Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Prellwitz (2013)
Title HIV behind bars: human immunodeficiency virus cluster analysis and drug resistance in a reference correctional unit from southern Brazil.
Citation PLoS ONE
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 38
NumPts 38
Subtype C, B

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
P12 P12 Unknown Unknown   V35T, E36A, T39D, K43R, D123E, K173A, D177E, T200V, Q207X, R211K, W229X, M230X, G231X, Y232X, E233X, L234X, H235X, P236X, D237X, K238X, W239X, T240X, V241X, Q242X, P243X, I244X, V245X, L246X, P247X, E248X, K249X, D250X, S251X, W252X, T253X, V254X, N255X, D256X, I257X, Q258X, K259X, L260X, V261X, G262X, A272P, K277R, T286A, V292I, I293V, E312EAG, I329L, G335D, R356K, M357K, G359T, K366R, K390R, E399ED, E404D, V435A, E449ED, L452M, V466I, D471E, T477A, H483Q, L484LI, L491S, E492EA, E514ED, S519N, K530G, A534S, A554N, K558R  
P13 P13 Unknown Unknown   K20R, K122E, I135T, N136X, N137X, E138X, T139X, P140X, G141X, I142X, R143X, Y144X, Q145X, Y146X, N147X, V148X, L149X, P150X, Q151X, G152X, W153X, K154X, G155X, S156X, P157X, A158X, I159X, T200I, F214L, I293V, K311R, R358K, A376T, T386V, K390R, A400S, T403M, L452S, H483Y, K527Q  
P14 P14 Unknown Unknown   V35T, E36A, T39D, S48T, K122E, D123N, A158S, K173T, D177E, T200E, R211K, H221X, Q222X, K223X, E224X, P225X, P226X, F227X, L228X, W229X, M230X, G231X, Y232X, E233X, L234X, H235X, P236X, D237X, K238X, W239X, T240X, V241X, Q242X, P243X, I244X, V245X, L246X, P247X, E248X, K249X, D250X, S251X, W252X, T253X, V254X, N255X, D256X, I257X, Q258X, K259X, L260X, V261X, G262X, K263X, L264X, N265X, W266X, A267X, S268X, Q269X, I270X, Y271X, A272X, G273X, I274X, K275X, K277R, K281R, T286A, E291D, V292I, I293V, P294T, G335D, R356K, G359T, K366R, A376T, T377Q, V381I, K390R, A400T, E404D, L452M, V466S, D471E, H483Q, L491S, S519N, K530R, A534S, A554K  
P16 P16 Unknown Unknown   V8I, K32R, V35K, T39A, K104R, K122E, D123S, I135T, N137X, E138X, T139X, P140X, G141X, I142X, R143X, Y144X, Q145X, Y146X, N147X, V148X, L149X, T200V, Q207A, R211K, V245Q, L283I, I293V, P294T, K331KR, Q334H, K366R, T386V, K390R, T403M, V435A, Q480H, H483Q, L484I, L491S, S519N, K527Q, K530R, A534S, A554S, K558R  
P19 P19 Unknown Unknown   V35T, E36A, T39D, K43R, S48T, V60I, K122E, D123S, I135M, S162H, K173T, Q174K, D177G, T200A, Q207G, R211K, M230X, G231X, Y232X, E233X, L234X, H235X, P236X, D237X, K238X, W239X, T240X, V241X, Q242X, P243X, I244X, V245X, L246X, P247X, E248X, K249X, D250X, S251X, W252X, T253X, V254X, N255X, D256X, I257X, Q258X, K259X, L260X, V261X, A272P, I274V, K277R, E291D, V292I, I293V, P294T, G333D, R356K, M357I, G359T, K366R, T377L, K390R, E404D, V435A, L452M, V466I, V467I, T470N, D471E, H483Q, L491S, L517V, S519N, K530R, A534S, A554N  
