Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Larder (1999)
Title A family of insertion mutations between codons 67 and 70 of human immunodeficiency virus type 1 reverse transcriptase confer multinucleoside analog resistance.
Citation AAC
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Lab
NumIsolates 5
Lab Parent Strain HXB2

 

Lab RT Isolates : Susceptibility Data


IsolateNRTIDRMsNNRTIDRMsMethodDrugFold Res.
210-215 L210W, T215Y  Antivirogram 3TC 4.0 
     Antivirogram ABC 2.0 
     Antivirogram AZT 10 
     Antivirogram D4T 1.0 
     Antivirogram DDC 1.0 
     Antivirogram DDI 1.0 
62-210-215 A62V, L210W, T215Y  Antivirogram 3TC 1.0 
     Antivirogram ABC 1.0 
     Antivirogram AZT 8.0 
     Antivirogram D4T 1.0 
     Antivirogram DDC 1.0 
     Antivirogram DDI 1.0 
62-69SSS-2 A62V, T69T_SS, L210W, T215Y  Antivirogram 3TC 15 
     Antivirogram ABC 5.0 
     Antivirogram AZT >2,500 
     Antivirogram D4T 5.0 
     Antivirogram DDC 3.0 
     Antivirogram DDI 2.0 
69SSS T69T_SS  Antivirogram 3TC 6.0 
     Antivirogram ABC 3.0 
     Antivirogram AZT 2.0 
     Antivirogram D4T 2.0 
     Antivirogram DDC 2.0 
     Antivirogram DDI 2.0 
69SSS,210 T69T_SS, L210W, T215Y  Antivirogram 3TC 20 
     Antivirogram ABC 5.0 
     Antivirogram AZT 220 
     Antivirogram D4T 5.0 
     Antivirogram DDC 4.0 
     Antivirogram DDI 2.0