Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Alaoui (2019)
Title HIV-1 Integrase Resistance among Highly Antiretroviral Experienced Patients from Morocco.
Citation Intervirology
SelectedGene IN
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 78
NumPts 78
Subtype B, CRF02_AG, A, C

 

Clinical IN Isolates


SubjectIsolateINIsWksINIMajorINIMinorCommonUnusual
10121/14 10121/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
10135/14 10135/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N G197V 
10281/14 10281/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
10719/15 10719/15 None    E11D, I60M, K71Q, T122I, T124N, T125A, G193E, Q221H, S230N, S255G, D256E, D286N  
10722/15 10722/15 None    E11D, R20K, D25E, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
10773/14 10773/14 None    E11D, R20K, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
10867/15 10867/15 None   D232N E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, D286N  
11113/14 11113/14 None    E11D, L45I, M50I, L101I, K156N, E198D, V201I, D256E  
11291/14 11291/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
11528/15 11528/15 None    E11D, D25E, I60M, K71Q, S119R, T122I, T124N, T125A, G193E, Q221H, S230N, Q252L, N254S, S255G, D256E, D286N  
11562/11 11562/11 None    L45V, I72V, T124A, V201I, I203M, S230N  
11852/15 11852/15 None   D232N E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119R, T122I, T124N, T125A, G193E, Q221H, S255G, D256E, D286N  
1230/15 1230/15 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, D256E, D286N  
12427/14 12427/14 None   D232N E11D, R20K, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, D256E, D286N  
1245/14 1245/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
13297/14 13297/14 None    E11D, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, D256E, D286N  
14079/13 14079/13 None    V31I, K42Q, I72V, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, I203M, I208L, L234I, R269K, D278A, S283G  
1424/15 1424/15 None    E11D, K14R, V31I, V32I, T112I, S119P, T124N, V126M, V201I, K219N, N222K, S230N, D256E  
14349/11 14349/11 None    V31I, M50I, L101I, K111T, S119T, T124N, T125M, V201I, Y227F, S230N, R231K, D256E  
14642/13 14642/13 None    M50T, I60M, E96D, L101I, T112V, T124A, T125A, G134N, I135V, K136T, K156N, D167E, V201I, D229E, L234I, K240R, S283G  
14677/14 14677/14 None    L45Q, L101I, S119P, T125A, K211Q, D256E, D270N  
15433/14 15433/14 None    R20K, L101I, T112V, T124A, T125A, G134N, I135V, K136T, D167E, L234I, S283G  
1569/15 1569/15 None    E11D, K14R, S24N, V32I, L45I, L74M, A91T, L101I, T112I, T124A, T125A, G134N, I135V, K136T, V201I, T206S, T218I, L234I, N254K  
1607/15 1607/15 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119R, T122I, T124N, T125A, G193E, Q221H, D256E  
16139/14 16139/14 None    K14R, A21T, L45Q, L101I, S119P, T124N, T125A, V165I, I203M, D256E, I268L, D270N, D286N  
16344/13 16344/13 None    E11D, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
16753/14 16753/14 None    V31I, L74I, L101I, T112V, T124A, T125A, G134D, I135V, K136T, K188R, V201I, K215N, L234I, A265V, D288N  
20131/14 20131/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
20198/14 20198/14 None    E11D, R20K, V31I, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, V249I, D256E, R269K, S283G  
20214/14 20214/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N W243G 
20339/14 20339/14 None    E11D, S24G, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
20442/14 20442/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, D256E, D286N  
21339/14 21339/14 None    E11D, K14R, A21T, A23V, D25E, V31I, I72V, L74I, G106A, T112V, T125A, V126L, K136Q, D167E, V201I, L234I, S283G, D288N  
21378/14 21378/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
22056/14 22056/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
22110/14 22110/14 None    E11D, A21T, I72V, Q95P, L101I, K103R, S119P, T122I, T124A, D167E, K211Q, T218I  
2218/15 2218/15 None    E11D, I60M, S119P, T122I, T124N, T125A, G193E, Q221H, D256E, D286N  
2406/14 2406/14 None    E11D, R20K, S24G, D25E, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
2514/14 2514/14 None    E11D, K14R, A21T, V32I, S39C, L45Q, I72V, L101I, K103R, S119P, T122I, T125A, V165I  
2555/15 2555/15 None    E11D, S24G, L45Q, I60M, K71Q, S119R, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
2578/15 2578/15 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
2592/15 2592/15 None   D232N E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119R, T122I, T124N, T125A, G193E, D256E, D286N  
3375/15 3375/15 None    K14R, S17C, A21S, V31I, S39C, L101I, K103R, K111T, T112A, S119P, T122I, T124A, T125A, V201I, T206S, T218S, Y227F, D256E  
3413/14 3413/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
3613/14 3613/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
3674/15 3674/15 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, S255G, D256E, D286N  
3793/15 3793/15 None    L101I, T122I, T124N, T125A, V201I, T206S, T218I, L234I, N254K  
3846/14 3846/14 None    E11D, R20K, M50T, I60M, E96D, L101I, T112V, T124A, T125A, G134N, I135V, K136T, K156N, D167E, V201I, D229E, L234I, K240R, S283G  
4233/14 4233/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
4533/11 4533/11 None    E11D, K14R, A21T, V31I, V32I, S39C, L45Q, I72V, L101V, K103R, S119P, V165I  
4633/13 4633/13 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
4799/14 4799/14 None    E11D, D25E, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
4851/14 4851/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
5161/14 5161/14 None    S119P, T122I, T124N, T125A, Q221H, D256E  
5388/15 5388/15 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
5906/14 5906/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, S255G, D256E, D286N  
7173/14 7173/14 None    E13D, S17N, L28I, L101I, K111T, I113V, S119T, T124N, T125A, T218S, N222K, D256E, S283G  
7178/14 7178/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
7330/14 7330/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
7355/14 7355/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
7571/11 7571/11 None    V31I, M50I, L101I, S119T, L172I, T218S, Y227F, S230N, R231K, D256E  
7692/10 7692/10 None    K7R, E11D, V31I, T124A, T125A, I135V, V201I, T206S, K211Q, L234I  
7701/15 7701/15 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
7750/14 7750/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
8131/14 8131/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
8143/14 8143/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
8363/15 8363/15 None    E11D, S24G, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, S255G, D256E, D286N  
8380/14 8380/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
8464/14 8464/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, Q221H, D256E  
8489/13 8489/13 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
8576/14 8576/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
8577/14 8577/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
8658/15 8658/15 None    R20K, L101I, T112V, T124A, T125A, G134N, I135V, K136T, D167E, V201I, L234I, S283G  
9098/15 9098/15 None    E11D, R20K, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
9322/15 9322/15 None    E11D, R20K, L45Q, I60M, K71Q, S119R, T122I, T124N, T125A, G193E, Q221H, D256E, D286N  
9748/15 9748/15 None    E11D, K71Q, T124N, T125A, Q221H, S255G, D256E  
9762/14 9762/14 None    E11D, R20K, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N  
9876/14 9876/14 None    E11D, R20K, S24G, D25E, L45Q, I60M, K71Q, S119P, T122I, T124N, T125A, G193E, Q221H, S230N, N254S, S255G, D256E, D286N