Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Alves (2019)
Title Estimating HIV-1 Genetic Diversity in Brazil Through Next-Generation Sequencing.
Citation Front Microbiol
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 26
NumPts 26
Subtype B, C, F

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
10HU-FURG 10HU-FURG TDF, 3TC EFV   V8I, K20R, V35T, E36A, T39D, S48T, V60I, K122E, I135R, I159V, K166R, I178M, T200E, R211K, V245Q, A272P, K277R, L283I, E291D, V292I, I293V, P294T, L301I, S322A, D324E, I329L, G335S, R356K, G359T, K366R, T369A, K390R, A400T, E404D, V435A, N447H, R448K, L452M, V466I, S468P, D471E, T477A, H483Q, L484I, L491S, Q507H, Q509K, S519N, K527T, K530R, V531I, A534S, A554S  
10HU-UFRJ 10HU-UFRJ TDF, 3TC EFV   V35I, I135T, A158S, I178M, I195L, T200A, E204D, K277R, P294Q, V317A, I329L, T377I, I382V, E404D, L452A, D460N, R461K, H483Y, L491S, L517I, Q547K, A554T  
12HU-UFRJ 12HU-UFRJ TDF, 3TC EFV   K49R, K122E, I135T, I142V, E169D, A272S, V292I, I293V, A376T, T386I, V435I, Q524E  
14HI 14HI AZT, 3TC None   E6D, D123E, S162C, D177E, Q207QE, K277R, I293V, K311R, E328D, Q334H, I341V, M357T, T377Q, K390R, A400T, V467I, S468P, K512Q, K530R  
14HU-FURG 14HU-FURG AZT, 3TC None   V35T, K49R, D123E, S162C, K173T, Q174R, D177E, I178M, T200A, Q207K, R211Q, V245L, E248D, A272P, K275Q, K277R, K281R, T286A, E291D, V292I, I293V, E297A, E312Q, I329V, Q334QL, G335N, T377R, K390R, E399D, A400T, K431T, V435A, L452K, R461K, V466A, S468F, D471E, T477A, Q480H, L491S, E492T, S519N, A534S K374A, K530N 
16HI 16HI AZT, 3TC None   I135T, Q207E, R211K, V245T, E248D, A272P, I293V, Q334L, A360T, A376T, S379C, K385R, T386I, K390R, V435A, R448K, V467I, S468P, H483N, L517V, S519N, A554T, V559I  
16HU-FURG 16HU-FURG TDF, 3TC EFV   V35T, E36A, T39E, S48T, K122E, D123N, E169D, K173A, D177E, T200A, Q207D, R211K, V245M, D250E, A272P, K277R, T286A, E291D, V292I, I293V, S322A, G335D, R356K, G359T, K366R, T377Q, S379C, K390R, A400T, E404D, V435A, F440Y, L452K, V467I, L469F, D471E, T477A, H483Q, L491P, S519N, K527S, K530R, A554N  
17HI 17HI AZT, 3TC None   V35T, T39L, R83K, T200A, R211K, A272P, K277R, E297A, I329L, F346C, R358K, K366R, A376T, A400T, D460N, R461K, H483Y  
17HU-FURG 17HU-FURG AZT, 3TC None   V35T, E36A, T39D, S48T, K122E, D123N, K173A, D177E, T200A, I202V, Q207N, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, I329L, Q334H, G335D, R356K, G359T, K366R, T377Q, E404D, V435A, L452M, V466I, S468P, D471E, H483Q, L491S, S519T, K530R, A534S, E546K, A554S  
18HI 18HI TDF, 3TC EFV   I135T, I142V, S162A, D177E, T200I, Q207E, R211K, K281R, L283I, I293V, P294S, I329L, R356G, T377R, S379G, T386V, E449D, R461K, S468P, H483C, K550R, A554S  
18HU-FURG 18HU-FURG TDF, 3TC EFV   V35A, T39A, K49R, D123E, S162C, K173I, Q174K, T200A, Q207K, R211Q, V245Q, E248D, A272P, T286A, E291D, I293V, E297A, I329V, G333E, Q334H, K374T, T377R, K388R, K390R, E399D, A400T, K431T, V435A, R461K, V466A, D471E, T477A, Q480H, L491S, E492K, S519N, L533M, A534S, E546A, V559I L452D, K530E 
19HI 19HI AZT, 3TC EFV   K20R, E29K, K32R, M41I, D123E, I135T, Q174R, D177E, T200S, R211K, V245K, K277R, I293V, E297K, I329L, Q334G, G335D, R356K, A376S, T386I, E413D, V435I, S468P, L517I, A554T Q197S 
1HU-FURG 1HU-FURG TDF, 3TC EFV   E28A, K32Q, V35T, E36A, T39E, S48T, K102R, K122E, D123N, I178M, T200A, E204K, Q207E, F214L, V245Q, E248D, A272Q, K277R, T286A, E291D, V292I, I293V, Q334E, T338S, E344D, R356K, G359T, T377L, V381I, K390R, K395R, E404D, V435A, E449D, L452M, V466I, D471E, H483Q, L491P, S519N, L525M, K527N, A534S, A554S  
