Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Lapovok (2017)
Title HIV Type 1 Integrase Natural Polymorphisms in Viral Variants Circulating in FSU Countries.
Citation Curr HIV Res
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 503
NumPts 502
Subtype A, CRF02_AG, B, CRF63_02A1, G, C, CRF03_AB, CRF20_BG, CRF06_cpx

 

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Page 1   listing Isolate 1 to Isolate 100 from Total 503 Clinical IN Isolates


SubjectIsolateINIsWksINIMajorINIMinorCommonUnusual
01UADN121 01UADN121 None    V32I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255N  
01UADN139 01UADN139 None    D3E, R20K, V31I, I72V, L74I, T112V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, L234I, S255N, S283G  
01UAKV167 01UAKV167 None    E10D, T112I, I113V, T124N, T125A, I203M  
01UAKV252 01UAKV252 None    L74I, L101I, K111T, S119P, T122I  
01UAKV254 01UAKV254 None    D3E, R20K, V31I, I72V, L74I, L101LV, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255N  
01UAKV259 01UAKV259 None    E11D, K111T, V151I  
01UAOD10 01UAOD10 None    D3E, K14R, R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134D, K136Q, D167E, V201I, T218I, L234I, S255N  
01UAOD35 01UAOD35 None    D3E, K7Q, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, L234I, S255N  
01UAOD89 01UAOD89 None    D3E, R20K, L28I, L45Q, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, L234I, S255N  
01UAPol293 01UAPol293 None    D3E, E11D, R20K, A21T, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, K211R, T218I, L234I, P238S, S255N  
01UAPol294 01UAPol294 None    D3E, R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255N  
01UAPol303 01UAPol303 None    D3E, R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, W243X, S255N  
02UZ0659 02UZ0659 None    D3E, R20K, V31I, I72V, L74M, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255N, D286E  
02UZ0663 02UZ0663 None    D3E, R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255N  
02UZ0667 02UZ0667 None    D3E, R20K, V31I, I72V, L74M, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255N  
02UZ0672 02UZ0672 None    D3E, R20K, V31I, E48K, I72V, L74M, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, H183P, V201I, T218I, L234I, S255N Y194S 
02UZ0683 02UZ0683 None    E11D, K14R, V31I, M50T, L101I, T112V, T125A, G134N, I135V, K136T, V201I, T206S, L234I, R269K, S283G, D288N  
02UZ652 02UZ652 None   H51Y D3E, R20K, V31I, E48K, I72V, L74M, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255N  
02UZ693 02UZ693 None    E11D, K14R, V31I, M50T, L101I, T112V, T125A, G134N, I135V, K136T, E170G, V201I, T206S, L234I, R269K, S283G, D288N  
02UZ694 02UZ694 None    D3E, R20K, V31I, E48K, L74M, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255N  
02UZ698 02UZ698 None    D3E, E11D, R20K, V31I, E48K, I72V, L74M, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255N  
02UZ710 02UZ710 None    E11D, K14R, V31I, M50T, L68V, L101I, T112V, T125A, G134N, I135V, K136T, V201I, T206S, L234I, R269K, S283G, D288N  
02UZ740 02UZ740 None    D3E, R20K, V31I, I72V, L74M, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, I161T, D167E, V201I, T218I, L234I, S255N  
03GEMZ019 03GEMZ019 None   E157Q S24G, L101V, K111R, T112I, T125A, K160Q, S230N, L234I, A265V, D279G  
03GEMZ037 03GEMZ037 None    D3E, R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134D, K136Q, D167E, V201I, T218I, L234I, S255N  
04RU001 04RU001 None    S17N, S24N, V31I, L63I, L74I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218I, L234I, D256E, S283G  
04RU139095 04RU139095 None    E11D, I60M, K111T, S119G, T122I, V150VI, G272GE, D278N W243W*, D253DN 
09RU4829 09RU4829 Unknown    E11D, K14R, S24N, V31I, D41E, M50I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, V201I, T218I, L234I, S255N  
10 IN_10 None    E11D, S24N, V31I, M50I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, V201I, T218I, L234I, S255N  
10RU5983 10RU5983 Unknown    E11D, K14R, S24N, V31I, M50I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, V201I, T218I, L234I, S255N  
10RU6366 10RU6366 Unknown    E11D, S24N, V31I, M50I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, V201I, L234I, S255N  
10RU6509 10RU6509 Unknown    E11D, V31I, M50T, I72T, L74I, L101I, T112V, S119P, T122I, T125A, G134N, I135V, K136T, V201I, T206S, L234I, R269K, S283G, D288N  