P21 P21 Unknown Unknown  K103N K20R, V35I, E36A, T39E, S48T, K122E, D123G, I135T, T165I, Q207E, R211K, F214L, E224X, P225X, P226X, F227X, L228X, W229X, M230X, G231X, Y232X, E233X, L234X, H235X, P236X, D237X, K238X, W239X, T240X, V241X, Q242X, P243X, I244X, V245X, L246X, P247X, E248X, K249X, D250X, S251X, W252X, T253X, V254X, N255X, D256X, I257X, Q258X, K259X, L260X, A272P, K277R, E291D, V292I, I293V, V317A, G335D, R356K, M357T, G359A, K366R, T377Q, K390R, E404D, V435T, L452K, V466I, S468T, D471E, H483Q, L491S, K527Q, K530R, A534S, A554T  
P22 P22 Unknown Unknown   D121H, K122E, I142V, Q174K, D177E, G196E, T200I, Q207H, R211G, D237N, V245Q, A288S, I293V, I329V, Q334L, K366R, T386I, I393M, T403V, P421PS, T450S, L452S, L491S, K527N, V548I, A554N D185N 
P23 P23 Unknown Unknown  K103N V35T, E36A, T39D, S48T, V60I, K122E, I135T, I142V, R211K, K219X, K220X, H221X, Q222X, K223X, E224X, P225X, P226X, F227X, L228X, W229X, M230X, G231X, Y232X, E233X, L234X, H235X, P236X, D237X, K238X, W239X, T240X, V241X, Q242X, P243X, I244X, V245X, L246X, P247X, E248X, K249X, D250X, S251X, W252X, T253X, V254X, N255X, D256X, I257X, Q258X, K259X, L260X, V261X, G262X, A272P, K277R, T286A, E291D, I293V, P294T, V317A, I329L, G333E, G335N, Q336L, R356K, G359T, K366R, T377Q, V381I, K385R, K390R, E404D, V435A, L452M, V466I, D471E, H483Q, L491S, L517IT, S519N, K527R, E529D, K530R, A534S, A554ST, K558KR  
P24 P24 Unknown Unknown   V118I, I135T, I142M, T200A, E204D, R211K, F214L  
P25 P25 Unknown Unknown   K20R, V35T, T39D, K43R, S48T, K122E, D123G, K173T, T200A, Q207G, R211K, L228X, W229X, M230X, G231X, Y232X, E233X, L234X, H235X, P236X, D237X, K238X, W239X, T240X, V241X, Q242X, P243X, I244X, V245X, L246X, P247X, E248X, K249X, D250X, S251X, W252X, T253X, V254X, N255X, D256X, I257X, Q258X, K259X, L260X, V261X, G262X, A272P, K277R, T286A, E291D, V292I, I293V, Q334H, G335D, R356K, G359A, K366R, T369X, Q373H, I375IV, T377Q, K390R, T403A, E404D, V435A, D460N, S468T, H483Y, K512Q, S519N  
P26 P26 Unknown Unknown   G15X, M16X, D17X, G18X, P19X, K20X, V21X, K22X, Q23X, W24X, P25X, L26X, T27X, E28X, E29X, K30X, I31X, K32X, A33X, L34X, V35X, E36X, I37X, C38X, T39X, E40X, M41X, E42X, K43X, E44X, G45X, K46X, I47X, S48X, K49X, I50X, G51X, P52X, E53X, N54X, P55X, Y56X, N57X, T58X, P59X, V60X, F61X, A62X, I63X, K64X, K65X, K66X, D67X, S68X, T69X, K70X, W71X, R72X, K73X, L74X, V75X, D76X, F77X, R78X, E79X, L80X, N81X, K82X, R83X, T84X, Q85X, D86X, F87X, W88X, E89X, V90X, Q91X, L92X, G93X, I94X, P95X, H96X, P97X, A98X, G99X