Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Lapovok (2017)
Title HIV Type 1 Integrase Natural Polymorphisms in Viral Variants Circulating in FSU Countries.
Citation Curr HIV Res
SelectedGene PR
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 93
NumPts 92
Subtype A, B, CRF63_02A1, CRF02_AG, CRF03_AB, C, CRF06_cpx

 

Clinical PR Isolates


SubjectIsolatePIsWksPIMajorPIMinorCommonUnusual
01UADN121 01UADN121 None    I13V, K14R, G16E, E35D, M36I, R41K, H69K, L89M, I93L  
01UADN139 01UADN139 None    I13V, K14R, E35D, M36I, N37D, R41K, H69K, L89M  
01UAKV167 01UAKV167 None    I64V  
01UAKV252 01UAKV252 None    N37H, R41K, V77I, I93L  
01UAKV254 01UAKV254 None    I13V, K14R, E35D, M36I, N37D, R41K, H69K, L89M, I93L  
01UAKV259 01UAKV259 None    N37H, R41K, V77I, I93L  
01UAOD10 01UAOD10 None    I13V, E35D, M36I, R41K, H69K, L89M, I93L  
01UAOD35 01UAOD35 None    E35D, M36I, N37D, R41K, H69K, L89M  
01UAOD89 01UAOD89 None    I13V, E35D, M36I, R41K, Q61E, I64M, H69K, L89M, I93L  
01UAPol293 01UAPol293 None    K14R, E35D, M36I, R41K, H69K, L89M, I93L  
01UAPol294 01UAPol294 None    P1L, K14R, E35D, M36I, R41K, H69K, L89M, I93L  
01UAPol303 01UAPol303 None    K14R, E35D, M36I, R41K, H69K, L89M, I93L  
02UZ0659 02UZ0659 None    I13V, K14R, E35D, M36I, R41K, H69K, V77I, L89M, I93L  
02UZ0663 02UZ0663 None   M46V I13V, K14R, E35D, M36I, R41K, H69K, L89M, I93L  
02UZ0667 02UZ0667 None    I13V, K14R, E35D, M36I, R41K, H69K, V77I, L89M, I93L  
02UZ0672 02UZ0672 None    I13V, K14R, E35D, M36I, R41K, H69K, V77I, L89M, I93L  
02UZ0683 02UZ0683 None    I13V, K14R, G16E, K20I, E35D, M36I, N37D, R41K, H69K, L89M  
02UZ652 02UZ652 None    I13V, K14R, E35D, M36I, R41K, H69K, V77I, L89M, I93L  
02UZ693 02UZ693 None    I13V, K14R, G16E, K20I, E35D, M36I, N37D, R41K, H69K, L89M  
02UZ694 02UZ694 None    I13V, K14R, E35D, M36I, R41K, H69K, V77I, L89M, I93L W42G 
02UZ698 02UZ698 None    I13V, E35D, M36I, R41K, H69K, V77I, L89M, I93L  
02UZ710 02UZ710 None    I13V, K14R, G16E, K20I, E35D, M36I, N37D, R41K, H69K, L89M  
02UZ740 02UZ740 None    I13V, K14R, E35D, M36I, R41K, H69K, V77I, L89M, I93L  
03GEMZ019 03GEMZ019 None    T12A, K14R, L33V, N37Y, I62V, L63P, I64L, H69Q  
03GEMZ037 03GEMZ037 None    I13V, K14R, E35D, M36I, N37D, R41K, Q61E, H69K, L89M  
03RU20-06-13 03RU20-06-13 PI    I13V, K14KR, E35D, M36I, R41K, H69K, V77I, L89M, I93L  
04RU001 04RU001 None    I13V, K14R, G17E, K20I, E35D, M36I, R41K, L63H, H69K, L89M, F99L  
04RU139095 04RU139095 None    E35ED, N37C, Q61E, I62V, L63T, E65D  
09RU4457 09RU4457 PI    E35D, M36I, R57K, L63P, I64V, I72V, I93L  
09RU4829 09RU4829 Unknown    I13V, K14R, G16E, K20I, E35D, M36I, N37D, R41K, I64M, H69K, L89M  
