Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Ara˙jo (2019)
Title Characterization of a large cluster of HIV-1 A1 infections detected in Portugal and connected to several Western European countries.
Citation Sci Rep
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 34
NumPts 34
Subtype A, B

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
z002 z002 None None   I37X, A98S, D123E, E169D, D177E, G196E, H208HY, R211K, F214L  
z003 z003 None None  V106I, G190A I37X, T200D, R211RK, F214L, V245K  
z004 z004 None None   I37X, E40D, K49R, V60I, K122E, D123N, I135T, K173V, Q174K, D177E, V179I, T200A, I202V, Q207A, L210S, R211S  
z008 z008 None None   I37X, E40ED, V60I, K122E, I135T, K173S, Q174K, D177E, I178IM, V179I, T200TA, Q207X, R211S, F214FL, V245K  
z010 z010 None None   I37X, K102Q, V118VI, D123E, I135T, I202V, R211K, F214L, V245K  
z011 z011 None None   I37X, R83K, S162C, T200TA, Q207E, R211K, V245K  
z013 z013 None None   I37X, T39K, R211K  
z036 z036 None None   I37X, E40D, K49R, V60I, K122E, D123N, K173A, Q174K, D177E, V179I, T200A, Q207A, R211S, F214FL, V245M  
z305 z305 None None   I37X, E40D, K49R, V60I, K122E, D123N, I135T, E169D, K173S, Q174K, V179I, T200A, Q207A, R211S, V245M  
z310 z310 None None   I37X, E40D, K49R, V60I, K122E, D123N, I135T, K173V, Q174K, D177E, V179I, Q207A, L210S, R211S  
z312 z312 None None   I37X, E40D, K49R, V60I, K122E, D123NS, T165I, K173AV, Q174K, D177E, V179I, Q207A, R211S K103KI 
z319 z319 None None   I37X, E40D, K49R, V60I, K122E, D123N, I135T, E169D, K173S, Q174K, N175Y, V179I, T200A, Q207A, R211S, V245M  
z321 z321 None None   I37X, E40D, K49R, V60I, K122E, D123N, I135T, E169D, K173S, Q174K, N175Y, V179I, T200A, Q207A, R211S, V245M  
z326 z326 None None   V35T, E40D, K49R, V60I, D123DN, I135T, E169D, K173AT, Q174K, I178IV, V179VI, Q207A, R211S, V245Q, D250E, K275Q, V276I, K281R, T286A, E291D, V292I, I293V, P294T, E312T, G335D  
z327 z327 None None   V35T, E40D, K49R, V60I, K122E, D123NS, I135T, S162A, K173L, Q174K, D177E, V179I, T200A, Q207A, R211S, E248D, D250E, A272G, T286A, E291D, V292I, I293V, P294T, G335D  
z328 z328 None None  A98AG V35T, E40D, I50IV, V60I, K122E, D123DN, F171FY, K173LS, Q174KR, D177E, V179I, T200A, Q207A, R211S, E248D, D250E, A272G, K277R, T286A, E291D, V292VIM, I293V, P294T, G335D  
z329 z329 None None   V35T, E40D, V60I, K122E, K173L, Q174X, D177E, V179X, Q182QH, T200A, Q207A, R211S, E248D, D250E, A272G, K277R, T286A, E291D, I293V, P294T, E312X, K323X, K331KN, Q334QH, G335D  
z330 z330 None None   V35T, E40D, K49R, I50IV, V60I, K122E, I135T, K173S, Q174K, D177E, V179I, T200A, Q207A, R211S, V245M, E248ED, D250E, A272G, T286A, E291D, V292VI, I293V, P294T, I326IT, I329ILV, G335D  
z331 z331 None None   V35T, E40D, K49R, I50V, V60I, K173S, Q174K, D177E, V179I, T200A, Q207A, R211S, D250E, A272GR, T286A, E291D, V292I, I293V, P294PT, Q334L, G335D  
z332 z332 None None  V106I, G190A V35VI, D86DE, V179I, T200D, R211K, F214L, V245K, V261VG, A272P, K277R, V292I, I293V, E297T, G333GE, Q334L  
z351 z351 None None  A98AG S48T, K122E, I135R, K173Q, D177E, Q207N, A272P, V276I, P294Q, L310I, I329V, G333E, Q334H  
z358 z358 None None   D123E, I135R, K173R, I178IL, I180IV, F214L, E291D, P294T, E297K, I329L  
z365 z365 None None   V35T, E40D, K49R, V60I, K122E, D123N, I135T, E169D, K173S, Q174K, V179I, T200A, I202V, Q207A, K275Q, K277R, K281R, T286A, E291D, I293V, P294T, G335D  
z366 z366 None None   V35T, E40D, K49R, V60I, K122E, D123N, I135T, E169D, K173S, Q174K, V179I, T200A, I202V, Q207A, R211RS, K275Q, K277R, K281R, T286A, E291D, I293V, P294T, G335D  
z367 z367 None None   V35T, E40D, K43KR, K49R, V60I, K101R, K122E, D123T, I135T, T165I, E169D, K173S, Q174K, V179I, T200A, Q207A, R211S, V245E, D250E, K275KQ, V276VI, K277KR, Q278QE, T286A, E291D, V292I, I293V, P294T, E312N, S322T  
z369 z369 None None   V35T, E40D, K49R, V60I, K122E, I135T, V148VG, K173S, Q174K, D177E, V179I, T200A, Q207A, R211S, I244V, V245M, E248ED, D250E, A272G, T286A, E291D, V292VI, I293V, P294T, G335D A158AG 
z370 z370 None None   K11KT, V35T, T39N, K122E, D123X, S162C, K173S, Q174K, D177E, T200TA, Q207A, R211K, E248D, A272S, T286A, E291D, V292I, I293V, K311R, I326V, E328D, G335D  
z371 z371 None None   V35T, E40D, K49R, V60I, K122E, D123S, I135T, E169D, K173LS, Q174K, V179I, T200A, I202V, Q207A, R211S, V245M, D250E, K277R, K281KR, T286A, E291D, V292I, I293V, P294T, E312N, G335D  
z372 z372 None None   K20R, V35T, E40D, K49R, V60I, K122E, D123N, I135T, E169D, K173A, Q174K, V179I, I202V, Q207A, R211S, V245Q, D250E, A272P, K275Q, V276I, K281R, T286A, E291D, I293V, P294T, E312N, G335D  
z376 z376 None None   K20R, V118I, D123E, K173R, R211K, F214L, A272G, E297K, I329L  
z381 z381 None None   V35I, K49R, V60I, S68G, R83RK, V90I, D123E, I178IM, V189I, T200A, R211K, A272P, T286A, E297K, I329L  
z383 z383 None None   V60I, I135T, I142IV, S162A, Q197E, R211RK, P243PA, V245E, E248D, D250E, V254I, A272P, K277R, T286A, I293V  
z384 z384 None None   K122KE, D123DN, I135T, S162C, G196E, Q207QH, R211X, F214L, E248D, A288S, I293V, K311KR, Q334L  
z385 z385 None None  V106I V35M, K122E, D123K, I135T, S162A, E169ED, E204Q, Q207E, R211K, F214L, V245K, T286A, S322T, I329L, G333E, Q334H