Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Tisdale (1995)
Title Cross-resistance analysis of human immunodeficiency virus type 1 variants individually selected for resistance to five different protease inhibitors.
Citation AAC
SelectedGene PR
SelectedSpecies HIV1
SelectedGroup M
SelectedType Lab
NumIsolates 10
Lab Parent Strain HXB2

 

Lab PR Isolates : Susceptibility Data


IsolatePIMajorDRMsPIMinorDRMsMethodDrugFold Res.
H10-45-84 I84V L10F Cell protection FPV 6.0 
      Cell protection IDV 3.0 
      Cell protection SQV 3.0 
H46-71-82 V32I, M46L, V82A  Cell protection FPV 1.0 
     Cell protection IDV 6.0 
     Cell protection SQV 0.2 
H46I-50 M46I, I50V  Cell protection FPV 6.0 
     Cell protection IDV 0.5 
     Cell protection SQV 0.4 
H46L-50 M46L, I50V  Cell protection FPV 3.0 
     Cell protection IDV 0.3 
     Cell protection SQV 0.2 
H71-84-90 G48V, I84V, L90M  Cell protection FPV 2.0 
     Cell protection IDV 4.0 
     Cell protection SQV 40 
H8-46-48 M46I, G48V  Cell protection FPV 1.0 
     Cell protection IDV 1.0 
     Cell protection SQV 1.0 
HXB2   Cell protection FPV 1.0 
    Cell protection IDV 1.0 
    Cell protection SQV 1.0 
HXB2-10-84 I84V L10F Cell protection FPV 3.0 
      Cell protection IDV 1.0 
      Cell protection SQV 3.0 
HXB2-46-82 M46L, V82A  Cell protection FPV 1.0 
     Cell protection IDV 2.0 
     Cell protection SQV 0.2 
HXB2-48-90 G48V, L90M  Cell protection FPV 1.0 
     Cell protection IDV 2.0 
     Cell protection SQV 36