Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Craig (1998)
Title HIV protease genotype and viral sensitivity to HIV protease inhibitors following saquinavir therapy.
Citation AIDS
SelectedGene PR
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 38
NumPts 19
Subtype B

 

Clinical PR Isolates


SubjectIsolatePIsWksPIMajorPIMinorCommonUnusual
Craig-pt1 1B None    L63S, A71T  
  1W24 SQV 24  Q58E Q18R, M36I, L63T, A71T  
Craig-pt10 10B None      
  10W60 SQV 60 V82A  T74S  
Craig-pt11 11B None    I15V, R41K, L63I  
  11W29 SQV 29   K14R, I15V, R41K, L63I, V77I  
Craig-pt13 13B None    A71T, I93L  
  13W147 SQV 147   I13V, L63A, V82I  
Craig-pt14 14B None    I13V, L23X, I62V, L63H  
  14W40 SQV 40 L90M G73S L5I, L10X, I62V, L63H  
Craig-pt15 15B None    N37D, L63P  
  15W48 SQV 48 I84V, L90M N88D M36I, N37D, L63P, A71V  
Craig-pt16 16B None    L10I, L63C, I93L  
  16W44 SQV 44 L90M  L10I, T12A, K14R, D60E, L63C, I64V, A71V, I93L  
Craig-pt18 18B None    T12I, I13V, N37A, L63P  
  18W20 SQV 20 L90M  L5F, T12I, I13V, N37D, L63P, A71T, V77I  
Craig-pt19 19B None    M36I, L63P, H69Q  
  19W24 SQV 24 M46I  R41K, L63P, H69Q  
Craig-pt20 20B None    I13V, M36I, N37D, L63P, I64V  
  20W147 SQV 147 L90M  I13V, K20R, M36I, N37D, L63P, I64V  
Craig-Pt21 21B None    Q18L, V77I  
  21W48 SQV 48 I84V, L90M  Q18L, A71V, V77I  
Craig-Pt22 22B None    L10V, L63Q, I64V  
  22W48 SQV 48 M46I, G48V, L90M  L10V, M36I, D60E, L63Q, I64V, I72V  
Craig-pt23 23B None    I64V  
  23W40 SQV 40 I84V, L90M  L10Y, L63P, I64V  
Craig-pt25 25B None   L10F I62V, L63P  
  25W24 SQV 24 L90M  I62V, L63P, A71V  
Craig-pt26 26B None    E35D, N37E, I62V, L63P, T74A  
  26W72 SQV 72 L90M  E35D, N37E, I62V, L63P, I64V, A71T  
Craig-pt32 32B None    M36I, N37S, I62V, L63P  
  32W24 SQV 24 L90M G73S I13V, K20R, M36I, N37S, I62V, L63P  
Craig-pt34 34B None    N37S, R41K  
  34W24 SQV 24 G48V, V82A  L10T, N37S, R41K, D60N, L63P, T74S, V77I  
Craig-pt38 38B None    N37S, L63P, V77I  
  38W48 SQV 48 L90M G73S L10I, I15V, N37S, I62V, L63P, A71V, I72T, V77I  
Craig-pt40 40B None    I72V  
  40W24 SQV 24 G48V, V82A  I72V, T74S