, L100X, K101X, K102X, K103X, K104X, S105X, V106X, T107X, V108X, L109X, D110X, V111X, G112X, D113X, A114X, Y115X, F116X, S117X, V118X, P119X, L120X, D121X, K122X, D123X, F124X, R125X, K126X, Y127X, T128X, A129X, F130X, T131X, I132X, P133X, S134X, I135X, N136X, N137X, E138X, T139X, P140X, G141X, I142X, R143X, Y144X, Q145X, Y146X, N147X, V148X, L149X, P150X, Q151X, G152X, W153X, K154X, G155X, S156X, P157X, A158X, I159X, F160X, Q161X, S162X, S163X, M164X, T165X, K166X, I167X, L168X, E169X, P170X, F171X, R172X, K173X, Q174X, N175X, P176X, D177X, I178X, V179X, I180X, Y181X, Q182X, Y183X, M184X, D185X, D186X, L187X, Y188X, V189X, G190X, S191X, D192X, L193X, E194X, I195X, G196X, Q197X, H198X, R199X, T200X, K201X, I202X, E203X, E204X, L205X, R206X, Q207X, H208X, L209X, L210X, R211X, W212X, G213X, F214X, T215X, T216X, P217X, D218X, K219X, K220X, H221X, Q222X, K223X, E224X, P225X, P226X, F227X, L228X, W229X, M230X, G231X, Y232X, E233X, L234X, H235X, P236X, D237X, K238X, W239X, T240X, V241X, Q242X, P243X, I244X, V245X, L246X, P247X, E248X, K249X, D250X, S251X, W252X, T253X, V254X, N255X, D256X, I257X, Q258X, K259X, L260X, V261X, G262X, K263X, L264X, N265X, W266X, A267X, S268X, Q269X, I270X, Y271X, A272X, G273X, I274X, K275X, V276X, K277X, Q278X, L279X, C280X, K281X, L282X, L283X, R284X, G285X, T286X, K287X, A288X, L289X, T290X, E291X, V292X, I293X, P294X, L295X, T296X, E297X, E298X, A299X, E300X, L301X, E302X, L303X, A304X, E305X, N306X, R307X, E308X, I309X, L310X, K311X, E312X, P313X, V314X, H315X, G316X, V317X, Y318X, Y319X, D320X, P321X, S322X, K323X, D324X, L325X, I326X, A327X, E328X, I329X, Q330X, K331X, Q332X, G333X, Q334X, G335X, Q336X, W337X, T338X, Y339X, Q340X, I341X, Y342X, Q343X, E344X, P345X, F346X, K347X, N348X, L349X, K350X, T351X, G352X, K353X, Y354X, A355X, R356X, M357X, R358X, G359X, A360X, H361X, T362X, N363X, D364X, V365X, K366X, Q367X, L368X, T369X, E370X, A371X, V372X, Q373X, K374X, I375X, A376X, T377X, E378X, S379X, I380X, V381X, I382X, W383X, G384X, K385X, T386X, P387X, K388X, F389X, K390X, L391X, P392X, I393X, Q394X, K395X, E396X, T397X, W398X, E399X, A400X, W401X, W402X, T403X, E404X, Y405X, W406X, Q407X, A408X, T409X, W410X, I411X, P412X, E413X, W414X, E415X, F416X, V417X, N418X, T419X, P420X, P421X, L422X, V423X, K424X, L425X, W426X, Y427X, Q428X, L429X, E430X, V435A, V466S, S468T, D471E, H483Q, L491S, S519N, K530R, A534S, A554R  
