Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Saini (2012)
Title Resistance-associated mutations in HIV-1 among patients failing first-line antiretroviral therapy.
Citation J Int Assoc Physicians AIDS Care (Chic)
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 32
NumPts 32
Subtype C

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
MAMC-IND-04 MAMC-IND-04 NRTI NNRTI K70KR, M184MV, T215Y  V35T, T39E, S48T, K102S, K122E, D123S, K173A, D177K, I195IK, T200A, Q207E, R211K, V245Q  
MAMC-IND-1011 MAMC-IND-1011 NRTI NNRTI D67DG, V75VI F227FL V35T, T39E, S48T, K102S, K122E, D123NS, K173A, D177E, T200A, Q207E, R211K S117SL, Q161Q* 
MAMC-IND-1019 MAMC-IND-1019 NRTI NNRTI   V35T, T39E, S48T, K102S, K122E, D123NS, K173A, D177E, T200A, Q207E, R211K S117SL 
MAMC-IND-1280 MAMC-IND-1280 NRTI NNRTI V75I, F116Y, Q151M, M184V, T215Y G190A V8I, V35T, T39D, V60I, S68G, D121Y, K122E, I132L, I135T, K166R, K173A, D177E, T200A, Q207E, R211K  
MAMC-IND-1444 MAMC-IND-1444 NRTI NNRTI M41L, D67G, K70R, M184V, T215Y Y181I V35T, T39N, V60I, K102Q, K103R, K122E, I135T, K166R, K173A, D177E, T200A, Q207E  
MAMC-IND-1445 MAMC-IND-1445 NRTI NNRTI D67N, M184V, T215S V106M, G190A K32KR, V35T, T39E, V60I, K122E, M164MI, K173A, D177E, T200A, Q207E, K223R, L228H  
MAMC-IND-1446 MAMC-IND-1446 NRTI NNRTI M41L, M184V, T215Y Y181C V35T, T39E, E44D, S48T, V60I, S68G, I135R, K173A, D177E, T200A, Q207E, R211K  
MAMC-IND-1460 MAMC-IND-1460 NRTI NNRTI M41L, D67G, T69D, K70R, M184V, T215F V106VIM, E138G, V179D, Y181I K20R, K32I, V35T, T39N, S48ST, V60I, K102Q, K103R, V118VI, K122E, D123DN, I135R, K166R, K173A, T200A, Q207E, F214L  
MAMC-IND-16 MAMC-IND-16 NRTI NNRTI K70KR, T215Y Y181YC V35T, T39AE, S48T, K102S, K122E, D123S, K173A, D177K, I195IK, T200A, Q207E, R211K, V245Q  
MAMC-IND-17 MAMC-IND-17 NRTI NNRTI D67DG, K70KR, M184MV, K219KQ  V35T, T39AE, S48T, K102S, V118VI, K122E, D123S, K173A, D177K, I195IK, T200A, Q207E, R211K, V245Q  
MAMC-IND-222 MAMC-IND-222 NRTI NNRTI D67DN, T215Y, K219KQ Y181YC V35T, T39E, S48T, K102S, K122E, D123S, K173A, D177K, I195IK, T200A, Q207E, R211K, V245Q  
MAMC-IND-242 MAMC-IND-242 NRTI NNRTI M41L, D67N, M184V, T215Y K103N E28K, K32E, V35T, T39DN, E44D, S48T, K49KR, V60I, V118VI, K122E, D123N, I135T, E169A, K173A, Q174K, N175H, D177E, I178V, T200V, K201M, E203ED, Q207A, H208HY, R211K  
MAMC-IND-283 MAMC-IND-283 NRTI NNRTI M184MI  V35T, T39E, E40D, S48T, V60I, K122E, D123N, I135V, K173A, Q174K, D177E, T200A, Q207A, R211K  
MAMC-IND-287 MAMC-IND-287 NRTI NNRTI M41L, M184V, T215Y G190A S3C, V35T, T39E, V60I, K122E, T139R, K173A, D177E, V179I, T200A, Q207E  
MAMC-IND-306 MAMC-IND-306 NRTI NNRTI M184MV Y181YC V35T, T39E, S48T, K102S, K122E, D123S, K173A, D177K, I195IK, T200A, Q207E, R211K, V245Q  
