Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Kellam (1992)
Title Fifth mutation in human immunodeficiency virus type 1 reverse transcriptase contributes to the development of high-level resistance to zidovudine.
Citation PNAS
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Lab
NumIsolates 6
Lab Parent Strain HXB2

 

Lab RT Isolates : Susceptibility Data


IsolateNRTIDRMsNNRTIDRMsMethodDrugFold Res.
H67-70-21 M41L, D67N, K70R, T215Y  Plaque reduction AZT 180 
H70-215F- D67N, K70R, K219Q  Plaque reduction AZT 150 
H70-215Y- D67N, K70R, T215Y, K219Q  Plaque reduction AZT 120 
HXB-41-215 M41L, T215Y  Plaque reduction AZT 60 
HXB-M41L M41L  Plaque reduction AZT 4.0 
HXB-T215Y T215Y  Plaque reduction AZT 16