P28 P28 Unknown Unknown   V35T, E36A, T39D, S48T, V60I, D123E, D177E, T200A, R211K, L234X, H235X, P236X, D237X, K238X, W239X, T240X, V241X, Q242X, P243X, I244X, V245X, L246X, P247X, E248X, K249X, D250X, S251X, W252X, T253X, V254X, N255X, D256X, I257X, Q258X, K259X, L260X, V261X, G262X, K263X, L264X, N265X, W266X, A267X, S268X, Q269X, I270X, Y271X, A272X, G273X, I274X, K275X, T286A, E291D, V292I, I293V, E297A, V317A, R356K, M357I, G359T, T377L, K390R, E404D, N447S, L452M, V466I, D471E, H483Q, L491P, S519N, K527N, K530R, A534S, A554N  
P29 P29 Unknown Unknown   V35T, E36A, T39D, S48T, V60I, K122E, I135T, D177E, R211K, K219X, K220X, H221X, Q222X, K223X, E224X, P225X, P226X, F227X, L228X, W229X, M230X, G231X, Y232X, E233X, L234X, H235X, P236X, D237X, K238X, W239X, T240X, V241X, Q242X, P243X, I244X, V245X, L246X, P247X, E248X, K249X, D250X, S251X, W252X, T253X, V254X, N255X, D256X, I257X, Q258X, K259X, L260X, V261X, A272P, K277R, T286A, E291D, V292I, I293V, G335D, R356K, G359T, K366R, T377L, K390R, K395R, E404D, L452I, V466S, D471E, H483Q, L491S, S519N, K530KR, A534S, A554K  
P30 P30 Unknown Unknown   V35T, E36A, T39D, S48T, D123S, D177E, R211X, W212X, G213X, F214X, T215X, T216X, P217X, D218X, K219X, K220X, H221X, Q222X, K223X, E224X, P225X, P226X, F227X, L228X, W229X, M230X, G231X, Y232X, E233X, L234X, H235X, P236X, D237X, K238X, W239X, T240X, V241X, Q242X, P243X, I244X, V245X, L246X, P247X, E248X, K249X, D250X, S251X, W252X, T253X, V254X, N255X, D256X, I257X, Q258X, K259X, L260X, V261X, G262X, A272P, K277R, T286A, E291D, V292I, I293V, S322A, G335D, R356K, G359T, K366R, T377M, T386I, K390R, T397A, E404D, L452LI, D460N, V466VI, S468ST, D471DE, H483Y, L491LS, K512KQ, S519N, K527KQ, K530KR, A534AS, A554X  
P31 P31 Unknown Unknown   V35T, T39D, K43R, S48T, V60I, S68G, K122E, D123S, I135T, R211K, F214L, Y232X, E233X, L234X, H235X, P236X, D237X, K238X, W239X, T240X, V241X, Q242X, P243X, I244X, V245X, L246X, P247X, E248X, K249X, D250X, S251X, W252X, T253X, V254X, N255X, D256X, I257X, Q258X, K259X, L260X, V261X, A272P, K281R, T286AV, E291D, V292I, I293V, V317A, Q334QH, G335D, E344ED, R356K, G359T, K366R, A371V, A376T, T377L, V381I, K390R, E404D, V435A, L452M, V466S, V467I, S468P, D471E, H483Q, L491S, S519N, K527KN, K530R, A534S, A554T  
P32 P32 Unknown Unknown   V8I, V35T, E36EA, T39D, K43R, S48T, K122E, D123N, I135T, I142V, K173T, D177E, V179I, T200A, Q207E, R211K, W212X, G213X, F214X, T215X, T216X, P217X, D218X, K219X, K220X, H221X, Q222X, K223X, E224X, P225X, P226X, F227X, L228X, W229X, M230X, G231X, Y232X, E233X, L234X, H235X, P236X, D237X, K238X, W239X, T240X, V241X, Q242X, P243X, I244X, V245X, L246X, P247X, E248X, K249X, D250X, S251X, W252X, T253X, V254X, N255X, D256X, I257X, Q258X, K259X, L260X, A272S, K277R, Q278E, E291D, V292I, I293V, P294PT, L295LM, I329L, G335D, R356K, G359T, V365I, K366R, T377I, K390R, A400T, E404D, V435I, V466I, D471E, H483Q, L491S, S519N, K530R, A534S, A554K  