MAMC-IND-327 MAMC-IND-327 NRTI NNRTI D67DN, K70KR, M184MV, K219KQ  V35T, T39AE, S48T, K102S, K122E, D123S, K173A, D177K, I195IK, T200A, Q207E, R211K, V245Q  
MAMC-IND-33 MAMC-IND-33 NRTI NNRTI M41L, M184V, L210W, T215Y K101P, G190A S3C, V35T, T39D, E44D, V60I, V90I, D121C, K122E, T139R, S162A, K173A, D177E, V179I, T200A, Q207E  
MAMC-IND-44 MAMC-IND-44 NRTI NNRTI M184MI  V35T, T39E, E40D, S48T, V60I, K122E, D123N, I135V, K173A, Q174K, D177E, T200A, Q207A, R211K  
MAMC-IND-470 MAMC-IND-470 NRTI NNRTI M184MV  V35T, T39E, S48T, K102S, V118VI, K122E, D123S, K173A, D177K, I195IK, T200A, Q207E, R211K, V245Q  
MAMC-IND-592 MAMC-IND-592 NRTI NNRTI D67DN, K70KR, T215Y, K219KQ Y181YC V35T, T39E, S48T, K102S, K122E, D123S, K173A, D177K, I195IK, T200A, Q207E, R211K, V245Q  
MAMC-IND-613 MAMC-IND-613 NRTI NNRTI   V35T, T39E, S48T, K102S, K122E, D123NS, K173A, D177E, T200A, Q207E, R211K  
MAMC-IND-643 MAMC-IND-643 NRTI NNRTI D67N, T69D, K70R, M184V, K219Q V106M, G190A, H221Y, F227L K32KR, V35T, T39E, V60I, L109I, D121H, K122E, M164MI, K173A, Q174QR, D177E, I178F, T200A, I202V, E203K, Q207E, K223R, L228H E233V 
MAMC-IND-674 MAMC-IND-674 NRTI NNRTI M41L, M184V, T215Y  E28K, V35T, T39D, S48T, V60I, V118VI, K122E, I135T, E169A, K173A, N175H, D177E, I178V, T200V, K201M, Q207A, R211K  
MAMC-IND-74 MAMC-IND-74 NRTI NNRTI M41L, M184V, T215Y  K20KR, V35T, T39D, E44D, S48T, V60I, S68SG, V118VI, K122KE, K173A, D177E, T200A, Q207E, R211K  
MAMC-IND-77 MAMC-IND-77 NRTI NNRTI D67DN, M184MV, T215NY, K219KQ Y181YC V35T, T39AE, S48T, K102S, K122E, D123S, K173A, D177K, I195K, T200A, Q207E, R211K, V245Q  
MAMC-IND-82 MAMC-IND-82 NRTI NNRTI M41L, Q151M, M184V, T215Y G190A V8I, K20KR, V35T, T39D, V60I, S68SG, D121Y, K122E, I135T, K166R, K173A, D177E, T200A, Q207E, R211K  
MAMC-IND-828 MAMC-IND-828 NRTI NNRTI M184MI  V35T, T39E, E40D, S48T, V60I, K122E, D123N, I135V, K173A, Q174K, D177E, T200A, Q207A, R211K  
MAMC-IND-850 MAMC-IND-850 NRTI NNRTI M184MV Y181YC V35T, T39AE, S48T, K102S, K122E, D123S, K173A, D177K, I195IK, T200A, Q207E, R211K, V245Q  
MAMC-IND-894 MAMC-IND-894 NRTI NNRTI M41ML, M184V, T215Y V108I, Y181C, H221Y V35T, T39E, S48T, K49R, V60I, S68SG, I135R, K173A, D177E, V179I, G196E, T200A, Q207E, R211K, F214L  
MAMC-IND-904 MAMC-IND-904 NRTI NNRTI M41ML, M184MV, T215Y  V35T, T39E, S48T, K102S, K122E, D123S, K173A, D177K, I195IK, T200A, Q207E, R211K, V245Q  
MAMC-IND-91 MAMC-IND-91 NRTI NNRTI   V35K, T39D, S48T, V60I, K122E, I135T, S162A, F171L, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, Q242H, V245Q  
MAMC-IND-950 MAMC-IND-950 NRTI NNRTI M41L, D67N, M184V, T215Y K103N, E138Q K20R, V35T, T39E, E44D, S48T, V60I, V118I, K173A, D177E, G196E, T200A, Q207E, R211K