10RU6617 10RU6617 Unknown    D3E, R20K, V31I, I72V, L74I, I84M, T112V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255N, V259I  
10RU6637 10RU6637 Unknown    E11D, K14R, S24N, V31I, M50I, K111R, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, V201I, L234I, S255N  
10RU6649 10RU6649 Unknown    E11D, K14R, S24N, V31I, M50I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, V201I, T218I, L234I, S255N  
10RU6792 10RU6792 Unknown    D3E, R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124N, T125A, G134N, K136Q, D167E, V201I, L234I, S255N  
10RU6829 10RU6829 Unknown    E11D, K14R, S24N, V31I, M50I, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, A169T, V201I, T218I, L234I, S255N  
11 IN_11 None    E11D, S24N, V31I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, V201I, T218I, L234I, S255N  
11RU18n 11RU18n Unknown    E11D, K14R, S24N, V31I, M50I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, V201I, T218I, L234I, S255N  
11RU6900 11RU6900 Unknown    E11D, K14R, S24N, V31I, L101I, T112V, T125A, G134N, I135V, K136T, V201I, T206S, L234I, R269K, S283G, D288N  
11RU6939 11RU6939 Unknown    K14R, A21T, V31I, M50MT, Y99F, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, R269K, S283G, D288N  
11RU6950 11RU6950 Unknown    D3E, R20K, V31I, I72V, L74I, T112V, S119P, T124N, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255N  
12 IN_12 None    E11D, S24N, V31I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, V201I, T218I, L234I, S255N D6Y 
1280 1280 None    E10D, T124N, S255T, D256E  
129005 129005 None    S24SG, M50MI, L101I, T124N, T125AV, V165I, H171HQ, D232E, A265V  
12RU15r 12RU15r Unknown    E11D, K14R, S24N, V31I, M50I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, V201I, L234I, S255N  
139089 139089 None    E11D, R20K, V31VI, S39SN, L101I, T122I, T124A, V151I, T206S  
17 IN_17 None    E11D, K14R, R20K, S24N, V31I, V32I, I60V, T112V, I113V, S119P, T122I, T124S, T125A, G134N, K136Q, V201I, L234I, S255N  
18 IN_18 None    E11D, K14R, S24N, V31I, M50I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, V201I, T218I, L234I, S255N  
21 IN_21 None    E11D, S24N, V31I, L45V, M50I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, V201I, L234I, S255N  
23 IN_23 None    E11D, K14R, S24N, V31I, M50I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, V201I, L234I, S255N  
27 IN_27 None    E11D, S24N, V31I, V32I, M50I, T112V, I113V, S119P, T124N, T125A, G134N, K136Q, V201I, T218I, L234I, S255N, D286N  
29 IN_29 None    K14R, S24N, V31I, M50I, L74I, T112V, S119P, T124S, T125A, G134N, K136Q, V201I, L234I, S255N  
IN_3 None    E11D, E13D, K14R, S24N, V32I, I72V, L74I, T112V, I113V, S119P, T124G, T125A, G134N, K136Q, V201I, N222K, L234I, S255N, I268V  
31 IN_31 None    D3E, S17C, R20K, V31I, D55N, L63V, I72V, L74I, T112A, S119P, T124S, T125A, G134N, K136Q, V201I, T218I, L234I, S255N  
32 IN_32 None    E11D, S24N, V31I, M50I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, V201I, L234I, S255N  
33 IN_33 None    E11D, K14R, S24N, L28M, V31I, V32I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, V201I, T218I, L234I, S255N  
36 IN_36 None    E11D, K14R, S24N, V31I, V32I, M50I, L101I, T112V, I113V, S119P, T124N, T125A, G134N, K136Q, V201I, T218I, L234I, S255N, V259I  
39 IN_39 None    E11D, K14R, S24N, V31I, M50T, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, V201I, T218I, L234I, S255N  
41 IN_41 None    E11D, K14R, S24N, V31I, M50I, T112V, I113V, S119P, T124N, T125A, G134N, K136Q, V201I, L234I, S255N  
42 IN_42 None    E11D, S24N, V31I, A49P, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, V201I, L234I, S255N  
43 IN_43 None    D3E, R20K, V31I, I72V, L74I, T112V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255N  
46 IN_46 None    E11D, K14R, S24N, V31I, M50I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, V165I, V201I, L234I, S255N  
50 IN_50 None    E11D, K14R, S24N, V31I, V32I, M50I, I72V, T112V, I113V, T124S, T125A, G134N, K136Q, V201I, T218I, L234I, S255N, E287A  
51 IN_51 None    D3E, R20K, V31I, I72A, L74I, T112V, I113V, S119P, T124S, T125A, G134D, K136Q, D167E, V201I, L234I, S255N C130F 
54 IN_54 None    E11D, K14R, S24N, V31I, M50I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, V201I, T218I, L234I, S255N  
55 IN_55 None    E11D, K14R, S24N, V31I, M50I, L74LI, T112V, I113V, S119P, T124N, T125A, G134N, K136Q, V201I, T218I, L234I, S255N  
