Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Kelentse (2020)
Title Differences in human immunodeficiency virus-1C viral load and drug resistance mutation between plasma and cerebrospinal fluid in patients with human immunodeficiency virus-associated cryptococcal meningitis in Botswana.
Citation Medicine (Baltimore)
SelectedGene PR
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 52
NumPts 26
Subtype C

 

Clinical PR Isolates


SubjectIsolatePIsWksPIMajorPIMinorCommonUnusual
1057 1057PLASMA Unknown    I15V, G16E, N37C, R41K, D60E, I62V, L63T, I64V, H69K, V77I, I93L  
  1057CSF Unknown    I15V, G16E, N37T, R41K, D60E, I62V, L63T, G68E, H69K, V77I, I93L  
1121 1121CSF Unknown    T12S, I15V, L19I, K20KR, E35D, M36I, R41K, I62IV, L63V, H69K, T74S, V82I, L89M, I93L  
  1121PLASMA Unknown    T12S, I15V, L19I, E35D, M36I, R41K, R57RK, L63V, H69K, T74S, V82I, L89M, I93L  
1134 1134CSF Unknown    I15V, E35D, M36I, R41K, K45R, L63A, H69K, T74S, L89M, I93L  
  1134PLASMA Unknown    I15V, L19I, E35D, M36I, N37D, R41K, K45R, L63A, H69K, T74S, L89M, I93L  
1215 1215PLASMA Unknown    T12S, I15V, L19T, M36I, Q61E, L63P, H69K, V82I, L89M, I93L  
  1215CSF Unknown    T12S, I15V, L19T, M36I, Q61E, L63P, H69K, V82I, L89M, I93L  
1255 1255PLASMA Unknown    I15V, L19I, E35D, M36I, K45R, L63T, H69K, V82I, L89M, I93L  
  1255CSF Unknown    T4TS, I15V, L19I, E35D, M36I, K45KR, L63T, H69K, V82I, L89M, I93L L5LV, D30DE 
1259 1259PLASMA Unknown    T12S, I15V, L19I, E35D, M36I, N37D, R57K, I62IV, L63A, H69K, A71T, I93L  
  1259CSF Unknown    T12S, I15V, L19I, E35D, M36I, N37D, R57K, I62V, L63A, H69K, A71T, I93L  
1310 1310CSF Unknown    T12S, L19T, M36I, R41K, Q61N, L63P, H69K, L89M, I93L  
  1310PLASMA Unknown    T12S, L19T, M36I, R41K, Q61N, L63P, H69K, I85IV, L89M, Q92QL, I93LV V77VG, P81PA 
1326 1326PLASMA Unknown    I15V, R41K, L63T, H69K, V77I, I93L  
  1326CSF Unknown    I15V, R41K, L63T, H69K, V77I, I93L  
1352 1352CSF Unknown    T12S, I15V, L19I, M36I, R41K, L63P, H69K, I93L  
  1352PLASMA Unknown    L5LP, T12S, I15V, L19IT, M36I, R41K, L63P, H69K, I93L  
1362 1362PLASMA Unknown    T12S, I15V, L19I, M36I, N37D, R41K, L63P, H69K, L89M, I93L  
  1362CSF Unknown    T12S, I15V, L19I, M36I, N37D, R41K, L63P, H69K, L89M, I93L  
1374 1374PLASMA Unknown    T12S, I15V, L19V, M36I, R41K, L63P, H69K, I93L  
  1374CSF Unknown    T12S, I15V, L19V, M36I, R41K, L63P, H69K, I93L  
1383 1383CSF Unknown    T12S, I15V, L19I, M36I, R41K, L63P, H69K, I93L  
  1383PLASMA Unknown    T12S, I15V, L19I, M36I, R41K, L63P, H69K, I93L  
1452 1452CSF Unknown    T12S, I15V, L19I, K20R, E35D, M36I, N37D, R41K, D60E, Q61E, L63P, H69K, I72M, L89M, I93L  
