Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Banin (2019)
Title Near full genome characterization of HIV-1 unique recombinant forms in Cameroon reveals dominant CRF02_AG and F2 recombination patterns.
Citation J Int AIDS Soc
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 18
NumPts 18
Subtype CRF02_AG, F, A

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
BDHS24_2 BDHS24_2 None None T69V_L, M184V V108I, Y181C, H221Y K11Q, K20R, E29D, V35T, T39A, E44D, S68T, K70*, D123E, I135L, F171Y, K173A, Q174K, D177E, I178L, T200A, Q207E, R211K, P243A, V245Q, E248D, D250S, A272P, K275R, Q278H, K281R, L283I, T286A, E291D, I293V, L295M, E297A, I329V, Q334H, G335D, F346H, R356K, M357R, R358K, G359S, A371V, K385R, T386V, K390R, A400T, K431T, R448K, V458I, V467I, D471E, H483Q, L491S, Q509H, L517I, S519N, K527Q, K530R, A534S, A554S N54Y, F61Y, A62C, I63H, K65D, K66S, D67R, D76H 
BDHS33 BDHS33 Unknown Unknown  V106VI K20KR, V35T, E36ED, T39TA, E40ED, E44ED, K122KE, D123E, S162C, K173S, Q174K, D177E, Q207E, R211A, P243A, V245Q, D250N, A272P, K275R, V276I, Q278H, T286A, E291D, I293V, E297A, G335D, F346H, R356K, M357R, G359S, A371V, A376S, S379G, T386V, K390R, A400T, K431T, E432D, V458I, R461K, S468T, D471E, L491S, V496I, Q509H, K512R, S519N, K527Q, K530R, A534S  
LB016_1 LB016_1 None None   E6K, K11N, V35T, T39L, K122E, D123G, S162A, K173T, Q174K, D177E, Q197K, T200A, I202V, Q207D, R211K, F214L, V245Q, A272P, K281R, T286A, I293V, P294T, K311R, S322T, L325I, I326V, Q334P, G335D, R356K, M357K, G359S, A360T, K366R, T369V, A371V, V372I, I375V, K390R, A400T, E413D, E432D, S468P, D471E, Q480H, L491S, K512R, S519N, Q520L, Q524K, K527E, E529D, A534S, A554N  
LB069_1 LB069_1 None None   V35T, T39L, S48T, E169D, K173A, Q174K, D177E, T200A, E203D, Q207D, R211K, P243A, V245Q, E248D, D250S, A272P, K275R, Q278N, L283I, T286A, E291D, I293V, E297P, Q334H, G335D, F346H, R356K, M357R, R358K, G359S, I375V, T386I, K390R, A400T, Y405H, K431T, V435L, R448K, L452I, S468P, D471E, Q480H, H483Q, L491S, Q509H, L517I, S519N, K527Q, K530R, A534S, A554T, K558E  
LB082_1 LB082_1 None None   E6D, K11T, V35T, E36A, T39K, K43E, E53D, S162Y, K173S, Q174K, D177E, V179I, Q207A, F214L, V245Q, T286A, E291D, V292I, I293V, E312D, I326V, G335D, M357K, G359S, K366R, T369V, A371V, I375V, A376V, T377M, A400T, W410C, E432D, V435M, A446S, N447S, L469F, D471E, Q480H, H483L, L491S, Q509H, S519N, K527Q, K530R, A534S, A554N  
LB089_1 LB089_1 None None   V35T, V60I, D121H, K122E, D123S, A158S, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, V245K, V254G, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, R356K, M357R, G359S, T369V, A371V, I375V, T377V, K390R, T403Q, E432D, V435L, L452T, R461K, L469I, T470A, D471E, Q480H, H483Y, L491S, K512R, S519N, Q524K, K527E, E529D, A534S, A554S  
LB095_1 LB095_1 None None   V35T, V60I, D121H, K122E, D123S, T131P, A158S, S162A, K173T, Q174K, D177E, T200A, Q207E, R211K, V245K, T286A, E291D, V292I, I293V, P294T, S322T, I326V, G335D, R356K, M357R, G359S, T369V, A371V, I375V, K390R, T403Q, E432D, V435L, L452T, R461K, L469I, T470A, D471E, Q480H, H483Y, L491S, K512R, S519N, Q524K, K527E, E529D, A534S, A554S  
LB104_1 LB104_1 None None   V35T, T39L, S48T, E169D, K173A, Q174K, D177E, T200A, E203D, Q207D, R211K, P243A, V245Q, E248D, D250S, A272P, K275R, Q278N, L283I, T286A, E291D, I293V, E297P, Q334H, G335D, F346H, R356K, M357R, R358K, G359S, I375V, T386I, K390R, A400T, Y405H, K431T, V435L, R448K, L452I, S468P, D471E, Q480H, H483Q, L491S, Q509H, L517I, S519N, Q520L, K528R, E529N, A534S, A554N L525A_N, I526T 