P33 P33 Unknown Unknown   V8I, V35T, E36A, T39D, K43R, S48T, K122E, I135T, E194G, G196GE, I202V, R211K, F214L, Q222X, K223X, E224X, P225X, P226X, F227X, L228X, W229X, M230X, G231X, Y232X, E233X, L234X, H235X, P236X, D237X, K238X, W239X, T240X, V241X, Q242X, P243X, I244X, V245X, L246X, P247X, E248X, K249X, D250X, S251X, W252X, T253X, V254X, N255X, D256X, I257X, Q258X, K259X, L260X, V261X, A272P, K277R, E291D, V292I, I293V, V317A, G335D, R356K, G359T, K366R, A376S, T377L, K390R, A400S, E404D, K431Q, V435A, L452M, D471E, H483Q, L491S, S519N, K527R, K530R, A534S, A554S  
P35 P35 Unknown Unknown   V35T, E36A, T39E, K43R, S48T, D121H, K122E, A158S, S162C, K173A, Q174R, D177E, T200A, Q207E, R211K, W229X, M230X, G231X, Y232X, E233X, L234X, H235X, P236X, D237X, K238X, W239X, T240X, V241X, Q242X, P243X, I244X, V245X, L246X, P247X, E248X, K249X, D250X, S251X, W252X, T253X, V254X, N255X, D256X, I257X, Q258X, K259X, L260X, V261X, A272P, T286A, E291D, V292I, I329L, G335D, R356K, M357R, G359T, T377I, K390R, A400T, E404D, V417I, V435A, L452M, V466I, S468C, D471E, I482V, H483Q, L491S, A502V, S519N, K530R, A534S, A554N  
P37 P37 Unknown Unknown   V35T, E36A, T39D, K43R, S48T, K122E, D123G, Q174E, Q197K, R211K, G231X, Y232X, E233X, L234X, H235X, P236X, D237X, K238X, W239X, T240X, V241X, Q242X, P243X, I244X, V245X, L246X, P247X, E248X, K249X, D250X, S251X, W252X, T253X, V254X, N255X, D256X, I257X, Q258X, K259X, L260X, V261X, G262X, K263X, L264X, N265X, W266X, A267X, S268X, Q269X, I270X, Y271X, A272X, G273X, I274X, K275X, K277R, T286A, E291D, V292I, I293V, I329L, G335D, R356K, G359S, D364DN, K366R, A376T, T377L, V381I, K390R, A400T, E404D, T419I, V435I, L452M, V466S, D471E, H483Q, L491P, L517I, S519N, K530R, A534S, A554K  
P38 P38 Unknown Unknown   E29EK, V35T, T39D, K43R, S48T, K122E, D123N, I135T, S162C, R211K, G231X, Y232X, E233X, L234X, H235X, P236X, D237X, K238X, W239X, T240X, V241X, Q242X, P243X, I244X, V245X, L246X, P247X, E248X, K249X, D250X, S251X, W252X, T253X, V254X, N255X, D256X, I257X, Q258X, K259X, L260X, V261X, G262X, K263X, L264X, N265X, W266X, A267X, S268X, Q269X, I270X, Y271X, A272X, G273X, I274X, K275X, V276X, K277X, T286A, V292I, I293V, I329L, R356K, M357I, G359T, T377Q, V381I, K390R, E404D, V435A, L452M, V466I, D471E, H483Q, L491S, S519N, K530R, A534S, A554Q  
P39 P39 Unknown Unknown  K103N V35T, E36A, T39D, S48T, V90I, K122E, D123G, I142V, A158S, K173A, R211K, L234X, H235X, P236X, D237X, K238X, W239X, T240X, V241X, Q242X, P243X, I244X, V245X, L246X, P247X, E248X, K249X, D250X, S251X, W252X, T253X, V254X, N255X, D256X, I257X, Q258X, K259X, L260X, V261X, G262X, K263X, L264X, N265X, W266X, A267X, S268X, Q269X, I270X, Y271X, A272X, G273X, I274X, K277R, E291D, V292I, I293V, I326V, I329IL, G335D, R356K, G359T, K366R, T377LM, K390R, K395R, E404D, V435A, L452V, V466I, L469V, D471E, H483Q, L491S, K530R, A534S, A554S  
