Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Sebastião (2019)
Title Genetic diversity and drug resistance of HIV-1 among infected pregnant women newly diagnosed in Luanda, Angola.
Citation PLoS ONE
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 34
NumPts 34
Subtype C, F, A, G, H, CRF02_AG, D, A + G

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
P1 P1 None None   K20R, L34I, V35T, T39I, E40D, K49R, I50V, V60I, K122E, T165V, Q174G, D177E, I178L, T200A, E204Q, Q207E, R211K, F214L, I244V, V245K, D250E, A272P, K281R, T286A, A288S, I293V, L295F, E297K, E328D, Q334H, G335D  
P10 P10 None None  V106I, G190A V35T, E36D, V60I, K122E, D123N, I135T, S162H, K166R, K173S, D177E, V179I, I195L, T200E, Q207A, R211S, V245K, E248A, A272P, K275R, V276I, T286A, E291D, V292I, I293V, P294T, E297A, S322T, G335D Q174C 
P11 P11 None None   V35AT, E36EAD, D123E, S162C, K173A, Q174K, P176T, T200AE, Q207E, R211K, V245Q, E248N, A272S, T286A, E291D, V292I, I293V, P294T, E297A, K311Q, V317AT L295V 
P12 P12 None None  K103N, E138A, P225H V35T, D121Y, K122E, D123E, S162C, K173T, Q174K, D177E, V179I, T200A, R211K, V245Q, D250E, S251D, T286A, E291D, V292I, I293V, E297A, H315Y, I326V, Q334H N81I 
P13 P13 None None   V21I, V35T, T39E, K49R, V60I, K102Q, D121H, K122E, D123S, Q174QE, D177E, I178M, T200E, E204N, Q207A, R211K, P243S, I244V, V245K, A272S, K277KR, L283I, T286A, E291D, V292I, I293V, E297DN  
P14 P14 None None   V35T, T39A, S48T, D177E, T200A, Q207EG, R211K, F214L, P243PS, V245X, E248X, D250DE, A272AS, R284K, E291D, V292I, I293V, K311R, I329V, Q334DN, G335E  
P15 P15 None None   V35T, E36A, T39E, S48T, K122KR, D123DN, I142V, K173IL, D177E, Q197P, T200A, Q207G, R211RK, V245Q, D250E, S251SI, A272P, K277R, T286TA, E291D, I293V, Q334D, G335D  
P16 P16 None None   V35T, E36A, T39D, S48T, K122E, K173A, Q174K, D177E, I178L, T200A, Q207EG, R211K, V245H, E248D, D250E, K277R, T286A, E291D, V292I, I293V, Q334H, G335D  
P18 P18 None None   E28K, K32E, V35K, E36A, T39E, S48T, K49KR, D123N, E169X, K173KE, D177E, T200A, Q207E, R211RK, V245K, D250E, S251N, A272AP, K277R, T286A, E291D, V292I, I293V, A304E, K311R, D324E, Q334H, G335D  
P19 P19 None None  E138A T27TA, V35K, E36A, T39E, S48T, V60I, V118I, K122E, I135V, K173IT, Q174KR, T200A, Q207E, R211RK, F214L, P243S, V245Q, E248D, A272P, K277R, Q278H, T286A, V292I, I293V, E297K, K311R, I329V, Q334N, G335D  
P2 P2 None None   V35T, T39A, E40D, I135L, S162A, K173T, D177E, T200A, Q207D, V245EK, S251SC, K275R, V276VI, T286A, E291D, V292I, I293V, P294T, S322T, G335D  
P20 P20 None None  E138A K20R, V35T, E36A, T39E, S48T, A98S, K122E, D123N, K173R, D177E, I178V, T200A, E204K, Q207E, R211K, F214L, P243A, V245Q, A272P, K277Q, Q278K, E291D, V292I, I293V, Q334D  
P21 P21 None None   V35T, K43KQ, E44ED, K49R, I50V, V60I, D121C, K122E, I135V, S162C, K173KR, D177E, I178M, V179I, T200A, E204K, Q207E, P243AS, V245Q, D250E, A272P, K277R, L283LI, I293V, E297T, Q334H  
P22 P22 None None   V35T, T39Q, V60I, K104KR, D121H, K122E, D123S, I135T, I142V, K173A, Q174K, D177E, T200A, Q207E, R211K, F214L, V245K, K249Q, K275Q, E291D, V292I, I293V, E297A, P321S, D324E, I329V, Q334L, G335D  
P23 P23 None None   K32I, V35T, T39K, T165TI, K173LS, Q174K, D177E, T200A, Q207A, R211S, F214L, P243PS, V245K, D250E, S251HQ, A272S, K281R, E291D, V292I, I293V, E312T, G335D  
P24 P24 None None   V35T, E36A, T39D, S48T, V60I, K122E, D123G, K173A, Q174K, D177E, T200A, Q207E, K281R, T286A, V292I, I293V, Q334H, G335D  