MDC131_3 MDC131_3 None None   K20R, V35T, T39A, E40D, D123E, S162C, K173S, Q174K, D177E, Q207E, R211A, P243A, V245Q, D250N, A272P, K275R, V276I, Q278H, T286A, E291D, I293V, E297A, G335D, F346H, R356K, M357R, G359S, A371V, A376S, S379G, T386V, K390R, A400T, K431T, E432D, V458I, R461K, S468T, D471E, L491S, V496I, Q509H, K512R, S519N, K527Q, K530R, A534S  
MDC179_2 MDC179_2 None None   E6K, K11N, V35T, T39L, K122E, D123G, S162A, K173T, Q174K, D177E, Q197K, T200A, I202V, Q207D, R211K, F214L, V245Q, A272P, K281R, T286A, I293V, P294T, K311R, S322T, L325I, I326V, Q334P, G335D, R356K, M357K, G359S, A360T, K366R, T369V, A371V, V372I, I375V, K390R, A400T, E413D, E432D, S468P, D471E, Q480H, L491S, K512R, S519N, Q520L, Q524K, K527E, E529D, A534S, A554N  
NYU1122_1 NYU1122_1 None None   E6K, K11N, V35T, T39L, K122E, D123G, S162A, K173T, Q174K, D177E, Q197K, T200A, I202V, Q207D, R211K, F214L, V245Q, A272P, K281R, T286A, I293V, P294T, K311R, S322T, L325I, I326V, Q334P, G335D, R356K, M357K, G359S, A360T, K366R, T369V, A371V, V372I, I375V, K390R, A400T, E413D, E432D, S468P, D471E, Q480H, L491S, K512R, S519N, Q520L, Q524K, K527E, E529D, A534S, A554N  
NYU119_3 NYU119_3 Unknown Unknown   K20R, V35T, T39A, E40D, D123E, S162C, K173S, Q174K, D177E, Q207E, R211A, P243A, V245Q, D250N, A272P, K275R, V276I, Q278H, T286A, E291D, I293V, E297A, G335D, F346H, R356K, M357R, G359S, A371V, A376S, S379G, T386V, K390R, A400T, K431T, E432D, V458I, R461K, S468T, D471E, L491S, V496I, Q509H, K512R, S519N, K527Q, K530R, A534S  
NYU124_2 NYU124_2 None None   K20R, V35T, T39A, E40D, D123E, S162C, K173S, Q174K, D177E, Q207E, R211A, P243A, V245Q, D250N, A272P, K275R, V276I, Q278H, T286A, E291D, I293V, E297A, G335D, F346H, R356K, M357R, G359S, A371V, A376S, S379G, T386V, K390R, A400T, K431T, E432D, V458I, R461K, S468T, D471E, L491S, V496I, Q509H, K512R, S519N, K527Q, K530R, A534S  
NYU129_5 NYU129_5 None None   V35T, E36D, T39L, K122E, I135V, Q145C, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, V245Q, E248D, T286A, E291D, V292I, I293V, P294T, E312D, S322A, I326V, G335D, R356K, M357R, G359T, A360T, A371V, I375V, T377M, K390R, T403L, V435I, D471E, Q480H, L491S, K512R, S519N, Q520L, Q524K, K527E, E529D, A534S, A554N, K558R, V559I  
NYU1999 NYU1999 None None   E6K, K11N, V35T, T39L, K104X, K122E, D123G, S162A, K173T, Q174K, D177E, Q197K, T200A, I202V, Q207D, R211K, F214L, V245Q, A272P, K281R, T286A, I293V, P294T, K311R, S322T, L325I, I326V, Q334P, G335D, R356K, M357K, G359S, A360T, K366R, T369V, A371V, V372I, I375V, K390R, A400T, E413D, E432D, S468P, D471E, Q480H, L491S, K512R, S519N, Q520L, Q524K, K527E, E529D, A534S, A554N  
NYU2140_1 NYU2140_1 None None   E6K, K11N, V35T, T39L, K104X, K122E, D123G, S162A, K173T, Q174K, D177E, Q197K, T200A, I202V, Q207D, R211K, F214L, V245Q, A272P, K281R, T286A, I293V, P294T, K311R, S322T, L325I, I326V, Q334P, G335D, R356K, M357K, G359S, A360T, K366R, T369V, A371V, V372I, I375V, K390R, A400T, E413D, E432D, S468P, D471E, Q480H, L491S, K512R, S519N, Q520L, Q524K, K527E, E529D, A534S, A554N  
NYU6541_6_bulk NYU6541_6_bulk None None   K20R, V35T, S162A, K173A, Q174K, D177E, Q207E, R211K, V245L, A272P, K275R, Q278H, T286A, E291D, V292I, I293V, P294T, E297A, L303M, R307K, Q334H, G335D, F346H, M357R, G359S, A371V, I375V, S379G, T386V, K390R, A400T, K431A, E432D, V458I, V466I, D471E, L491S, Q509H, S519N, K527R, A534S, A554N  
NYU6556_3 NYU6556_3 None None   V35T, T39K, K49R, K122A, S162A, K173T, Q174N, D177E, T200A, E204K, Q207E, R211K, V245Q, E248D, K281R, T286A, A288T, E291D, V292I, I293V, S322A, G335D, R356K, M357R, G359S, A360T, T369A, K374R, K390R, T403M, V435T, R461K, D471E, Q480H, H483Y, L491S, K512R, E514K, S519N, Q520K, I521M, Q524K, E529D, A534S, A554S G273E, E399V