P40 P40 Unknown Unknown   V35T, E36A, T39D, S48T, E53D, A158S, S162H, K173A, D177E, T200A, E203D, Q207E, G231X, Y232X, E233X, L234X, H235X, P236X, D237X, K238X, W239X, T240X, V241X, Q242X, P243X, I244X, V245X, L246X, P247X, E248X, K249X, D250X, S251X, W252X, T253X, V254X, N255X, D256X, I257X, Q258X, K259X, L260X, A272P, K277R, E291D, K311R, G335D, R356K, G359T, K366R, T377Q, V381I, K390R, A400T, E404D, V435A, A437V, L452M, V466I, S468T, T470S, D471E, Q480K, H483Q, L491S, S515V, S519N, K530R, A534S, A554S  
P41 P41 Unknown Unknown   A272S, K277R, K281R, T286A, E291D, V292I, I293V, G335D, P345Q, A355T, R356K, G359T, A360T, K366R, T377Q, S379C, K390R, K395R, A400T, E404D, V435I, L452M, S468P, D471E, H483Q, L491P, S519N, Q524H, K530R, A534S, A554S  
P42 P42 Unknown Unknown   V35I, R83K, D250E, A272P, K277R, E297K, L310I, V317A, R358K, G359S, A360T, A376T, E399D, A400T, V435I, T450S, L452K, R461K, T470S, K476Q, L491S, S519N, K527N, A554S K275KN 
P43 P43 Unknown Unknown   V35T, E36A, T39D, V60I, D113N, K122E, D123S, I135T, G155X, S156X, P157X, A158X, I159X, F160X, Q161X, S162X, S163X, M164X, T165X, K166X, I167X, L168X, E169X, P170X, F171X, R172X, K173X, Q174X, N175X, P176X, D177X, I178X, V179X, I180X, Y181X, Q182X, Y183X, M184X, D185X, D186X, L187X, Y188X, V189X, G190X, S191X, D192X, L193X, E194X, I195X, G196X, Q197X, H198X, R199X, T200X, K201X, I202X, E203X, E204X, L205X, R206X, Q207X, H208X, L209X, L210X, R211X, W212X, G213X, F214X, T215X, T216X, P217X, D218X, K219X, K220X, H221X, Q222X, K223X, E224X, P225X, P226X, F227X, L228X, W229X, M230X, G231X, Y232X, E233X, L234X, H235X, P236X, D237X, K238X, W239X, T240X, V241X, Q242X, P243X, I244X, V245X, L246X, P247X, E248X, K249X, D250X, S251X, W252X, T253X, V254X, N255X, D256X, I257X, Q258X, K259X, L260X, V261X, G262X, K263X, L264X, N265X, W266X, A267X, S268X, Q269X, I270X, Y271X, A272X, G273X, I274X, K275X, K277R, T286A, E291D, V292I, I293V, P294T, E297A, A304E, G335D, R356K, G359T, K366R, K374Q, T377L, K390R, E404D, V435A, V466I, D471E, H483Q, L491S, S519N, K530R, A534S, A554S  
P44 P44 Unknown Unknown   V35T, E36EA, T39E, S48T, K122E, I135T, S162C, F171Y, K173T, Q174R, D177E, T200A, E203D, Q207E, R211K, G231X, Y232X, E233X, L234X, H235X, P236X, D237X, K238X, W239X, T240X, V241X, Q242X, P243X, I244X, V245X, L246X, P247X, E248X, K249X, D250X, S251X, W252X, T253X, V254X, N255X, D256X, I257X, Q258X, K259X, L260X, V261X, G262X, K263X, L264X, N265X, W266X, A267X, S268X, Q269X, I270X, Y271X, A272X, G273X, I274X, K275X, K277R, T286A, E291D, V292I, I293V, G335D, R356K, G359T, K366R, T377Q, K390R, E404D, K431R, V435A, L452M, S468T, T470N, D471E, H483Q, L484I, L491S, S519N, K530R, A534S, A554N  
