Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Kinyua (2018)
Title Antiretroviral resistance among HIV-1 patients on first-line therapy attending a comprehensive care clinic in Kenyatta National Hospital, Kenya: a retrospective analysis.
Citation Pan Afr Med J
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 65
NumPts 65
Subtype A, D, C, B, G, CRF10_CD

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
KN10 KN10 NRTI NNRTI  E138A K11T, K20R, V35T, V60I, K122R, K173L, V179I, T200A, I202V, Q207A, F214X  
KN11 KN11 NRTI NNRTI   V35T, T39E, E40D, S48T, V60I, K122E, D123S, I135T, S162T, K173L, Q174K, D177E, V179I, T200A, Q207A, R211S P14R 
KN12 KN12 NRTI NNRTI   V35T, V60I, I135V, K173I, Q174K, D177E, I178M, T200A, R211K, T215X  
KN13 KN13 NRTI NNRTI   V35T, T39A, V60I, D121Y, K122E, A158S, D177E, I178M, T200I, Q207G, L210Y, R211N  
KN14 KN14 NRTI NNRTI T215L  K32Q, V35K, K43N, K49R, V60I, S68G, D123N, I135K, E169D, K173S, Q174K, I178M, V179I, T200A, Q207A, R211S, T216P  
KN15 KN15 NRTI NNRTI T215L  K11T, K20R, V21I, V35T, T39E, K122E, D123N, K154E, I167X, K173S, D177G, Q182X, L187X, T200A, Q207A, R211S, T216P  
KN16 KN16 NRTI NNRTI   V35T, D121H, K122E, K173S, Q174K, D177E, V179I, I202V, Q207A, R211S  
KN17 KN17 NRTI NNRTI K219R  V35T, E36D, V60I, K102R, K103X, D113X, D121H, K122E, D123E, K173L, Q174K, N175Y, D177E, T200A, Q207D, R211N, T215X  
KN18 KN18 NRTI NNRTI   P4H, K11T, K20R, V21I, V35T, V60I, D121Y, K122E, K173L, Q174K, D177E, Q207A, R211S, T215X  
KN20 KN20 NRTI NNRTI V75I, M184V Y181C V35T, T39M, V60I, D121H, K122E, D123E, I132L, I135T, K173S, Q174K, D177E, V179I, T200A, Q207A, R211S, F214X  
KN21 KN21 NRTI NNRTI   V35T, V60I, K173Q, D177E, V179I, T200A, Q207R, R211K, T215X  
KN22 KN22 NRTI NNRTI   E6K, V8I, K20R, V35T, T39I, V60I, K122E, I135T, K173L, Q174K, D177E, T200A, Q207A, R211S, F214X  
KN23 KN23 NRTI NNRTI  K103N V35T, T39M, K49R, V60I, K122E, D123S, E169D, D177E, I178M, Q207G, R211K, T215X  
KN24 KN24 NRTI NNRTI   V35T, T39E, A98S, K122E, D123S, A158S, K173A, Q174K, D177E, Q182X, G190X, T200A, Q207D D192H 
KN26 KN26 NRTI NNRTI   V35T, E36A, T39E, S48T, K122E, D123S, A158S, T165I, K173S, Q174K, D177E, I178M, T200A, Q207E  
KN27 KN27 NRTI NNRTI   K11Q, V35T, T39A, E40D, S48E, S162Y, K173S, Q174K, D177E, V179I  
KN28 KN28 NRTI NNRTI   K11T, K32R, V35T, E40D, V60I, K122E, D123G, D177E, I178M, D186X, T200I, Q207E, R211K  
KN29 KN29 NRTI NNRTI   V35T, T39A, D121H, K122E, D123S, K173L, D177E, V179I, T200A, Q207A, R211S, T216X  
KN30 KN30 NRTI NNRTI   K11T, K20R, V21I, V35T, D121H, K122E, D123N, T165I, K173S, D177E, I178L, V179I, Q207A, R211S, F214X  
KN31 KN31 NRTI NNRTI   K11T, K20R, T27S, V35T, E40D, V60I, D121H, K122E, D123S, K173A, Q174K, D177E, V179I, Q207A, R211S, F214X  
KN33 KN33 NRTI NNRTI   K11T, K20R, V21I, V35T, T39K, K122E, D123S, K173A, Q174K, V179I, I202V, Q207A, R211N  
