Pergola (2000)
Title Analysis of HIV type 1 protease and reverse transcriptase in antiretroviral drug naive Ugandan adults.
Citation ARHR
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 27
NumPts 27
Subtype A, D

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
108.448 BPG108.448 None None   V35T, I50IV, V60I, K122E, D123S, K173AS, Q174K, D177E, V179I, T200A, Q207A, R211S, V245Q, E248N, T286A, A288AS, V292VI, I293V, E312D  
129.733 BPG129-733 None None   E6N, V35T, K43KR, S48SA, V60I, K122E, D123S, I135T, K173S, Q174K, D177E, V179I, I202V, Q207D, R211S, V245E, D250E, S251SN, T286A, E291D, V292I, I293V, P294T, E312D  
134.463 BPG134-463 None None   E6EK, V35T, E36D, K49KR, V60I, K122E, T165TA, E169D, D177E, I178M, T200I, Q207G, R211K, V245K, D250E, A272P, K277R, L282C, L283I, T286A, V292I, I293V  
135.544 BPG135-544 None None   K20R, V21I, V35T, T39R, V60I, K102Q, D123NS, K173S, D177E, V179I, T200A, I202V, Q207A, R211S, F214FL, V245Q, E248D, T286A, E291D, V292I, I293V, P294T  
140.223 BPG140-223 None None   K11T, K20R, V21I, V35T, T39R, D123N, K173S, D177G, V179I, I202V, Q207A, R211S, V245Q, E248D, T286A, E291D, V292I, I293V, E312D  
151.940 BPG151-940 None None   P4H, V35T, E40D, K49R, V60I, D121Y, K122E, D123E, I159V, D177E, I178M, T200I, Q207G, R211K, V245K, D250E, A272P, L282C, L283I, R284K, I293V, L310Q  
161.287 BPG161-287 None None   K11T, V21I, V35T, T39K, K122E, D123S, K173S, D177G, V179I, I202V, Q207A, R211K, V245Q, E248D, T286A, E291D, V292I, I293V  
171.005 BPG171-005 None None   E6D, V35T, E40D, K43R, V118I, K122E, D123N, I135T, S162G, K173S, Q174K, D177E, V179I, Q207A, R211S, F214L, P243S, V245E, A272P, K281R, E291D, I293V, P294T, E312D  
184.574 BPG184-574 None None   K20R, V35T, V60I, K122E, D123S, I135T, I142V, I159V, K173L, Q174K, D177E, I178V, V179I, G196E, Q207A, R211S, D250E, A272P, V276I, T286A, E291D, V292I, I293V, P294T, E312D  
190.574 BPG190-574 None None   V35T, E40D, V60I, K122E, D123S, I135T, A158S, T165I, K173LS, Q174K, D177E, V179I, T200A, Q207A, R211S, V245E, D250E, E291D, I293V, E297K, E312D  
194.793 BPG194-793 None None   E6N, V35T, V60I, K122E, D123S, I135T, T139M, S162Y, K173L, Q174K, D177E, V179I, Q207E, R211S, V245Q, D250E, T286A, E291D, V292I, I293V, L295M, E312D  
204.987 BPG204-987 None None   E6D, V35T, V60I, K122E, D123S, I135T, Y146S, K173L, Q174K, D177E, I178M, V179I, Q207A, R211S, V245T, D250E, A272P, K277R, T286A, E291D, I293V, P294T, E312D  
225.706 BPG225-706 None None   E6DN, V35T, E40D, V60I, K122E, D123N, I135T, K173A, Q174K, D177E, I178IL, V179I, I202V, Q207K, R211S, F214L, V245E, D250E, V261I, T286A, E291D, V292VI, I293V, P294T, E312D  
225.710 BPG225-710 None None   E6ED, V35T, T39K, K122E, D123S, I135T, I178M, T200I, Q207E, R211K, V245K, D250E, K277R, L282C, T286A, I293V, E300EQ  
225.745 BPG225.745 None None   K11Q, E29D, V35T, T39A, E40D, K49R, K122E, D123S, I135T, I142V, K173S, D177E, V179I, T200A, Q207A, R211S, V245Q, K281R, L283I, E291ED, I293V, P294T, E312D  
230.298 BPG230-298 None None   T27TP, V35T, S48SL, V60I, D121DY, K122E, D123G, D177E, I178M, T200I, Q207E, R211K, V245K, D250E, A272P, K275R, K277R, Q278H, L282C, T286A  
230.580 BPG230-580 None None   E6D, V8I, V35T, V60I, K122E, D123S, I135T, K173L, Q174K, D177E, I178V, Q207A, R211S, K277R, T286A, E291D, V292VI, I293V, P294T, E312D  
326.570 BPG326-570 None None   V35T, T39I, V60I, K122E, D123EG, I135T, D177E, Q207E, V245E, D250E, A272P, T286A, I293V  
326.636 BPG326-636 None None   E6N, V35T, T39A, V60I, K122E, D123S, I135T, K173S, Q174X, D177E, I178M, T200TA, Q207EG, V245K, D250E, E291D, V292I, I293V, P294T, E312D  
326.642 BPG326-642 None None   P4S, K11T, K20R, V21I, V35T, T39K, K122E, D123S, I135T, I142IV, K173S, D177E, I178V, I202V, Q207A, R211K, V245Q, E248N, K277R, T286A, E291D, V292I, I293V, P294T, E312D  
326.662 BPG326-662 None None   V35T, E36A, T39D, K49R, V60I, T165I, D177E, I178IMV, V179VI, Q207A, V245K, D250E, A272P, K277R, L282C, T286A, A288T, V292VI, I293V T216TA 
326.675 BPG326-675 None None   K11T, K20R, V21I, V35T, T39K, K122KE, D123S, K173A, D177E, V179I, I202V, Q207A, R211N, V245Q, E248N, T286A, E291D, V292I, I293V, P294T, E312N  
42.877 BPG42-877 None None   V35T, K43R, K49R, V60I, D121Y, K122E, D177E, Q207E, R211RK, V245I, D250E, A272S, K277S  
501.045 BPG501-045 None None   V35T, K49R, V60I, S68N, D121Y, K122E, R125K, G141E, K173T, D177E, I178IM, T200V, Q207G, R211K, E224ED, V245K, D250E, A272P, K277R, L282C, T286A, I293V  
503.083 BPG503-083 None None   T39TP, K49R, V60I, D121DH, K122KE, D177E, I178M, T200I, Q207E, R211K, V245K, D250E, A272P, K277R, L282C, T286A, I293V  
602.174 BPG602-174 None None   V35T, E40ED, V60I, K122E, D123E, I135T, D177E, T200S, Q207E, V245E, D250E, K277R, T286A, V292VI, I293V  
99.237 BPG99-237 None None   E6DN, V35T, V60I, K122E, D123N, I135T, K173L, Q174K, D177E, V179I, Q207A, R211S, V245K, E248D, D250E, A272P, K277R, T286A, E291D, V292I, I293V, P294T, E312D