Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Acharya (2020)
Title Variability in HIV-1 Integrase Gene and 3'-Polypurine Tract Sequences in Cameroon Clinical Isolates, and Implications for Integrase Inhibitors Efficacy.
Citation Int J Mol Sci
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 100
NumPts 100
Subtype CRF02_AG, G, A, CRF11_cpx, F, CRF37_cpx, CRF18_cpx, A + G, D, CRF01_AE, CRF09_cpx

 

Clinical IN Isolates


SubjectIsolateINIsWksINIMajorINIMinorCommonUnusual
NA2CMR010 NA2CMR010 None    K14R, V31I, L45M, L74M, L101I, T112V, T124A, G134N, I135V, K136T, G163E, V201I, T206S, L234I D270Q 
NA2CMR011 NA2CMR011 None    K14R, D41N, A91T, L101I, K103R, T112V, S119R, T124A, T125A, G134D, G163E, D167E, V201I, T206S, I208L, L234I, S283G  
NA2CMR012 NA2CMR012 None    E11D, K14R, S24N, V31I, K34R, G106A, S119T, G134N, K136T, M154I, V201I, T206S, K211R, Q221T, L234I, S255N, D256E, S283G  
NA2CMR013 NA2CMR013 None    D6E, E10D, E11D, S24N, V31I, S39N, I72V, L74M, L101I, T112V, T124A, G134N, I135V, K136T, V201I, T206S, I208M, Q221N, L234I, D256E  
NA2CMR015 NA2CMR015 None    D6E, E10D, E11D, S24N, V31I, S39N, I72V, L74M, T112V, T124A, G134N, I135V, K136T, V201I, T206S, I208M, Q221N, L234I, D256E  
NA2CMR019 NA2CMR019 None    E11D, K14R, S24N, V31I, L63I, L74I, E96D, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218I, F223Y, L234I, R269K  
NA2CMR023 NA2CMR023 None    E11D, K14R, V31I, L101I, T112I, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218I, L234I, N254Q, S255G, R269K, S283G  
NA2CMR040 NA2CMR040 None    K14R, K34R, I72V, L74I, T93N, T112V, T124A, T125A, V126M, K136Q, V201I, T206S, K211R, T218I, Q221H, L234I, S283G  
NA2CMR044 NA2CMR044 None    V32I, L45LI, L63I, L74I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218I, K219Q, L234I, D288N  
NA2CMR045 NA2CMR045 None    V32I, L63I, L74I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218I, K219Q, L234I, D288N  
NA2CMR049 NA2CMR049 None    K14R, V31I, S57G, L74M, E96D, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, I208L, T218S, L234I, N254K, S255G, K258R, R269K, S283G  
NA2CMR053 NA2CMR053 None    K14R, S57G, L101I, T112I, T124A, T125A, G134N, K136T, V201I, T206S, T218I, L234I, M275V, S283G  
NA2CMR110 NA2CMR110 None    L101I, G106A, T112I, T124A, T125A, G134D, K136T, G163S, D167E, F185Y, V201I, T206S, I208L, T218I, L234V, N254K, S283G  
NA2CMR114 NA2CMR114 None    K14R, V31I, L74I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V165I, V201I, T206S, T218I, L234I, D256E, A265V, V281M, S283G, D286E, D288N  
NA2CMR125 NA2CMR125 None    K14R, D25E, V31I, M50T, I72V, L74I, L101I, K111T, T112I, S119T, T124A, T125A, G134N, I135V, K136T, G163A, V201I, T206S, L234I, D256E, S283G, D288N  
NA2CMR143 NA2CMR143 None    K14R, L28I, V32I, S39C, M50I, L63I, L74I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I  
NA2CMR145 NA2CMR145 None    E13D, L101I, T112V, T125V, K136Q, V201I, I208L, K211Q, T218I, K219N, N222K, L234I, S255N, D256E  
