Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.


Author Mellors (1995)
Title Novel mutations in reverse transcriptase of human immunodeficiency virus type 1 reduce susceptibility to foscarnet in laboratory and clinical isolates.
Citation AAC
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Lab
NumIsolates 7
Lab Parent Strain Bru


Lab RT Isolates : Susceptibility Data

IsolateNRTIDRMsNNRTIDRMsMethodDrugFold Res.
161-208   Plaque reduction PFA 7.0 
    Plaque reduction PFA 8.0 
161L   Plaque reduction PFA 10 
    Plaque reduction PFA 5.0 
161L-208Y   Plaque reduction AZT 0.1 
    Plaque reduction D4T 0.6 
    Plaque reduction DDI 1.0 
    Plaque reduction NVP 0.1 
    Plaque reduction PFA >9.0 
208   Plaque reduction PFA 2.0 
    Plaque reduction PFA 2.0 
88S   Plaque reduction PFA 4.0 
    Plaque reduction PFA 3.0 
89G   Plaque reduction PFA 14 
    Plaque reduction PFA 12 
LAI   Plaque reduction AZT 1.0 
    Plaque reduction D4T 1.0 
    Plaque reduction DDI 1.0 
    Plaque reduction NVP 1.0 
    Plaque reduction PFA 1.0