Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Shafer (1997)
Title Sequence and drug susceptibility of subtype C reverse transcriptase from human immunodeficiency virus type 1 seroconverters in Zimbabwe.
Citation J Virol
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 12
NumPts 12
Subtype C

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
Z1226 Z1226 None None   V35K, E36A, T39E, S48T, K49R, V60I, V90I, I142M, S162T, K173A, D177G, G196E, T200A, Q207E  
Z1373 Z1373 None None   V35T, T39E, S48T, K122E, K173A, D177E, T200A, R211K, V245R  
Z1373s Z1373s None None   V35T, T39E, S48T, K122E, A158S, K173A, D177E, T200A, Q207G, R211RK, V245Q  
Z1614 Z1614 None None   V35T, E36A, T39E, S48T, K122E, D123N, K173T, D177E, T200A, Q207E, V245Q  
Z1624 Z1624 None None   V35T, E36A, T39E, S48T, K122E, D123G, S162A, K173A, D177E, T200A, Q207E, V245Q  
Z1782 Z1782 None None   T27S, V35T, E36A, T39E, S48T, V60I, K122E, D123G, K173T, T200A, Q207E, R211K, V245Q  
Z1875 Z1875 None None   V35T, E36A, T39E, S48T, V60I, K122E, D123G, I135T, S162A, K173A, D177E, T200A, Q207E, R211K  
Z2107 Z2107 None None   V35T, T39E, S48T, K122E, D123G, K166R, K173A, Q174E, T200A, Q207E, V245Q  
Z2288 Z2288 None None   V35T, E36A, T39E, S48T, K122E, D123G, K173A, D177E, T200A, Q207E, V245Q  
Z2396 Z2396 None None   V35T, E36A, T39E, S48T, K122E, D123G, A158S, S162A, K173T, D177E, T200A, Q207K, V245Q  
Z295 Z295 None None   V35T, T39E, S48T, E53D, K166R, K173T, Q174E, D177E, T200A, Q207E, R211K, V245K  
Z84 Z84 None None   V35K, T39E, S48T, V60I, T139A, K173T, D177E, I178M, G196E, T200A, Q207E