NA2CMR151 NA2CMR151 None    K14R, Y15F, D25E, V31I, S39C, L63I, L74I, L101I, T112I, T124A, T125A, G134N, I135V, K136T, F181Y, V201I, T206S, T218I, L234I  
NA2CMR152 NA2CMR152 None    K14R, V31I, M50T, I72V, L74I, L101I, K111T, T112I, T124A, T125A, G134N, I135V, K136T, G163A, V201I, T206S, L234I, D256E, S283G, D288N  
NA2CMR154 NA2CMR154 None    K14R, S17T, V31I, D55N, I72IV, G106A, T112I, I113V, S119P, T124A, T125A, V126M, K136Q, D167E, K173R, V201I, K211N, Q216H, Y227F, L234I, N254Q, S255G, S283G  
NA2CMR162 NA2CMR162 None    V31I, I60M, Y99F, L101I, T112V, T124A, T125A, G134N, I135V, K136T, G163S, V201I, T206S, L234I, R269K, S283G  
NA2CMR171 NA2CMR171 None    E11D, S24N, V31I, I72V, A91T, L101I, T112V, S119P, T122I, T125A, I135V, K136T, V201I, T218S, I220L, Q221H, N222T, L234I, R269K, D270H, R284G  
NA2CMR176 NA2CMR176 None    K14R, R20K, S24N, V31I, M50T, L63I, I72V, L74I, L101I, T112V, T122I, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, S283G  
NA2CMR183 NA2CMR183 None    E11D, K14R, R20K, V31I, I72V, L101V, K111T, T112V, T124A, T125A, G134N, I135V, G163E, V201I, T206S, T218S, L234I, S283G  
NA2CMR184 NA2CMR184 None    E11D, K14R, A21T, A23V, D25E, V31I, M50I, T112V, T124A, T125A, G134N, K136Q, D167E, V201I, L234I, S283G  
NA2CMR185 NA2CMR185 None    K14R, V31I, L101I, T112V, T124G, T125A, G134N, K136T, G163V, V201I, T206S, L234I, R269K, S283G  
NA2CMR188 NA2CMR188 None    D6E, E11D, K14R, S24N, V31I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, I208M, T218I, L234I, A265V, R269K, S283G  
NA2CMR189 NA2CMR189 None    E11D, K14R, R20K, S24N, V31I, I72V, L101V, K111T, T112V, T124A, T125A, G134N, I135V, G163E, V201I, T206S, L234I, S283G  
NA2CMR194 NA2CMR194 None    E11D, S24N, D25E, L101I, T112I, T124N, T125V, K136Q, K173R, V201I, Y227F, L234I, S255N, D256E, S283G  
NA2CMR195 NA2CMR195 None    S24G, L74I, L101I, T112V, T124A, T125A, G134D, K136T, V201I, T206S, Q221S, L234I, A265V, R269K, D278N, S283G  
NA2CMR200 NA2CMR200 None    K14R, D25E, V31I, D55N, I72V, L74I, T112V, T124A, T125P, G134N, K136T, K188R, T206S, L234I, S283G  
NA2CMR203 NA2CMR203 None    E11D, K14R, S24N, V31I, L63V, L74I, E96D, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, A265V  
NA2CMR206 NA2CMR206 None    K14R, R20K, V31I, L101I, T112I, T124G, T125A, G134N, K136T, V201I, T206S, L234I, S283G  
NA2CMR208 NA2CMR208 None    K7R, E11D, V31I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, F181L, V201I, T206S, T218I, L234I, I268V  
NA2CMR209 NA2CMR209 None    K14R, V31I, Y99L, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, R269K, D286N  
NA2CMR210 NA2CMR210 None    E11D, K14R, V31I, Y99F, T112V, T124N, T125A, G134N, I135V, V201I, T206S, L234I, D256E, S283G  
NA2CMR211 NA2CMR211 None    E11D, K14R, V31I, L74I, G94A, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, S283G, R284G, D288N  
NA2CMR212 NA2CMR212 None    K14R, V31I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, D256E, R269K  
