Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Onoriode Digban (2019)
Title Analyses of HIV-1 integrase gene sequences among treatment-naive patients in the Eastern Cape, South Africa.
Citation J Med Virol
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 12
NumPts 12
Subtype C

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
2RT None None   V21I, V35T, T39E, S48T, V60I, K104R, K122E, D123G, K173A, Q174K, I178M, T200A, Q207G, R211K, V245Q, A272P, K277R  
30 30RT None None   V35T, T39E, S48T, E53D, K122E, D123G, S163R, K173A, D177E, T200A, Q207A, R211K, V245Q, A272P W153G 
32 32RT None None  E138A V35T, E36A, T39E, S48T, K49R, K122E, D123G, S162C, E169K, K173E, Q174K, D177E, V179I, E194D, T200G, Q207E, R211K, W212G, L228F, V245Q, A272P, K277R I180H, D256Y 
50 50RT None None  E138Q, Y181C V8I, V35T, E36A, T39D, S48T, V60I, K101R, K122E, K173A, Q174K, D177E, I178V, T200A, Q207K, R211E, V245Q, Q278E  
65 65RT None None   V35T, T39K, S48T, V60I, K122E, D123G, K173R, D177E, I195L, T200A, Q207E, R211K, W229R, V241L, V245Q, L246V, D250E, A272P  
81 V81RT None None K70N K103S, V106M K20R, V35T, E36A, T39E, S48T, V60I, S68G, W88S, V90I, K102Q, K122E, D123G, K173A, D177E, I178L, T200A, E204K, Q207D, R211K, F214L, V245Q, L246V, L264I K73E, F87C, A114G 
V1 V1RT None None   V35T, T39A, E40D, K122E, D123N, A158S, K173A, I178M, Q197K, T200A, Q207N, R211K, V245Q, E248T, A272P, K277R  
V65 V65RT None None   V35T, E36A, T39E, E40D, S48T, V60I, I142V, K173T, Q174E, T200A, I202V, Q207E, R211K, V245E, E248V, A272P L210A 
V70 V70RT None None   V35T, T39E, S48T, V60I, K122E, D123G, S134R, E169D, K173A, Q174K, D177E, T200A, Q207A, R211K, V245Q, A272P V189L 
V83 V83RT None None M41L, L74I, M184V V106M, G190A, F227L T27S, V35T, T39E, S48T, V60I, S68G, K104R, L109I, D121H, K122E, K173T, D177E, I178L, T200A, E203A, Q207E, R211K, V245Q, A272P, V276I  
W3 W3RT None None K65R, M184V V106I, Y188L V35T, E36A, T39E, S48T, S68G, K122E, I135V, S162C, K173T, Q174K, V179I, T200A, Q207E, R211K, Y232H, V245Q, A272P, K277R  
W5 W5RT None None   P4H, V35T, T39R, S48T, V60I, K122E, D123G, S162C, K166R, K173A, Q174K, D177E, T200A, Q207E, V245Q, A272P, K277R