56 IN_56.1 Unknown    E11D, K14R, S24N, V31I, M50L, T112V, I113V, S119P, T124N, T125A, G134N, K136Q, V165I, T218I, L234I, S255N  
57 IN_57 None    R20K, V31I, I60T, T112V, I113V, S119P, T124N, T125V, G134N, K136Q, D167E, V201I, T218I, L234I, S255N, I268V  
61 IN_61 None    E11D, K14R, S24N, V31I, V32I, L45Q, M50I, T112A, I113IV, S119P, T124S, T125A, G134N, K136Q, V201I, L234I, S255N, D279G  
IN_7 None    D3E, E11D, R20K, V31I, I72V, L74I, T112K, I113V, S119P, T124S, T125A, G134N, K136Q, G163E, D167E, G193E, V201I, Q216R, L234I, S255N  
97BL006 97BL006 None  P145PS G163R D3E, G4X, W19*, R20K, V31I, C40X, G47GR, A49X, G52GR, G59X, E69EK, G70GR, I72V, L74I, T112V, I113V, S119P, T124S, T125A, W132*, G134N, K136Q, D167E, H171Y, V201I, R224X, L234I, S255X, Y271X, G272GR, D278X E11EK, G140KR, W243W*, R269RGW 
98GEMZ001 98GEMZ001 None    D6E, E13D, I73V, L101I, T112I, T124A, T125V, S153T, Q216H  
98GEMZ004 98GEMZ004 None    S17N, V31I, F100Y, L101I, T112V, T124S, T125A, K136Q, V201I, T218I, L234I, A265V, D278A, S283G A76AP 
98GEMZ006 98GEMZ006 None    M22L, V37I, S39C, L45I, T112V, T124N, T125A, V126L, G163A, I220L, Y227F  
DEMA108RU003 DEMA108RU003 None    R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134D, K136Q, D167E, V201I, L234I, S255N  
DEMA108RU004 DEMA108RU004 None    E10K, R20K, V31I, D41N, I72V, L74I, E87K, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255N R107K 
DEURF08RU001 DEURF08RU001 None    E11D, K14R, S24N, D25E, V31I, L101I, T112V, T125A, G134N, I135V, K136T, V201I, T206S, L234I, R269K, S283G, D288N  
Irkutsk_5 Irkutsk_5 None    R20K, V32I, D41N, Q44H, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134D, K136Q, K156R, D167E, V201I, T218I, L234I, S255N  
KAL153 KAL153 None   E157Q S17G, L101V, T112I, T125A, K160Q, I161T, V201I, T218I, L234I, S255N  
KZKAR300435 02K300435 None    D3E, R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255N H51P 
KZPAV300480 02P300480 None    D3E, R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, K160R, D167E, V201I, T218I, L234I, S255N  
KZPAV300497 02P300497 None    D3E, S17N, R20K, V31I, V54I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255N  
KZPAV300502 02P300502 None    D3E, R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255N  
KZYUZ300413 02Y300413 None    D3E, R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, G163E, D167E, V201I, T218I, L234I, S255N  
KZYUZ300425 02Y300425 None    D3E, D6N, R20K, V31I, E35K, M50T, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255N  
RU00051 RU00051 Unknown    E11D, K14R, R20K, S24N, V31I, M50I, I72V, T112V, T124S, T125A, G134N, K136Q, D167E, V201I, K211R, L234V  
RU01029 RU01029 None    D3E, R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255N  
RU98001 RU98001 None   E157Q E11A, L101V, T112V, T122I, T125A, K160Q, V201I, T218I, L234I, S255N  
RUA001 RUA001 None    D3E, R20K, V31I, L63V, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255N, V281M  
RUA007 RUA007 None    R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255N, D270E  
RU_560_1125 RU_560_1125 None    D3E, R20K, D41N, I72V, L74I, T112V, S119P, T124S, T125A, G134D, K136Q, D167E, V201I, T218I, L234I, S255N  
RU_8141 RU_8141 Unknown    E11D, K14R, S24N, V31I, D41E, M50I, K111R, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, V201I, L234I, S255N C280CY 
RU_8169 RU_8169 Unknown    K14R, S24N, V31I, M50I, C56CY, S57SG, I72IV, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, V201I, I203M, T218I, L234I, S255N  
RU_8501 RU_8501 Unknown    E11D, K14R, S24N, V31I, M50I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, V201I, L234I, S255N  
RU_915_1016 RU_915_1016 None    D3E, E11D, R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255N W132G 
RU_915_1035 RU_915_1035 None    D3E, K7KQ, R20K, I72V, L74I, S81SR, T112V, I113V, S119P, T124S, T125A, G134N, K136H, D167E, V201I, T218I, L234I, S255N W132WG 
RU_915_1038 RU_915_1038 None    D3E, R20K, V31I, L74I, T112V, S119P, T124N, T125A, G134N, K136Q, E157EG, D167E, V201I, L234I, S255N  
RU_915_1041 RU_915_1041 None    V32I, I72V, L74I, K111R, T112V, I113V, T124S, T125A, G134N, K136Q, D167E, V201I, T218I, L234I, S255N, V259I  
RU_SP_B_049 RU_SP_B_049 None    D3E, R20K, V31I, I72V, L74I, T112V, I113V, S119P, T124S, T125A, G134N, K136Q, D167E, V201I, L234I, S255N