P45 P45 Unknown Unknown   A272P, K277R, T286A, E291D, V292I, I293V, E297A, E312D, I329L, G335D, R356K, G359T, T377Q, V381I, K390R, E404N, V435T, L452M, V466I, S468T, D471E, H483Q, S519N, A534S, A554S  
P46 P46 Unknown Unknown M184V K103N, P225H, N348I V35R, T39D, K43R, S48T, A98S, K122E, D123S, I135L, S162C, K173V, Q174K, T200A, Q207E, R211K, L234X, H235X, P236X, D237X, K238X, W239X, T240X, V241X, Q242X, P243X, I244X, V245X, L246X, P247X, E248X, K249X, D250X, S251X, W252X, T253X, V254X, N255X, D256X, I257X, Q258X, K259X, L260X, V261X, G262X, K263X, L264X, N265X, W266X, A267X, S268X, Q269X, I270X, Y271X, A272X, G273X, I274X, K275X, K277R, T286A, E291D, V292I, E297K, A304E, R356K, G359T, K366R, T377Q, K390R, E399G, E404D, V435A, L452M, V466I, S468T, T470N, D471E, H483Q, L491S, Q524H, K527N, K530R, A534S, A554N C38CW 
P49 P49 Unknown Unknown   E6D, V35T, E36A, T39D, S48T, V60I, K122E, D123S, D177E, V245Q, E248D, A272P, V292I, I293V, Q334H, G335D, R356K, M357T, T377L, E404D, P421S, V435A, L452A, T470M, H483Q, L491S, S519N, K530R, A534S, A554N  
P50 P50 Unknown Unknown   K277R, T286A, E291D, V292I, I293V, I309IL, V317VA, A327V, G335D, R356K, G359T, K366R, T377LQ, V381VI, K390R, E404D, V435A, L452M, V466S, D471E, H483Q, L491S, S519N, K527KR, E529D, K530R, A534S, A554S  
P51 P51 Unknown Unknown   V35T, E36A, T39D, K43R, S48T, V60VI, K122E, D123GS, I135T, K173A, V189I, T200A, Q207E, R211K, H235X, P236X, D237X, K238X, W239X, T240X, V241X, Q242X, P243X, I244X, V245X, L246X, P247X, E248X, K249X, D250X, S251X, W252X, T253X, V254X, N255X, D256X, I257X, Q258X, K259X, L260X, V261X, G262X, K263X, L264X, N265X, W266X, A267X, S268X, Q269X, I270X, Y271X, A272X, G273X, I274X, K275X, K277R, T286A, E291D, V292I, I293V, E297A, D320E, D324E, G335D, R356K, G359T, K366R, T377Q, K385R, K390R, E404D, V435I, V466I, D471E, H483Q, L491S, S519N, K530R, A534S, A554N, I556V  
P54 P54 Unknown Unknown D67N, K70R, M184V, T215F, K219Q A98G, K101P, K103N E28A, V35M, T39D, D121H, K122E, I135T, S162C, K173A, D177E, T200A, I202V, Q207E, R211K, E233X, L234X, H235X, P236X, D237X, K238X, W239X, T240X, V241X, Q242X, P243X, I244X, V245X, L246X, P247X, E248X, K249X, D250X, S251X, W252X, T253X, V254X, N255X, D256X, I257X, Q258X, K259X, L260X, V261X, G262X, K263X, L264X, N265X, W266X, A267X, S268X, Q269X, I270X, Y271X, A272X, G273X, I274X, K277R, E291D, V292I, I293V, K311R, I329L, Q334D, G335D, R356K, G359A, K366R, T377L, K390R, E399D, E404D, V435A, L452M, V466S, D471E, H483Q, I505V, Q509L, S519N, Q524E, K530R, A534S, A554R  
