Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

References

Author Chen (2019)
Title Increased predominance of HIV-1 CRF01_AE and its recombinants in the Philippines.
Citation J Gen Virol
SelectedGene RT
SelectedSpecies HIV1
SelectedGroup M
SelectedType Clinical
NumIsolates 23
NumPts 23
Subtype CRF01_AE, B

 

Clinical RT Isolates


SubjectIsolateNRTIsNNRTIsNRTI MutNNRTI MutCommonUnusual
1001 1001 None None   K166R, K173E, V179I, I195P, G196A, Q197K, R211K, S251N, A272S, R284K, V292I, I293V, E312R, I326V, V365I, K385R, T403M, R461K, Q547R, A554T, K558R  
1002 1002 None None   E6D, D123E, I135T, S162A, T200I, V245K, I257L, A272P, K277R, I293V, E297A, R307K, V317A, G333E, G335S, R356K, G359S, T377Q, K390R, T450S, V466A, V467I, T470A, L491S  
1003 1003 None None   V60I, K102R, K104R, I135T, K173E, V179I, I195L, G196E, Q197K, I202V, S251N, A272S, V292I, I293V, E312K, I326V, V365I, T403M, V435E, R461K, K527N, Q547R, A554N, K558R  
1005 1005 None None   K122E, D123S, S162C, K173I, Q174K, D177E, T200A, Q207A, R211S, V245E, V276I, T286A, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, I375V, K390R, K395R, A400T, T403M, E404D, E432D, N447S, D471E, Q480H, L491S, K512R, L517I, S519N, Q524E, A534S, A554S  
1006 1006 None None   E6D, K11T, V35T, T39K, K43E, V60I, S68G, K122E, D123N, I135R, K173T, Q174K, D177E, I178M, V179I, T200V, Q207A, R211S, K238R, V245E, K275Q, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A376V, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, L517I, S519N, Q524E, A534S, A554S  
1007 1007 None None   E6D, K11T, V35T, T39K, K43E, V60I, S68G, K122E, D123N, I135R, K173I, Q174K, D177E, I178M, V179I, T200A, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A376V, A400T, T403M, E432D, N447S, D471E, Q480H, L491S, K512R, L517I, S519N, Q524E, A534S, A554S  
1008 1008 None None   P4S, E6D, V8I, K11T, V35T, T39K, K43E, V60I, K122E, D123S, I135T, K173I, Q174K, D177E, V179I, T200E, I202V, E204Q, Q207A, R211S, K238R, V245Q, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Y, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
1009 1009 None None   E6D, V35T, T39K, K43E, K122E, D123S, I135T, S162C, K173T, Q174K, D177E, I195L, T200A, Q207A, L210F, R211S, K238R, V245E, K281R, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, T377I, K390R, A400T, T403M, E404D, E432D, N447S, R448K, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
1010 1010 None None   E6D, V35T, T39K, K43E, V60I, K102R, K122E, D123S, K173T, Q174K, D177E, T200A, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312N, I326V, I329V, G335D, M357K, G359S, K366R, A371V, S379G, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Y, L491S, I505V, K512R, L517V, S519N, Q524E, A534S, A554S  
1011 1011 None None   E6D, V35T, T39K, K43E, T139A, I142T, S162C, K173I, Q174K, I178X, V179I, G196E, T200V, Q207A, R211S, A272S, V292I, I293V, E312T, I329V, G335D, M357K, G359S, K366R, A371V, A376S, K390R, A400T, T403M, E404D, E432D, N447S, D471E, Q480H, H483Y, L491S, L517V, S519N, Q524E, A534S, A554S, I556V  
1012 1012 None None   E6D, V21I, V35T, T39K, K43E, K49R, V60I, K122E, D123S, I135T, S163C, K173I, Q174K, D177E, I178M, E204Q, Q207A, R211S, K238R, I244V, V245E, K277R, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, T369A, A371V, K390R, K395R, A400T, T403M, E432D, N447S, R448K, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
1013 1013 None None   E6D, V8I, K11T, V35T, T39K, K43E, K49R, V60I, K122E, D123N, I135T, K173I, Q174K, D177E, I178V, V179I, T200A, I202V, E204Q, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E312T, I326V, I329V, G335D, Y342F, M357K, G359S, K366R, A371V, K390R, A400T, T403I, N447S, R461K, D471E, Q480H, H483Y, L491S, K512R, L517I, S519N, Q524E, A534S, A554S  