P26 P26 None None  G190A P4PT, E6D, V21I, T27S, V35T, T39R, E40D, K43Q, K49R, V60I, K102N, D121H, K122E, I135T, E169D, D177E, V179I, G196K, T200A, Q207A, R211K, I244V, V245K, D250E, A272Q, T286A, V292I, I293V, L301M, G335D  
P27 P27 None None M41L, D67N, T69D, T215S Y181I K32KI, V35T, T39X, K43KE, V60I, A98S, K122E, I135V, T139KR, K173T, Q174K, D177G, T200A, Q207E, R211K, D218E, V245Q, E248D, D250E, S251D, T286A, E291D, V292I, I293V, E297AS, I329IV, Q334L, G335D K102DE 
P28 P28 None None  E138A V35T, E36A, T39E, E40D, S48T, V118I, T139A, K173T, Q174G, V179I, T200A, Q207E, R211K, F214L, V245Q, E248N, A272P, K275R, Q278H, K281R, T286A, E291D, V292I, I329V, G335D  
P3 P3 None None   T27S, V35T, T39E, S48T, K122E, D123S, I135T, S162C, K173A, Q174K, D177E, I178IM, T200E, Q207A, R211K, V245Q, E248N, D250E, S251X, A272P, K275R, K277R, E291D, V292I, I293V, Q334N, G335D  
P30 P30 None None   V35T, T39K, K122E, D123E, I135V, S162C, K173T, Q174E, T200A, V245Q, D250N, S251D, A272P, K275R, Q278N, K281R, T286A, E291D, V292I, I293V, E297A, I329V, G335E  
P31 P31 None None   E6N, V35T, T107S, K122E, D123DN, I142IV, S162C, K173AT, I178IV, T200A, Q207EG, R211K, V245Q, E248D, D250E, S251D, A272P, K277R, Q278H, T286A, V292I, I293V, E297A, I329V, Q334P, G335D  
P33 P33 None None  E138A K11S, V35T, T39N, E40D, V60I, K64R, K104R, K122E, D123N, K173A, Q174K, I180V, T200A, Q207E, R211K, V245Q, A272P, L283I, V292I, I293V, P294A, E297R, D324E, G335D S322N 
P34 P34 None None   V35T, T39M, V60I, K102Q, K103Q, D121H, K122E, I135T, K173S, Q174K, D177E, D192N, T200E, I202V, Q207N, R211K, V245K, K249Q, S251V, A272P, K275Q, T286A, I293V, E297K, E312N, D324E, G335D  
P35 P35 None None  E138G K11R, V35T, T39N, E40D, K101Q, V118I, K122E, D123S, A158S, K173A, Q174K, D177E, I178L, T200R, Q207A, R211S, F214L, V245Q, E248D, A272P, K281R, E291D, V292I, I293V, L301LF, K311R, E312N, I326V, G335D  
P38 P38 None None   I2V, E6D, K20R, V35T, E40D, K49R, V60I, I135V, S162A, K173T, Q174K, D177E, T200A, E204K, Q207E, P243S, V245K, A272G, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D  
P39 P39 None None   V35T, E40ED, K49KR, D123E, S162C, E169EA, K173A, Q174K, T200A, Q207E, R211K, V245Q, E248D, A272AP, I274IV, K275KQ, Q278X, K281R, E291D, V292I, I293V, E297A, E312EK, Q334H, G335D  
P4 P4 None None  V179E V35T, T39A, K49R, K122E, I135V, A158S, S162C, E169D, K173R, Q174K, D177E, T200A, Q207D, R211K, V245Q, E248D, V261I, A272P, T286A, E291D, V292I, I293V, E297A, P313S, V317A W266W* 
P41 P41 None None  K103N V35T, T39E, S48T, V60I, D121Y, K122E, D123DG, I142V, D177E, I178L, T200A, Q207EK, R211K, V245R, E248D, D250E, A272P, K281R, E291D, V292I, I293V, P294PS, Q334N, G335D  
P5 P5 None None   V35T, D123E, I135X, S162C, K173A, Q174R, I178L, T200A, Q207DE, R211K, V245Q, E248D, A272S, K277R, Q278N, T286A, E291D, V292I, I293V, E297A, K311R  
P6 P6 None None   V35T, E36A, T39E, S48T, K122E, D123S, K173A, D177E, I178M, T200A, Q207N, R211RK, P243ST, V245KQ, E248ED, D250E, K275Q, E291D, V292I, I293V, Q334H, G335D  
P7 P7 None None  E138A T27S, V35T, D121Y, K122E, I135V, I142IT, S162C, K173I, Q174K, D177E, I178IL, V179I, T200A, Q207E, R211K, V245Q, E248D, D250X, E291D, V292I, I293V, D324E, Q334H, G335D  
P8 P8 None None  V108I V35T, T39E, S48T, K122E, D123N, K173T, D177E, T200A, I202V, Q207R, R211K, P243A, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, Q334E  
P9 P9 None None   V35T, E36A, T39E, E40D, S48T, K122E, I135V, S162Y, K173I, Q174K, D177E, I178M, T200A, Q207E, R211RK, P243T, V245E, V261VG, A272P, E291D, V292I, S322A, D324E, Q334N, G335D