KN34 KN34 NRTI NNRTI   V35T, V60I, K122E, I135T, K173A, Q174K, D177E, V179I, G196E, Q207A, T216X  
KN35 KN35 NRTI NNRTI L210W, T215F  E6Q, K11Q, T27S, V35T, V60I, K122E, D123S, I135T, K173A, Q174K, D177E, I178M, E194D, T200A, Q207E, R211D, W212R, F214I L209R, G213T, T216S 
KN37 KN37 NRTI NNRTI M184V K103N, E138A V35T, E36A, T39E, E40D, S48T, T69N, K122E, D123S, S162G, K173T, T200A, Q207E, F214L  
KN38 KN38 NRTI NNRTI   S3C, E6D, K32I, V35I, K49R, V60I, K122E, D123S, I135T, I142V, D177E, Q207A, R211S, T216X  
KN39 KN39 NRTI NNRTI D67N, K70R, M184V, K219Q K103N P14Q, V35T, T39E, S48T, E53D, K122E, D123G, I135M, K173R, Q174K, D177E, G196E, T200A, I202V, Q207E  
KN40 KN40 NRTI NNRTI D67N, M184V, T215S, K219Q Y188L P1S, P4S, K20R, V21I, V35T, T39N, S68G, T69N, K82R, K101N, K102M, K122E, D123N, K173S, Q174K, D177E, V179I, I202V, Q207A, R211K K70L, K73Q, D76Y, R78E, E79Q, R83T, T84P, Q85H 
KN41 KN41 NRTI NNRTI M41L, V75A K103N I2V, V35T, K43N, E44D, V60I, V118I, D121H, K122E, T139K, K173S, Q174R, D177E, G196D, T200A, E203K, L205F, Q207E, H208Y, L210X, R211K, T215X  
KN42 KN42 NRTI NNRTI   V21I, V35T, T39M, V60I, K122E, I135T, K173A, Q174K, D177E, V179I, G196E, Q207A, R211S, T216X  
KN44 KN44 NRTI NNRTI  V106I V21I, V35T, T39G, K173S, D177G, V179I, T200K, I202V, Q207A, R211S, T216X  
KN45 KN45 NRTI NNRTI   K11Q, V35T, V60I, D121H, K122E, D123S, I135T, K173L, Q174K, D177E, V179I, T200A, Q207A, R211S  
KN46 KN46 NRTI NNRTI  E138A V8I, K32R, V35T, E40D, K49R, V60I, K122E, D123E, E169D, D177E, I178M, T200I, Q207E, R211K  
KN47 KN47 NRTI NNRTI M41L K103N E28A, V35M, T39A, K43Q, V60I, K101Q, D121H, K122E, I135T, T200I, R206K, Q207E, L210X, R211K  
KN48 KN48 NRTI NNRTI   V35T, K49R, D123E, D177E, I178M, Q207E, R211K  
KN49 KN49 NRTI NNRTI K70R, M184V, K219Q K103N K20R, E28A, V35T, T39A, S48T, V60I, K101T, K122E, I135T, K173L, Q174K, D177E, V179I, T200A, I202V, Q207A, R211S, T215X I50S, G213D 
KN50 KN50 NRTI NNRTI   E6S, V35T, E36D, T39K, K43R, I47L, K122E, D123N, I135T, I142V, S162D, K173S, Q174K, D177E, V179I, T200A, Q207A, R211S, F214X  
KN51 KN51 NRTI NNRTI   K11T, K20R, V35T, T39R, K173S, D177G, V179I, T200K, I202V, Q207A, R211S, T216X  
KN52 KN52 NRTI NNRTI   E6S, D17E, V35T, E36D, T39K, K122E, I135T, I142V, S162A, T165I, K173S, Q174K, D177E, V179I, T200A, I202V, Q207A, R211S, F214X  
KN53 KN53 NRTI NNRTI  E138A K11R, K32R, V35T, E40D, K49R, V60I, K122E, D123E, E169D, D177E, I178M, T200I, Q207E, R211K, T215X  
KN54 KN54 NRTI NNRTI  G190A V35T, K49R, V60I, D121Y, K122E, I135T, D177E, I178M, E194D, Q207E, R211K, T215P, T216P  
KN56 KN56 NRTI NNRTI   V21I, V35T, E36A, T39E, E40D, S48T, K122E, D123S, I135T, S162A, K173S, Q174K, N175H, D177E, V179I, T200A, Q207A, R211S  
