Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Young (1995)
Title L-743,726 (DMP-266): a novel, highly potent nonnucleoside inhibitor of the human immunodeficiency virus type 1 reverse transcriptase.
Citation AAC
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Lab
NumIsolates 13
Lab Parent Strain NL43, IIIB

 

Lab RT Isolates : Susceptibility Data


IsolateNRTIDRMsNNRTIDRMsMethodDrugFold Res.
100-101  L100I, K101E Cell protection EFV 500 
100-103  L100I, K103N Cell protection EFV 8,000 
101-103  K101E, K103N Cell protection EFV 500 
103-181  K103N, Y181C Cell protection EFV 130 
A98G  A98G Cell protection EFV 4.0 
K101E  K101E Cell protection EFV 8.0 
K103N  K103N Cell protection EFV 33 
L100I  L100I Cell protection EFV 33 
V106A  V106A Cell protection EFV 4.0 
V108I  V108I Cell protection EFV 1.0 
V179D  V179D Cell protection EFV 1.0 
Y181C  Y181C Cell protection EFV 2.0 
Y188L  Y188L Cell protection EFV 500