Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Larder (1993)
Title Convergent combination therapy can select viable multidrug-resistant HIV-1 in vitro.
Citation Nature
SelectedGene RT
SelectedSpecies HIV1
SelectedType Lab
NumIsolates 6
Lab Parent Strain HXB2

 

Lab RT Isolates : Susceptibility Data


IsolateNRTIDRMsNNRTIDRMsMethodDrugFold Res.
41-106-215 M41L, T215Y V106A Plaque reduction AZT 110 
      Plaque reduction NVP 300 
41-215 M41L, T215Y  Plaque reduction 3TC 1.0 
     Plaque reduction AZT 65 
     Plaque reduction DDI 1.9 
     Plaque reduction NVP 1.0 
41-74-106- M41L, L74V, T215Y V106A Plaque reduction 3TC 1.0 
  M41L, L74V, M184V, T215Y   Plaque reduction 3TC 2,000 
  M41L, L74V, T215Y   Plaque reduction AZT 9.4 
  M41L, L74V, M184V, T215Y   Plaque reduction AZT 1.0 
  M41L, L74V, T215Y   Plaque reduction DDI 9.4 
  M41L, L74V, M184V, T215Y   Plaque reduction DDI 19 
  M41L, L74V, T215Y   Plaque reduction NVP 300 
  M41L, L74V, M184V, T215Y   Plaque reduction NVP 150 
41-74-181- M41L, L74V, T215Y Y181C Plaque reduction AZT 7.0 
      Plaque reduction DDI 4.5 
      Plaque reduction NVP 110 
41-74-215 M41L, L74V, T215Y  Plaque reduction AZT 33 
     Plaque reduction DDI 8.9 
     Plaque reduction NVP 1.0