NA2CMR216 NA2CMR216 None    L101I, T112I, T125V, K136Q, G163S, I182V, V201I, L234I, S255N, D256E  
NA2CMR217 NA2CMR217 None    K14R, R20K, V31I, L101I, T112V, T124N, G134N, K136T, G163E, V201I, T206S, L234I, S255N, D256E, S283G  
NA2CMR219 NA2CMR219 None    E11D, K14R, S24N, D25E, L63I, L74I, A91E, L101I, T112I, S119R, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218I, L234I  
NA2CMR220 NA2CMR220 None    K14R, V31I, S39C, L101I, T112V, S119R, T124A, T125A, G134N, I135V, K136T, D167E, F181Y, V201I, T206S, Q216H, Q221S, L234I, S283G  
NA2CMR221 NA2CMR221 None    K14R, A21T, I72V, L74I, L101I, T112I, T124S, T125A, G134N, I135V, K136T, V201I, T206S, I208L, Q221T, L234I, R269K, S283G, R284G, D286A  
NA2CMR222 NA2CMR222 None    E11D, S24N, V31I, I72V, K111R, T112V, T124A, T125A, G134D, I135V, V165I, V201I, T206S, L234I, S283G  
NA2CMR223 NA2CMR223 None   E157Q K14R, L101I, T112V, T124A, T125A, G134N, I135V, K136T, K160Q, V201I, T206S, L234I, I268L, S283G  
NA2CMR244 NA2CMR244 None    K14R, S24H, L28I, S39C, L45I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, D167E, V201I, T206S, L234I, R269K  
NA2CMR251 NA2CMR251 None    E11D, D25E, V31I, L101I, T124A, T125A, G134N, I135V, K136T, I200M, V201I, T206S, L234I, S283G  
NA2CMR253 NA2CMR253 None    K14R, A21T, V32I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218I, L234I  
NA2CMR254 NA2CMR254 None    K14R, V31I, L74M, L101I, T112V, S119T, T124A, T125A, G134N, I135V, K136T, I200L, V201I, T206S, T218I, L234I, D256E, S283G  
NA2CMR255 NA2CMR255 None    E11D, K14R, Y15F, A21T, V31I, L74I, A91E, L101I, G106A, T112V, S119R, T124A, G134N, I135V, K136T, K188R, T206S, L234I, S283G  
NA2CMR256 NA2CMR256 None    S17N, I60V, L74I, L101I, K111T, T112V, S119A, T125A, G134N, I135V, K136T, V165I, V201I, A205S, K211R, E212H, K215Q, L234V, D256E, I268L, S283G  
NA2CMR265 NA2CMR265 None    K14R, V31I, E35EK, S39C, I60M, I72T, T112V, S119P, T124A, T125A, I135V, K136T, V201I, T206S, D207E, Q216H, Y227F, L234I, N254G, D270H, S283G, R284G  
NA2CMR305 NA2CMR305 None    E11D, E13D, S17T, M50I, L74I, A91E, L101I, T112V, S119T, T124A, T125A, G134D, I135V, K136T, V201I, T206S, I208M, K211Q, E212A, T218I, Q221K, N222K, L234V, S255N, R269K, S283G  
NA2CMR318 NA2CMR318 None    K14R, V31I, L101I, T112V, T124A, T125A, G134N, K136T, V165I, R187K, V201I, T206S, K211R, L234I, S283G I73T, I161S 
NA2CMR328 NA2CMR328 None    E11D, A21T, V31I, D41N, M50I, I60V, L63I, I72V, L74I, E96D, L101I, G106A, T112V, I113V, S119T, T124A, T125A, G134D, K136Q, V201I, T218I, L234I, S255D, S283G, R284G, D288N D207H 
NA2CMR331 NA2CMR331 None    E11D, E13D, A21T, D41N, M50I, L101I, T112V, T124G, T125A, K136Q, D167E, V201I, T218I, L234I, D256E, I268L, S283G  
NA2CMR334 NA2CMR334 None    K14R, V31I, Y99F, L101I, T112I, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218I, L234V, N254K, S255X, D256E, S283G  
NA2CMR501 NA2CMR501 None    K14R, V31I, E96D, L101I, G106A, T124A, T125A, G134N, I135V, K136T, V180A, V201I, T206S, L234I, R269K  