10RU5983 10RU5983 Unknown    I13V, K14R, G16E, K20I, E35D, M36I, N37D, R41K, I64M, H69K, L89M  
10RU6366 10RU6366 Unknown    L10V, I13V, K14R, G16E, K20I, E35D, M36I, N37D, R41K, I64M, H69K, L89M  
10RU6509 10RU6509 Unknown    I13A, K14R, G16E, K20I, E35D, M36I, N37D, R41K, H69K, L89M  
10RU6617 10RU6617 Unknown    K14R, E35D, M36I, R41K, H69K, L89M, I93L  
10RU6629 10RU6629 PI    L10I, I15V, N37S, R41K, W42Y, L63A, I93L  
10RU6637 10RU6637 Unknown    I13V, K14R, G16E, K20I, E35D, M36I, N37D, R41K, I64M, C67Y, H69K, L89M  
10RU6649 10RU6649 Unknown    I13V, K14R, G16E, K20I, E35D, M36I, N37D, R41K, I64M, H69K, L89M  
10RU6792 10RU6792 Unknown    I13V, G16E, E35D, M36I, R41K, L63S, H69K, V77I, L89M, I93L  
10RU6829 10RU6829 Unknown    I13V, K14R, G16E, K20I, E35D, M36I, N37D, R41K, I64M, C67S, H69K, L89M  
11RU18n 11RU18n Unknown    I13V, K14R, G16E, K20I, E35D, M36I, N37D, R41K, I64M, C67Y, H69K, L89M  
11RU21n 11RU21n PI    K14R, L33V, E35D, N37Y, I62V, L63P, H69Q  
11RU6900 11RU6900 Unknown    I13V, K14R, G16E, K20I, E35D, M36I, N37D, R41K, H69K, K70R, L89M  
11RU6939 11RU6939 Unknown    L10V, I13V, G16E, K20R, E35D, M36I, N37D, P39S, R41K, H69K, L89M  
11RU6950 11RU6950 Unknown    T12A, I13V, K14R, E35D, M36I, N37D, R41K, H69K, L89M, I93L  
1280 1280 None    L10V, G16E, N37S, R41K, L63T, E65D  
129005 129005 None    K14R, L63P, V77I, P79PS, I93L  
12RU15r 12RU15r Unknown    I13V, K14R, G16E, K20I, E35D, M36I, N37D, R41K, H69K, L89I  
139089 139089 None    L10I, T12S, E35D, N37E, L63P, C67H, A71T, I72K, I93L  
97BL006 97BL006 None  D30DN, V82VA G73GS I13V, K14R, E35D, M36I, R41K, I64V, G68GE, H69K, L89M, I93L G51GR, G86GR 
98GEMZ001 98GEMZ001 None    T12S, V77I  
98GEMZ004 98GEMZ004 None    T12S, I15V, L19I, M36I, N37S, R41K, L63V, H69K, T74S, L89M, I93L  
98GEMZ006 98GEMZ006 None    I13V, K14R, I15V, L63P  
DE00208RU002 DE00208RU002 PI    I13V, K14R, G16E, K20L, E35D, M36I, N37D, R41K, L63S, H69K, K70R, L89M  
DEMA108RU003 DEMA108RU003 None    G16A, E35D, M36I, R41K, Q61E, H69K, L89M, I93L  
DEMA108RU004 DEMA108RU004 None    I13V, M36I, R41K, H69K, L89I, I93L  
DEMA111UA002 DEMA111UA002 PI    K14R, E35D, M36I, R41K, C67Y, H69K, L89M, I93L  
DEMA111UA008 DEMA111UA008 PI    K14R, E35D, M36I, R41K, K43E, L63P, H69K, L89M  
DEMA111UA009 DEMA111UA009 PI    I13V, K20R, E35D, M36I, N37D, R41K, D60E, H69K, K70R, L89M  
DEMA112UA014 DEMA112UA014 PI    I13V, K14R, G16E, E35D, M36I, R41K, H69K, I72V, L89M  
DEMA112UA024 DEMA112UA024 PI    L10I, I13V, K14R, G16E, E35D, M36I, R41K, L63V, H69K, L89M  
DEMA112UA030 DEMA112UA030 PI    K14R, E35D, M36I, N37D, R41K, H69K, L89M, I93L  