20HI 20HI TDF, 3TC EFV   I135T, A158S, K166R, T200V, R211K, V245K, S251R, A272S, T286A, A288T, K311R, M357I, T386I, K388R, T403I, E404D, K527N, K530R, A554T, K558R  
20HU-FURG 20HU-FURG TDF, 3TC EFV   V35M, T39A, R83K, K104R, K122E, I135T, T165I, E169D, Q174K, G196E, I202V, F214L, A272P, K281R, E297R, L301I, V317A, D324E, G359S, T369A, A400T, Y405H, V435M, L452M, R461K, V466I, V467I, S468T, H483Y, A508G, L517V, Q520K, K527S, A554T  
2HU-UFRJ 2HU-UFRJ TDF, 3TC EFV M41L, T215L  V35E, T39A, V60I, K122E, D123N, I135T, I142V, D177E, I178L, T200A, Q207E, A272P, K275Q, V276T, I293V, D324E, Y339W, G359S, A360T, T386I, K390R, A400T, S468P, L469I, L491S, K512R, V559I  
3HU-FURG 3HU-FURG AZT, 3TC EFV   V35T, E36A, T39D, S48T, K122E, D123S, I202V, R211Q, V245Q, A272P, K277R, E291D, V292I, I293V, E297A, V317A, I329L, G335D, R356K, G359T, K366R, T377L, V381I, K390R, K395R, E404D, V435A, L452M, V466I, S468H, D471E, Q480H, H483Q, L491S, S519N, V531I, A534S, A554N, K558R  
3HU-UFRJ 3HU-UFRJ AZT, 3TC EFV   K11Q, I135T, I142V, K166R, T200I, V245M, A272P, I293V, A327V, M357A, A376T, T386V, S468P, H483Y, V559I  
4HU-UFRJ 4HU-UFRJ AZT, 3TC EFV   K49R, E79D, I142V, T165I, E169D, K173R, I202V, V245M, A272P, V292I, I293V, K311R, R356K, A376T, T386V, S468P, V559I  
6HI 6HI AZT, 3TC None   V35T, T39L, D123E, S162C, E169D, K173T, T200A, I202V, Q207R, L210M, R211T, V245Q, A272P, K277R, T286A, E291D, I293V, E297T, A304E, V317A, R356K, G359S, I375V, A376S, T377L, T386I, K390R, Q394L, E399D, A400T, K431T, A446S, E449G, L452E, V466A, S468F, D471E, T477A, Q480E, H483Q, L491S, S519N, A534S, V559I  
6HU-FURG 6HU-FURG TDF, 3TC None  K103N P9S, V35T, E36A, T39D, S48T, K102M, K122E, D123N, K173A, Q174K, D177E, Q197K, T200E, Q207E, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, I309L, Q334N, G335D, R356K, M357I, G359T, K366R, E370G, T377M, V381I, K390R, E404D, V435A, L452M, V466I, D471E, H483Q, L491P, V493A, L517I, S519N, Q524E, K527R, K530R, A534S, A554K S156P, Y457S 
6HU-UFRJ 6HU-UFRJ AZT, 3TC EFV   K122E, I135R, S162T, D177E, R211K, V245K, A272P, K281R, I293V, E297N, V314I, I329L, G335D, M357R, A376V, T386I, A400T, K431T, V458I, H483Y, L503M, L525M, A534T  
7HU-FURG 7HU-FURG TDF, 3TC None   V35T, E36A, T39D, K43R, S48T, K122E, D123S, I135T, K173A, Q174K, D177E, T200V, Q207N, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, E297A, R307K, R356K, G359T, K366R, T377V, K390R, K395R, A400S, E404D, V435A, L452N, V466I, D471E, H483Q, L491S, L517I, S519N, Q524L, K527N, K530R, A534S, A554S  
7HU-UFRJ 7HU-UFRJ AZT, 3TC EFV   P4H, V60I, T107S, V118I, D123E, I135M, S162A, R211G, F214L, E248T, A272P, K277R, T286A, V317A, P345Q, K347R, V365I, A376S, V381I, K390R, V467I, T470A, T497S, L503I, A508G, Q509H, L517I, I522V, Q524E  
8HU-FURG 8HU-FURG TDF, 3TC None   V35T, T39D, K43R, S48T, V60I, K122E, I135T, S162C, T200A, Q207E, V245Q, D250E, A272P, K275Q, K277R, E291D, V292I, I293V, G335D, R356K, M357R, G359T, K366R, T377Q, K390R, E404D, V435A, L452M, R461K, V466T, D471E, H483Q, L491P, S519N, K527R, K530R, A534S, A554N  
9HU-UFRJ 9HU-UFRJ AZT, 3TC None   V35T, K122E, D123E, S162C, E169D, K173T, I178L, T200A, Q207E, R211K, V245Q, E248D, A272P, K277R, E291D, V292I, I293V, E297T, A304E, V317A, R356K, G359S, I375V, A376S, T377L, T386I, K390R, Q394L, E399D, A400T, K431T, A446S, E449D, L452K, V466A, D471E, T477A, Q480E, H483Q, L491S, S519N, A534S, V559I