  1452PLASMA Unknown    T12S, I15V, L19I, K20R, E35D, M36IL, N37D, R41K, D60E, Q61E, L63P, H69K, I72IM, V77I, L89M, I93L  
1500 1500PLASMA Unknown    T12S, I13V, I15V, G17D, L19V, K20R, M36I, N37K, R41K, Q61H, L63A, H69K, I72V, L89M, I93L  
  1500CSF Unknown    T12S, I13V, I15V, G17D, L19V, K20R, M36I, N37K, R41K, Q61H, L63A, H69K, V82I, L89M, I93L  
1528 1528CSF Unknown    T12S, I15IV, L19I, M36I, R41K, H69K, T74S, L89M, I93L  
  1528PLASMA Unknown    T12S, I15IV, L19I, M36I, R41K, H69K, T74S, L89M, I93L  
1724 1724CSF Unknown    T4TI, L5LF, T12E, I15V, L19I, E35D, M36I, R41K, R57K, Q61E, H69K, V77I, L89M, I93L  
  1724PLASMA Unknown    T12E, I15V, L19I, E35D, M36I, R41K, R57RK, Q61E, H69K, V77I, L89M, I93L  
1730 1730CSF Unknown    T12S, I15V, L19I, E35D, M36I, R41K, L63V, H69K, T74S, L89M, I93L  
  1730PLASMA Unknown    T12S, I15V, L19I, E35D, M36I, R41K, L63V, H69K, K70KR, T74S, L89M, I93L  
1736 1736PLASMA Unknown    T12S, G16A, L19I, E35D, N37S, R41K, L63P, H69K, V77I, I93L  
  1736CSF Unknown    T12S, G16A, L19IT, E35D, M36MI, N37NS, R41K, L63P, H69K, V77I, I93L  
1748 1748CSF Unknown    T12S, I15V, L19I, M36I, R41K, L63V, H69K, T74S, L89M, I93L  
  1748PLASMA Unknown    T12S, I15V, L19I, M36I, R41K, L63V, H69K, T74S, L89M, I93L  
1862 1862CSF Unknown    I15V, G17D, L19V, K20R, E35D, M36L, N37S, R41K, L63A, H69K, A71T, I93L  
  1862PLASMA Unknown    I15V, G17D, L19V, K20R, E35DN, M36L, R41K, L63A, H69K, A71T, I93L  
1876 1876CSF Unknown    T12S, I15V, L19I, N37S, R41K, D60E, Q61E, L63P, H69K, V77I, L89M, I93L  
  1876PLASMA Unknown    T12AS, K14R, I15V, N37S, R41K, K45KR, D60E, Q61E, L63P, H69K, V77I, L89M, I93L  
1884 1884CSF Unknown    I15V, L19I, E35D, M36L, N37E, R57K, D60E, Q61N, L63P, H69K, L89M, I93L  
  1884PLASMA Unknown    I15V, L19I, E35D, M36I, N37E, R57K, D60E, Q61D, L63P, I64L, H69K, L89M, I93L  
1895 1895CSF Unknown  M46MI  T12S, I15V, G16E, L19I, M36I, N37K, R41K, G68GD, H69K, L89M, I93L W42W*, V56VI 
  1895PLASMA Unknown    T12S, I15V, G16E, L19I, M36I, N37K, R41K, H69K, L89M, I93L  
1925 1925PLASMA Unknown    T12TS, K14KR, I15V, L19I, M36MIL, N37S, R41K, L63I, H69K, V77VI, L89IM, I93L  
  1925CSF Unknown    L10V, I15V, L19I, N37S, R41K, L63V, H69K, L89I, I93L  
1930 1930CSF Unknown    I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63S, H69K, I72T, L89I, I93L I84IT 
  1930PLASMA Unknown    L5LF, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63S, C67CW, H69K, I72T, L89I, I93L Q61Q* 
1972 1972CSF Unknown    K14KR, I15V, L19I, E35D, M36I, R41K, L63P, H69K, K70KR, L89LM, I93L  
  1972PLASMA Unknown    I15V, L19I, E35ED, M36I, R41K, K45KR, L63P, C67CW, H69K, I93L