NACMR008 NACMR008 None    K14R, V31I, L74M, L101I, T112V, S119T, T124A, T125A, G134N, I135V, K136T, I200L, V201I, T206S, L234I, D256E, S283G  
NACMR013 NACMR013 None    E10G, K14R, V31I, S57G, L101I, T112V, T124A, T125A, K127Q, G134N, I135V, K136T, V201I, T206S, I208M, T218I, L234I, D256E, S283G  
NACMR019 NACMR019 None   T97A K14R, R20K, Q44H, L101I, T112V, T124A, T125A, G134N, K136T, G193E, S195C, V201I, Y227F, L234I, S255N, D256E, S283G, D288N  
NACMR025 NACMR025 None    K14R, R20K, V31I, L101I, T112V, S119T, T124A, T125A, G134N, I135V, K136T, F185Y, V201I, T206S, L234I, I268L, S283G  
NACMR036 NACMR036 None    K14R, V31I, M50T, L101I, T112V, T124A, T125A, G134D, I135V, K136T, K188R, V201I, T206S, L234I, S283G, R284G, D288N  
NACMR037 NACMR037 None    K14R, S17C, L74I, L101I, T112I, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, D270N  
NACMR039 NACMR039 None    E11D, E13D, V32I, L63I, I72V, L74I, Y99L, L101I, K103R, T112V, T124A, T125A, G134D, I135V, K136T, I200L, V201I, T206S, T218I, L234I, D278N, S283G  
NACMR050 NACMR050 None    K14R, V31I, L101I, T112V, T124A, T125A, G134N, K136T, V165I, R187K, V201I, T206S, K211R, L234I, S283G I73T, I161S 
NACMR052 NACMR052 None    K14R, V31I, L74M, L101I, T112V, T124A, T125A, G134N, I135V, K136T, I200L, V201I, T206S, L234I, D256E, S283G  
NACMR055 NACMR055 None    K14R, R20K, V31I, L101I, T112V, S119T, T124A, T125A, G134N, I135V, K136T, F185Y, V201I, T206S, L234I, I268L, S283G  
NACMR057 NACMR057 None    S17N, S39N, L101I, T112M, T125A, G134N, K136T, V165I, V201I, T206S, D207E, K211R, L234I, D256E, M275V, S283G  
NACMR067 NACMR067 None    E11D, K14R, A21T, V31I, I72V, L101I, T112V, T124A, T125A, G134S, K136Q, D167E, V201I, I208L, T218I, L234I, S255D, D256E, S283G, D286N  
NACMR069 NACMR069 None    K14R, V31I, M50T, L101I, T112V, T124A, T125A, G134D, I135V, K136T, K188R, V201I, T206S, L234I, S283G, R284G, D288N  
NACMR073 NACMR073 None    K14R, V31I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, K173R, V201I, T206S, L234I, R269K, D278E, S283G  
NACMR083 NACMR083 None   T97A K14R, V31I, L74M, L101I, T112V, T124A, T125A, V126A, G134D, K136T, V201I, T206S, I208L, T218I, L234I, A265V, R269K, D286N  
NACMR084 NACMR084 None    K14R, A21T, V31I, I72V, L101I, T112V, T124A, T125A, G134N, K136Q, V165I, D167E, V201I, T206S, I208L, E212A, L234I, S255D, S283G  
NACMR086 NACMR086 None    K14R, A21T, V32I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218I, L234I  
NACMR088 NACMR088 None    V31I, L63I, L74I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218I, L234I, A265V, R269K, D279G  
NACMR089 NACMR089 None   E157Q E11D, V31I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, K160Q, V201I, T206S, K219Q, L234I, D256E, S283G  
NACMR090 NACMR090 None   E157Q K14R, L45I, L101I, T112V, S119G, T122I, T124A, T125A, G134N, K136T, K160Q, V201I, T206S, L234I, D256E, I268L, S283G, R284G, D288N  
NACMR091 NACMR091 None   E157Q E11D, K14R, R20K, L28I, S39C, L45Q, Q95P, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, R269K, S283G  