DEMA112UA034 DEMA112UA034 PI    L10I, K20R, E35D, M36I, N37D, R41K, L63P, I64L, H69K, K70R, L89M, I93L  
DEMA112UA036 DEMA112UA036 PI    I13V, K14R, E35D, M36I, R41K, L63P, H69K, L89M, I93L  
DEMA112UA042 DEMA112UA042 PI    E35D, M36I, N37E, R41K, H69K, L89M  
DEURF08RU001 DEURF08RU001 None    I13V, K14R, G16E, K20L, E35D, M36I, N37D, R41K, L63S, G68E, H69K, L89M  
Irkutsk_5 Irkutsk_5 None    I13V, I15V, E35D, M36I, R41K, L63P, H69K, V77I, L89M, I93L  
KAL153 KAL153 None    Q7R, I13V, K14R, E35D, M36I, R41K, H69K, L89M, I93L  
KZKAR300435 02K300435 None    I13V, K14R, E35D, M36I, R41K, H69K, L89M, I93L  
KZPAV300480 02P300480 None    I13V, K14R, G16E, E35D, M36I, R41K, H69K, L89M, I93L  
KZPAV300497 02P300497 None    I13V, E35D, M36I, R41K, H69K, V77I, L89M, I93L  
KZPAV300502 02P300502 None    I13V, K14R, G16E, E35D, M36I, R41K, H69K, L89M, I93L  
KZYUZ300413 02Y300413 None    I13V, K14R, E35D, M36I, R41K, H69K, V77I, L89M, I93L  
KZYUZ300425 02Y300425 None    I13V, K14R, E35D, M36I, R41K, H69K, V77I, L89M, I93L  
MSK_SK_005 MSK_SK_005 None    I13V, K14R, G16E, K20I, E35D, M36I, N37D, R41K, H69K, L89M, Q92R  
MSK_SK_006 MSK_SK_006 None    I13V, I15V, E35D, M36I, R41K, L63P, H69K, V77I, L89M, I93L  
MSK_SK_007 MSK_SK_006-1 None    I13V, I15V, E35D, M36I, R41K, L63P, H69K, V77I, L89M, I93L  
  MSK_SK_007 None    G16E, E35D, M36I, R41K, Q61E, H69K, L89M, I93L  
PokA79Ru PokA79Ru PI    E35D, M36I, R41K, H69K, L89M  
PV85 PV85 PI    L10V, I13V, G16E, E35D, M36I, R41K, H69K, L89M  
RU00051 RU00051 Unknown    I13V, E35D, M36I, R41K, H69K, T74A, L89M, I93L  
RU01029 RU01029 None    I13V, K14R, E35D, M36I, R41K, H69K, T74A, V77I, L89M, Q92L V75A 
RU98001 RU98001 None    I13V, K14R, E35D, M36I, R41K, H69K, L89M, I93L  
RUA001 RUA001 None    I13V, L19I, E35D, M36I, R41K, L63P, H69K, V77I, L89M, I93L  
RUA007 RUA007 None    G16E, E35D, M36I, R41K, Q61E, H69K, L89M, I93L  
RU_560_1125 RU_560_1125 None    I13V, K14R, E35D, M36I, R41K, H69K, K70Q, V77I, L89M, I93L  
RU_8141 RU_8141 Unknown    I13V, K14R, G16E, K20I, E35D, M36I, N37D, R41K, I64M, C67H, H69K, L89M  
RU_8169 RU_8169 Unknown    I13V, K14R, G16E, K20I, E35D, M36I, N37D, R41K, K43R, L63H, I64M, H69K, L89M  
RU_8501 RU_8501 Unknown    I13V, I15IL, G16E, K20I, E35D, M36I, N37D, R41K, I64M, H69K, K70R, L89M  
RU_915_1016 RU_915_1016 None    K14R, E35D, M36I, R41K, H69K, L89M  
RU_915_1035 RU_915_1035 None    L10I, K14R, E35D, M36I, R41K, L63P, H69K, L89M, I93L  
RU_915_1038 RU_915_1038 None    K14R, G16GE, E35D, M36I, R41K, H69K, V77I, L89M, I93L  
RU_915_1041 RU_915_1041 None    I13V, K14R, I15V, E35D, M36I, R41K, H69K, L89M  
RU_SP_B_049 RU_SP_B_049 None    K14R, E35ED, M36I, R41K, H69K, L89M, I93L