KN57 KN57 NRTI NNRTI   V35A, T39A, V60I, K102Q, K122E, D123N, I135T, K173L, Q174K, D177E, V179I, T200A, Q207A, R211S, T215P  
KN58 KN58 NRTI NNRTI   T7P, V35T, E40D, V60I, K122E, D123G, I135T, S162Y, K173S, Q174K, V179I, T200A, Q207A, L210X, R211N, F214X  
KN59 KN59 NRTI NNRTI   E6K, K11Q, V35T, V60I, K122E, D123N, I135T, I142V, S162Y, K173S, Q174K, V179I, T200A, Q207A, R211N  
KN60 KN60 NRTI NNRTI   P1L, I5T, V35T, E36A, T39E, E40D, S48T, K102R, K104X, P119X, K122E, D123N, S162A, K173A, D177E, D186E, L187*, T200A  
KN61 KN61 NRTI NNRTI   V35T, E40D, V60I, D121Y, K122E, D123E, K173A, Q174K, D177E, I178L, V179I, Q207A, R211S, T216X  
KN62 KN62 NRTI NNRTI   V8I, V35T, T39S, V60I, S68N, K122E, D123E, I135T, D177E, T200A, Q207E, R211K  
KN64 KN64 NRTI NNRTI   I5V, P9X, V10X, L12I, P14A, V35T, K49R, V60I, D121H, K122E, D123E, D177E, I178M, Q207E, R211K  
KN66 KN66 NRTI NNRTI  E138A V35T, T39L, V60I, K122E, I135T, I142V, T165I, K173S, Q174K, D177E, V179I, T200A, Q207E, R211S, F214L  
KN67 KN67 NRTI NNRTI  K103N V35T, K49R, V60I, D121Y, K122E, D177E, I178M, Q207E, R211K, T215X  
KN68 KN68 NRTI NNRTI T215S E138A K20R, V35T, T39K, V60I, S68G, K122E, D123N, I135T, T165I, K173L, Q174K, V179I, Q207A, R211S  
KN69 KN69 NRTI NNRTI  E138A K20R, V35T, T39K, V60I, S68G, K122E, D123N, I135T, T165I, K173L, Q174K, V179I, Q207A, R211S, F214X  
KN7 KN7 NRTI NNRTI   K11T, V35T, K122E, D123G, I135T, K173S, D177E, V179I, Q207A, R211S  
KN70 KN70 NRTI NNRTI  K103N V35T, K49R, V60I, D121Y, K122E, E169D, D177E, I178M, Q207E, R211K  
KN71 KN71 NRTI NNRTI T215S E138A V35T, T39L, V60I, K122E, I135T, I142V, T165I, K173S, Q174K, D177E, V179I, T200A, Q207E, R211S, F214L  
KN72 KN72 NRTI NNRTI   D121H, K122E, I135K, I142V, D177E, Q207E, R211K, F214L T128A, Q161L 
KN74 KN74 NRTI NNRTI   V35T, T39A, E40D, K49R, V60I, K122E, D123S, I135T, I142V, E169D, D177E, T200A, E204K, Q207E, T215P, T216P  
KN75 KN75 NRTI NNRTI   P4H, K11E, V35T, E40D, V60I, D121H, K122E, D123S, I135T, T165I, K173S, Q174K, D177E, V179I, T200A, Q207A, R211S L209V 
KN76 KN76 NRTI NNRTI   K32R, V35T, V60I, D121Y, K122E, I135L, K173S, Q174K, D177E, T200I, Q207E, R211K, T215X  
KN77 KN77 NRTI NNRTI   V35T, V60I, K122E, D123K, F124L, I135T, K173S, Q174K, D177E, T200A, Q207A, R211S, F214L  
KN78 KN78 NRTI NNRTI M41L, M184V K103N, E138G V35T, V60I, K102Q, D121Y, K122E, I135L, K173A, Q174K, D177E, I178M, V179I, T200A, Q207A, L210X, T215X  
KN79 KN79 NRTI NNRTI   K11T, K20R, V35T, T39K, E40D, V60I, K122E, D123S, K173A, V179I, T200A, I202V, Q207A, R211S  
KN8 KN8 NRTI NNRTI K70T V179D V35T, V60I, D123E, S162A, T165I, E169D, D177E, I178M, Q197E, T200A, Q207A, R211K, T215P, T216P P14R 
KN80 KN80 NRTI NNRTI   V35T, E36A, T39E, E40D, K122E, D123N, A158S, K173A, Q174R, D177E, T200A, Q207E, T215P, T216P L209V 
KN9 KN9 NRTI NNRTI   V35T, V60I, K122E, I135T, K173S, Q174K, D177E, V179I, T200A, R206K, Q207A