P55 P55 Unknown Unknown   A272P, V276I, K277R, L283I, I293V, P294T, E297K, S322T, I329L, G335A, R356K, A376T, T386I, A400T, T403M  
P56 P56 Unknown Unknown   K277R, D324E, K366R, A376T, T386I, K395R, A400T, T403I, K454N, S519N, K527A, A554K  
P57 P57 Unknown Unknown   V35T, E36A, T39D, S48ST, V60I, K104KR, K122E, D123G, R211K, E233X, L234X, H235X, P236X, D237X, K238X, W239X, T240X, V241X, Q242X, P243X, I244X, V245X, L246X, P247X, E248X, K249X, D250X, S251X, W252X, T253X, V254X, N255X, D256X, I257X, Q258X, K259X, L260X, V261X, G262X, K263X, L264X, N265X, W266X, A267X, S268X, Q269X, I270X, Y271X, A272X, G273X, I274X, K275X, V276X, K277X, Q278X, E291D, V292I, I293IV, G335D, R356K, G359T, K366R, T377Q, K390R, K395R, E404D, V435A, L452M, V466S, V467VFI, D471E, L491S, S519N, K527N, K530R, V531I, A534S, A554S  
P58 P58 Unknown Unknown   V35T, E36A, T39D, K43R, S48ST, K122E, D123N, I135T, S162C, K173A, D177E, T200A, Q207E, R211K, H235X, P236X, D237X, K238X, W239X, T240X, V241X, Q242X, P243X, I244X, V245X, L246X, P247X, E248X, K249X, D250X, S251X, W252X, T253X, V254X, N255X, D256X, I257X, Q258X, K259X, L260X, V261X, G262X, K263X, L264X, N265X, W266X, A267X, S268X, Q269X, I270X, Y271X, A272X, G273X, I274X, K275X, V276X, K277X, Q278X, L279X, C280X, K281X, T286A, E291D, V292I, I293V, V317A, D324E, G335D, R356K, G359A, K366R, T377L, V381I, K390R, E404D, V435A, L452M, V466I, S468P, D471E, L491S, S519N, K527N, K530R, A534S, A554S  
P60 P60 Unknown Unknown   V35T, T39D, S48T, V60I, K122E, D123G, I135T, E233X, L234X, H235X, P236X, D237X, K238X, W239X, T240X, V241X, Q242X, P243X, I244X, V245X, L246X, P247X, E248X, K249X, D250X, S251X, W252X, T253X, V254X, N255X, D256X, I257X, Q258X, K259X, L260X, V261X, G262X, K263X, L264X, N265X, W266X, A267X, S268X, Q269X, I270X, Y271X, A272X, G273X, I274X, K275X, K277R, T286A, E291D, V292I, K311R, Q334H, G335D, R356K, G359S, K366R, T377Q, K390R, E404D, V435A, L452M, R461K, V466C, D471E, H483Q, L491P, S519N, K530R, A534S, A554S Y232Y* 
P9 P9 Unknown Unknown   V35T, T39N, S48T, V60I, K104N, K122E, T200A, R211K, K223X, E224X, P225X, P226X, F227X, L228X, W229X, M230X, G231X, Y232X, E233X, L234X, H235X, P236X, D237X, K238X, W239X, T240X, V241X, Q242X, P243X, I244X, V245X, L246X, P247X, E248X, K249X, D250X, S251X, W252X, T253X, V254X, N255X, D256X, I257X, Q258X, K259X, L260X, V261X, A272P, E291D, V292I, I293V, Q334D, G335D, R356K, G359T, V365VI, K366R, T377L, K390R, E404D, V435A, L452M, V466I, T470A, D471E, H483Q, L484LI, L491PS, K527KN, K530R, A534S, A554N, K558R