Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Totmenin (2019)
Title Natural polymorphisms of HIV-1 integrase coding region in ARV-naive individuals in Novosibirsk region, Russia
Citation Direct Genbank Submission
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 25
NumPts 25
Subtype CRF63_02A1, A, CRF02_AG

 

Clinical IN Isolates


SubjectIsolateINIsWksINIMajorINIMinorCommonUnusual
122_NSK 122_NSK None    E11D, S24N, V31I, M50I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, V201I, L234I, S255N  
125_NSK 125_NSK None    E11D, K14R, S24N, V31I, V32I, L45V, M50I, I72V, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, V201I, T206S, T218I, L234I, S255N  
128_NSK 128_NSK None    E11D, K14R, S24N, V31I, M50I, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, K173R, V176L, V201I, L234I, S255N  
130_NSK 130_NSK None    E11D, S24N, V31I, M50I, T112V, S119P, T124S, T125A, G134N, K136Q, R187K, V201I, T218I, L234I, S255N  
131_NSK 131_NSK None    E11D, S24N, V31I, M50I, K111R, T112V, S119P, T124S, T125A, G134N, K136Q, R187K, V201I, T218I, L234I, S255N  
137_NSK 137_NSK None    E11D, S24N, V31I, M50I, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, V150A, V201I, T206S, L234I, S255N  
141_NSK 141_NSK None   T97A E11D, S24N, V31I, M50I, I72V, L74I, T112V, I113V, S119P, T122I, T124S, T125A, G134N, K136Q, V201I, L234I, S255N  
142_NSK 142_NSK None    K14R, S24N, V31I, D41E, M50I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, V165I, V201I, I203M, T218I, L234I, S255N  
143_NSK 143_NSK None    R20K, V31I, I72V, L74I, S119P, T124S, T125A, G134N, K136Q, D167E, G193E, V201I, T218I, L234I, S255N  
144_NSK 144_NSK None    V31I, L101I, T112V, T125A, G134N, I135V, K136T, V201I, T206S, L234I, S283G, D288N  
145_NSK 145_NSK None    E11D, K14R, S24N, V31I, M50I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, V201I, L234I, S255N  
146_NSK 146_NSK None    E11D, S24N, V31I, M50I, L74I, T112V, S119P, T122I, T124S, T125A, G134N, K136Q, V201I, L234I, S255N  
147_NSK 147_NSK None    E11D, S24N, V31I, K42R, M50I, T112V, I113V, S119P, T124N, T125A, G134N, K136Q, V201I, D232E, L234I, S255N  
148_NSK 148_NSK None    E11D, K14R, S24N, V31I, D41E, M50I, T112V, I113V, S119P, T124N, T125A, G134N, K136Q, V201I, K211R, T218I, L234I, S255N  
149_NSK 149_NSK None    E11D, K14R, S24N, V31I, M50I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, V201I, T218I, L234I, S255N  
150_NSK 150_NSK None    E11D, K14R, S24N, V31I, M50I, L74I, K111R, T112V, T124S, T125A, G134N, K136Q, V201I, T218I, L234I, S255N  
151_NSK 151_NSK None    R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255N  
153_NSK 153_NSK None    E11D, S24N, V31I, M50I, T112V, I113V, S119P, T124S, T125A, K136Q, V201I, T218I, L234I, S255N K7I 
154_NSK 154_NSK None    E11D, S17R, A23G, S24N, V31I, M50I, T112V, I113V, S119P, T124S, T125A, K136Q, V201I, T218I, L234I, S255N T122P 
157_NSK 157_NSK None    R20K, A21T, V31I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, L234I, S255N  
159_NSK 159_NSK None    K14R, S24N, V31I, D41E, M50I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, V165I, V201I, L234I, S255SN  
160_NSK 160_NSK None    E11D, K14R, S24N, V31I, D41G, M50I, T112V, S119P, T124S, T125A, G134N, K136Q, V201I, T218I, L234I, S255N  
229_NSK 229_NSK None    S17N, R20K, V31I, L63I, I72V, L74I, K111R, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T206S, T218I, L234I, S255N, D256E  
240_NSK 240_NSK None    E11D, S24N, V31I, E35EK, M50I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, V201I, T218TI, L234I, S255N V151VG 
304_NSK 304_NSK None    E11D, K14R, S24N, V31I, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, V201I, L234I, S255N