1021 1021 None None   E6D, V8I, K11T, V21I, V35T, T39K, K43E, V60I, K122E, D123S, I135T, S162C, K173L, Q174K, D177E, V179I, G196E, T200A, E204Q, Q207A, R211S, K238R, V245E, A272S, T286A, E291D, V292I, I293V, P294T, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, N447S, D471E, Q480H, H483Q, L491S, K512R, L517V, S519N, Q524E, K530R, A534S, A554S  
1022 1022 None None   V8I, K20R, V35I, T39A, R83K, A98S, K102R, D123E, S162C, F171Y, T200I, R211K, V245E, I293V, S322T, D324E, Q334L, K347R, M357T, K390R, A400T, D460N, R463K, L469I, T470P, H483Y, L484M, G490E, L491P, K512R, A554S, V559I  
1023 1023 None None   V60I, S68G, K103R, K122E, D123N, K166R, V245E, A272P, K277R, I293V, E297T, E312T, I326V, I329V, G335D, P345Q, F346H, M357K, G359S, K366R, A371V, K395R, A400T, E432D, D460N, D471E, Q480H, H483Y, L491S, K512R, E514D, L517I, S519N, Q524E, I526V, K530R, A534S, A554S  
1024 1024 None None   E6D, K11T, V21I, V35T, T39K, K43E, V60I, D121H, K122E, I142V, T165I, K173I, Q174K, D177E, I178M, T200A, Q207A, R211S, K238R, V245E, T286A, E291D, V292I, I293V, P294T, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, V435I, N447S, R448K, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S  
1025 1025 None None   E6D, V35T, T39K, K43E, K122E, D123S, R125K, S162C, K173I, Q174K, D177E, I195L, T200A, E203D, Q207A, R211S, K238R, V245A, T286A, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E404D, E432D, V458I, V466I, D471E, Q480H, H483Y, L491S, K512R, L517I, S519N, Q524E, V531I, A534S, A554S S379N 
1026 1026 None None   E6D, V35T, T39K, K43E, K122E, D123S, I135V, S162C, K173I, Q174K, D177E, I195L, T200A, Q207A, L210M, R211S, K238R, V245E, T286A, E291D, V292I, I293V, E297G, E312T, I326V, I329V, G335D, M357K, G359S, D364N, K366R, A371V, T386I, K390R, E399D, A400T, T403M, E404D, E432D, N447S, Q464R, D471E, Q480H, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
1027 1027 None None   E6D, V8I, V21I, V35T, T39K, K43E, V60I, K122E, D123S, K173I, Q174K, D177E, I178V, V179I, T200A, Q207A, R211S, K238R, V245E, E291D, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, N447S, R448K, D471E, Q480H, L491S, K512R, L517I, S519N, Q524E, A534S, A554S  
1028 1028 None None   E6D, V8I, V21I, V35T, T39K, K43E, V60I, K122E, D123S, K173I, Q174K, D177E, V179I, T200A, E204Q, Q207A, R211S, K238R, V245E, E291D, V292I, I293V, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403M, E432D, N447S, R448K, Q464K, D471E, Q480H, G490E, L491S, K512R, L517I, S519N, Q524E, K530R, A534S, A554S  
1029 1029 None None   E6D, V8I, V21I, V35T, T39K, K43E, V60I, S68G, K122E, D123N, I135R, S162C, K173V, Q174K, D177E, I178M, T200A, Q207A, R211S, K238R, V245E, K277R, T286A, E291D, V292I, I293V, E297A, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, A400T, T403M, E432D, N447S, D471E, Q480H, H483Y, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
1030 1030 None None   E6D, V35T, T39K, K43E, V60I, K122E, D123S, I135K, S162C, K173T, Q174K, D177E, I178M, T200A, Q207A, L210M, R211S, K238R, V245E, L283I, V292I, I293V, E312T, I326V, I329V, G335D, R356K, M357R, G359S, A371V, K390R, A400T, T403R, E432D, V435A, N447S, D471E, Q480H, H483Y, L484I, L491S, K512R, L517V, S519N, Q524E, A534S, A554S  
1031 1031 None None   P4H, E6D, K11T, V35T, T39K, K43E, V60I, K64R, K102N, V111I, G112E, K122E, D123S, I135T, K173I, Q174K, D177E, I178M, V179I, E194K, T200A, E204K, Q207A, R211S, K238R, V245K, K281R, T286A, E291D, V292I, I293V, P294T, E300K, E312T, I326V, I329V, G335D, M357K, G359S, K366R, A371V, K390R, A400T, T403V, E432D, N447S, D471E, Q480H, L491S, K512R, L517I, S519N, Q524E, A534S, A554S, K558R