NACMR092 NACMR092 None    K14R, V31I, I72V, L101I, T112V, T124A, T125A, G134N, K136T, V165I, R187K, V201I, T206S, K211R, L234I I161S 
NACMR095 NACMR095 None    K14R, S39C, S57G, Q95H, E96ED, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, R269K L242F 
NACMR098 NACMR098 None    K14R, S39C, S57G, Q95H, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, R269K  
NACMR100 NACMR100 None    E11D, R20G, S24N, V31I, D41N, I72V, G106A, T112V, T124A, T125A, G134D, I135V, V165VI, V201I, T206S, I208IL, K211KR, L234I, S283G  
NACMR101 NACMR101 None    K14R, R20RK, K34KR, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218I, L234I, A265V, S283G  
NACMR102 NACMR102 None    K14R, S24H, L28I, S39C, L45I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, D167E, V201I, T206S, L234I, R269K  
NACMR104 NACMR104 None    K7Q, A23V, M50I, I72V, L74M, L101I, T112V, T124A, T125A, V126A, G134N, V165I, I208L, T218K, I220L, Y227F, L234I, S255N, S283G  
NACMR105 NACMR105 None    V31I, L74I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, D167E, F181L, V201I, T206S, T218S, L234I R107K 
NACMR106 NACMR106 None    K14R, V31I, I72V, L74I, T112V, T124A, T125A, G134D, K136T, V201I, T206S, T218I, L234I, A265V, R269K, D278N, S283G  
NACMR107 NACMR107 None    K14R, V31I, L101I, T112V, T124A, T125A, G134N, K136T, V165I, R187K, V201I, T206S, K211R, L234I, S283G I73T, I161S 
NACMR109 NACMR109 None    E11D, K14R, S24N, V31I, I72V, T112V, T124A, T125A, V126I, G134D, I135V, V165I, V201I, T206S, L234I, S283G  
NACMR111 NACMR111 None    K14R, V31I, Y99F, L101I, T112I, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218I, L234V, N254K, S255X, D256E, S283G  
NACMR112 NACMR112 None    K14R, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218I, L234I, A265V, S283G E246K 
NACMR113 NACMR113 None    E11D, S24N, V31I, T93S, L101I, T112V, T124A, T125V, G134N, I135V, D167E, V201I, T206S, I208L, L234I, R284G  
NACMR120 NACMR120 None    K14R, A21T, V31I, L45Q, L101I, T112I, T124A, T125A, G134D, K136Q, D167E, V201I, I220V, L234I, S283G, D288N  
NACMR123 NACMR123 None    K14R, L28I, P30A, L45V, I72V, L101I, T112I, I113V, T124S, G163E, V201I, K211R, Y227F, L234I  
NACMR125 NACMR125 None   E157Q K14R, L45I, L101I, T112V, S119G, T122I, T124A, T125A, G134N, K136T, K160Q, V201I, T206S, L234I, D256E, I268L, S283G, R284G, D288N  
NACMR136 NACMR136 None    K14R, V31I, L101I, K111T, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, I208L, K211KR, E212EQ, L234I, S283G, D286V  
NACMR141 NACMR141 None    E11D, K14R, S24H, V31I, L101I, K111Q, T112V, T125A, G134N, I135V, K136T, V201I, T206S, L234I, R269K, S283G  
NACMR150 NACMR150 None   E157Q E11D, V31I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, K160Q, V201I, T206S, K219Q, L234I, D256E, S283G, R284K Q285K 
NACNR183 NACNR183 None    E11D, R20K, S24N, V31I, I72V, A91V, K111R, T112V, T124A, T125A, G134D, I135V, V165I, V201I, T206S, L234I, S283G